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Publikováno v:
American Journal of Physiology-Renal Physiology. 318:F639-F646
Little is known about changes in parathyroid cells when calcimimetics are withdrawn. We examined the response of parathyroid glands to cinacalcet (Cina) withdrawal in uremic Sprague-Dawley rats fed a high-phosphate diet to develop secondary hyperpara
Autor:
Dudley W. Lamming, Michelle Sonsalla, Nadine P. Connor, Natalie Morel, Oleg Broytman, Christopher Setzke, Mihaela Teodorescu, John A. Russell
Publikováno v:
J Appl Physiol (1985)
Obstructive sleep apnea (OSA) is more common in patients with asthma, and inhaled corticosteroids may contribute to OSA pathogenesis in these patients. This study tested the effects of orally inhaled fluticasone propionate (FP) on extrinsic tongue mu
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Psychomotor stimulants are prescribed for many medical conditions, including obesity, sleep disorders, and attention-deficit/hyperactivity disorder. However, despite their acknowledged therapeutic utility, these stimulants are frequently abused, and
Autor:
Sisareuth Tan, Jean-Sébastien Silvestre, Kamaleswaran Keirththana, Alain Brisson, Thi Anh-Dao Tran, José Vilar, Philippe Menasché, Paul Alayrac, Thomas Hamada, Maria Franca Perotto, Nadia El Harane, Reem Al-Daccak, Dominique Charron, Laetitia Pidial, Valérie Bellamy, Nisa Renault, Hocine Rachid Hocine, Chloé Guillas, Manon Desgres, Ingrid Gomez, Bruna Lima Correa
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
AimsThe cardioprotective effects of human induced pluripotent stem cell-derived cardiovascular progenitor cells (CPC) are largely mediated by the paracrine release of extracellular vesicles (EV). We aimed to assess the immunological behaviour of EV-C
Autor:
Olena Dolzhykova, Ludmila Maloshtan
Publikováno v:
ScienceRise: Pharmaceutical Science, Vol 0, Iss 1 (23), Pp 29-33 (2020)
The aim.To study the therapeutic effect of new vaginal suppositories "Melanizol" based on metronidazole and tea tree oil on a model of "mechanical" vaginitis in female rats. Methods.The therapeutic effect of suppositories of "Melanizol" has been stud
Autor:
Juan Zheng, Ning Wang, Shan Lei, Xinlin Chen, Pengbo Zhang, Weisong Li, Yang Lu, Rong Li, Yuanyuan Zhang, Zhengguo Qiu, Jieqiong Wen, Haidong Wei, Pan Lu, Hong Zhang, Yong Liu, Jing Xu, Haixia Lv, Kui Wang
Publikováno v:
ACS Chemical Neuroscience. 11:579-591
Midazolam, a widely used anesthetic, inhibits proliferation of neural stem cells (NSCs) and induces neuroapoptosis in neonates. Dexmedetomidine, an effective auxiliary medicine in clinical anesthesia, protects the developing brain against volatile an
Autor:
Francisco de Assis Leite Souza, Álvaro Aguiar Coelho Teixeira, Welma Emídio da Silva, Yuri Mateus Lima de Albuquerque, Valéria Wanderley Teixeira
Publikováno v:
JBRA Assisted Reproduction
We evaluated the evidence in research on the effects of melatonin on hypothyroidism and gonadal development. According to the World Health Organization, thyroid disorders due to iodine deficiency affect about 740 million people worldwide. Hypothyroid
Autor:
Peter M.B. Cahusac, Solomon S. Senok
Publikováno v:
Skin Pharmacology and Physiology. 33:253-260
Background: The pharmacological study of mechanoreceptors embedded within tissue is hampered by tissue barriers to applied research drugs. Methods: Hyaluronidase increases the permeability of tissues and is used clinically to facilitate the distribut
Autor:
Heba Morsi, Hanan Abdallah, Ghada Farouk Soliman, Nermeen Bastawy, Walaa Ibrahim, Omnia Mohamed Abdel-Maksoud, Mohamed Mansour Khalifa, Laila A. Rashed
Publikováno v:
Archives of Physiology and Biochemistry. 128:463-473
Aim: High cholesterol diet is greatly linked to deleterious health consequences. In this work we tried to explore direct effects of high cholesterol diet on striated (skeletal and cardiac) muscle tissues and the mechanisms by which nebivolol could im
Autor:
Armando Pérez-Torres, Rosalía Hernández-Cervantes, Jorge Morales Montor, Oscar Prospéro-García
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
The consequences of marijuana consumption during pregnancy and its effects on the function of the immune system have been little studied. Marijuana is one of the most consumed recreational drugs among pregnant women, and it is known that gestational