Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Olle Söder"'
Autor:
Sheyla Cisneros Montalvo, Jan-Bernd Stukenborg, Zeliha Sahin, Halima Albalushi, Olle Söder, Mirja Nurmio, Jorma Toppari, Mi Hou, Niels Geijsen, Ahmed Reda
Publikováno v:
Annals of Biomedical Engineering, 45(7), 1783-1794. Springer Netherlands
Annals of Biomedical Engineering
Annals of Biomedical Engineering
Finding robust culture conditions for in vitro maturation (IVM) of male germ cells is still a challenge. Recently, a testis organ culture method, using Knockout Serum Replacement (KSR), was suggested as a promising approach. However, the efficiency o
Autor:
Antonella Puglianiello, Daniela Germani, Ahmed Reda, Valentina Pampanini, Jan-Bernd Stukenborg, Stefano Cianfarani, Iuliia Savchuk, Kristín Rós Kjartansdóttir, Olle Söder
Publikováno v:
The Journal of Endocrinology
Prenatal events such as intrauterine growth restriction can affect gonadal development of the offspring and have an impact on reproductive health. To investigate the effects of intrauterine growth restriction induced by uterine artery ligation on the
Autor:
Olle Söder, Ulrike Lossner, Gloria-Maria Manjowk, Susan Kralisch, Matthias Blüher, Mathias Fasshauer, Isabel Viola Wagner, Michael Stumvoll, Beate Jessnitzer, Thomas Ebert, Jan-Bernd Stukenborg, Annett Hoffmann, Konstantin Svechnikov, Nora Klöting
Publikováno v:
Endocrinology. 157:2461-2468
Obesity has recently been linked with reduced fertility, and the mechanisms underpinning this effect are currently unknown. The adipokine leptin is dysregulated in obesity and affects reproductive tracts; therefore, we investigated the dose-dependent
Autor:
Siladitya Bhattacharya, Bruno Le Bizec, Olle Söder, Iuliia Savchuk, Ugo Soffientini, Denise Hough, Zoe C. Johnston, Panagiotis Filis, Michelle Bellingham, Paul Fowler, Peter J. O'Shaughnessy, Marie-Line Morvan, Jean-Philippe Antignac, Natasha Walker, Ana Monteiro, Konstantin Svechnikov
Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef37cfecde8a48a3c1b980c7f468a841
https://doi.org/10.1101/365122
https://doi.org/10.1101/365122
Autor:
Artur Mayerhofer, Luise Landreh, Merja R. Häkkinen, Kerstin Schubert, Konstantin Svechnikov, Olle Söder, Matti Poutanen, Katrin Spinnler, Seppo Auriola
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E1227-E1235
Aim: We aim to examine the steroidogenic phenotype and the differentiation potential of human testicular peritubular cells (HTPCs) and to explore their possible relationship to the adult Leydig cell lineage. Background: The cells of the adult Leydig
Publikováno v:
Molecular and Cellular Endocrinology. 372:96-104
Platelet-derived growth factor receptor α (PDGFRα)-positive peritubular cells (PTCs) are suggested to be putative stem Leydig cells. At present little is known about their phenotype and steroidogenic potential. We isolated highly purified PDGFRα-p
Autor:
Olle Söder, Mirja Nurmio, E. M. Ritzén, Agneta Nordenskjöld, Jorma Toppari, E. Sundqvist, T. Gustafsson, Jan-Bernd Stukenborg, Claude Kollin
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 97:4588-4595
A randomized controlled study was conducted comparing the outcome of surgery for congenital cryptorchidism at 9 months or 3 yr of age.The aim of the study was to investigate whether surgery at 9 months is more beneficial than at 3 yr and to identify
Publikováno v:
Journal of Steroids & Hormonal Science. 7
The secretory insulin-like growth factor-binding protein-3 (IGFBP-3) induces apoptosis via both insulin-like growth factor-I (IGF-I)-dependent and -independent mechanisms. Here, we have examined the effects of IGFBP-3 on Leydig cell apoptosis, prolif
Publikováno v:
International Journal of Andrology. 32:66-73
Elimination of contaminating malignant cells is crucial to avoiding cancer relapse in association with transplantation of autologous spermatogonial stem cells. In the clinical setting, there is presently no effective procedure for separating testicul
Autor:
Christine Carlsson-Skwirut, Olle Söder, Olle Larsson, Magnus Axelson, Konstantin Svechnikov, Farasat Zaman, Eugenia Colón
Publikováno v:
Endocrinology. 148:128-139
The present investigation examines the influence of IGF-I and the role of IGF-I receptor (IGF-IR) in the apoptosis/survival of Leydig cells. Immunohistochemical analysis of the rat testis at different ages revealed that the level of the phosphorylate