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of 21
pro vyhledávání: '"J Aitken"'
Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes
Autor:
Clare Megson, Anna E. Long, Isabel V. Wilson, F. Susan Wong, Rachel J Aitken, Stephanie J. Hanna, Kathleen M Gillespie, Joanne Boldison
Publikováno v:
Diabetologia
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0
Aims/hypothesis Slow progressors to type 1 diabetes are individuals positive for multiple pancreatic islet autoantibodies who have remained diabetes-free for at least 10 years; regulation of the autoimmune response is understudied in this group. Here
Autor:
Stephanie J. Hanna, Claire Megson, Kathleen M Gillespie, Isabel V. Wilson, Anna E. Long, F. Susan Wong, Joanne Boldison, Rachel J Aitken
ObjectiveTo profile CD4+ regulatory T cells (Tregs) in a well-characterised cohort of slow progressors to type 1 diabetes, individuals positive for multiple islet autoantibodies who remain diabetes-free for at least 10 years.Research Design and Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2899780e02b66f97150344332cddb3e
https://doi.org/10.1101/2021.01.13.21249751
https://doi.org/10.1101/2021.01.13.21249751
Publikováno v:
Annals of Oncology. 21:1254-1261
Background Assessment of receptors [estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2)] is routinely carried out on primary tumour in order to select appropriate adjuvant therapy; the same analysis
Autor:
Uta Frith, Kenneth J. Aitken
Publikováno v:
Developmental Medicine & Child Neurology. 33:930-934
Autor:
K K Singh, R J Aitken
Publikováno v:
British Journal of Surgery. 86:1332-1336
Background The surgeon is an important variable that influences outcome following colorectal cancer surgery. Operative training of suitable quality and quantity is essential if intersurgeon variation is to be reduced. The aim of this study was to exa
Autor:
A. R. van der Slik, Geoffrey V. Gill, Stephen C. Bain, Kathleen M Gillespie, Rachel J Aitken, Bart O. Roep, Anna E. Long, KL Mehers, V Nathwani, Polly J. Bingley, Florence Susan Wong
Publikováno v:
Diabetologia, 54(12), 3062-3070
Natural killer (NK) cells serve as primary immune surveillance and are partially regulated by combinations of killer immunoglobulin-like receptor (KIR) genes and their HLA class I ligands. Alterations in NK cell activity have been associated with typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c309cb8082cdb84b634c4c0e557f56a8
http://hdl.handle.net/1887/110948
http://hdl.handle.net/1887/110948
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 77:1622-1628
C19 steroids are converted to estrogens in a number of tissues by a specific form of cytochrome P450, namely aromatase cytochrome P450 (P450arom). Adipose tissue is the principal site of estrogen formation in postmenopausal women. Aromatase activity
Autor:
Jenny Mountain, Syed Aqif Mukhtar, Natasha S. Haynes, Robert J. Aitken, James B. Semmens, Frank M Sanfilippo
Publikováno v:
The Medical journal of Australia. 183(10)
Objective: To describe the peer review process of the Western Australian Audit of Surgical Mortality (WAASM), selected outcomes and recommendations. Study design: Prospective audit using peer review of all cases of patients who died while under the c
Autor:
R. J. Aitken
Publikováno v:
British Journal of Surgery. 83:214-216
A series of 103 consecutive rectal cancers was prospectively documented. Laparotomy was performed in 78 patients of whom five did not undergo resection. Resection was considered curative unless there were liver metastases or biopsy-proven residual di
Summary A 58 year old man underwent a laparotomy for intestinal obstruction, which proved to be due to intestinal pseudo-obstruction. Following a slow postoperative course, he was discovered to have a gastric phytobezoar. The association between bezo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969a1e6bfbd30236f9af89b4442a5ca9
https://europepmc.org/articles/PMC2399698/
https://europepmc.org/articles/PMC2399698/