Zobrazeno 241 - 250
of 9 956
pro vyhledávání: '"11"'
Autor:
Lu Tian, Wanfang Li, Jinfeng Wei, Zhi Zhou, Yanhua Chen, Zhonghua Wang, Wenqing Fu, Yaqi Liu, Baili Wang, Bingshu He, Meiling Huo, Jianzhen Xia, Zeper Abliz
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3665-3677 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy (DN) is vital for more accurate understanding the molecular pathological signature and developing novel therapeutic strategies. In the present study, a spatial-reso
Autor:
Ruiqian Sun, Jianfeng Pei, Qian Li, Wen Zhang, Xinyu Cao, Weili Wu, Yongjun Zhang, Ping Yuan, Rong Hu, Jiajian Zhou
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 11, Iss 11, Pp 3032-3050 (2021)
FEBS Open Bio, Vol 11, Iss 11, Pp 3032-3050 (2021)
There were approximately 1.93 million new cases and 940 000 deaths from colorectal cancer in 2020. The first‐line chemotherapeutic drugs for colorectal cancer are mainly based on 5‐fluorouracil, although the use of these drugs is limited by the d
Autor:
Gordon D. Waiter, Claire Green, Mathew A. Harris, J. Douglas Steele, Anca-Larisa Sandu, Joanna M. Wardlaw, David J. Porteous, Heather C. Whalley, Liana Romaniuk, Emma L. Hawkins, Rebecca M. Reynolds, Xueyi Shen, Miruna C. Barbu, Aleks Stolicyn, Jonathan R. Seckl, Andrew M. McIntosh, Stephen M. Lawrie, Jonathan Cavanagh, Archie Campbell
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Green, C, Stolicyn, A, Harris, M A, Shen, X, Romaniuk, L, Barbu, M C, Hawkins, E L, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A, Campbell, A, Porteous, D J, Seckl, J R, Lawrie, S M, Reynolds, R M, Cavanagh, J, Mcintosh, A M & Whalley, H C 2021, ' Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland ', Translational Psychiatry, vol. 11, no. 1 . https://doi.org/10.1038/s41398-021-01644-9
Translational Psychiatry
Green, C, Stolicyn, A, Harris, M A, Shen, X, Romaniuk, L, Barbu, M C, Hawkins, E L, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A, Campbell, A, Porteous, D J, Seckl, J R, Lawrie, S M, Reynolds, R M, Cavanagh, J, Mcintosh, A M & Whalley, H C 2021, ' Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland ', Translational Psychiatry, vol. 11, no. 1 . https://doi.org/10.1038/s41398-021-01644-9
Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been commonly reported in major depressive disorder (MDD), but with considerable heterogeneity of results; potentially due to the predominant use of acute measures of an inherently varia
Autor:
Sussi Bagge Mortensen, Kate Lykke Lambertsen, Ann-Brit Eg Hansen, Isik Somuncu Johansen, Marianne Antonius Jakobsen, Hans Christian Beck, Trine H. Mogensen, Eva Bang Harvald, Ditte Caroline Andersen
Publikováno v:
Mortensen, S B, Hansen, A B E, Mogensen, T H, Jakobsen, M A, Beck, H C, Harvald, E B, Lambertsen, K L, Johansen, I S & Andersen, D C 2021, ' Pyrin Inflammasome Activation Abrogates Interleukin-1 Receptor Antagonist, Suggesting a New Mechanism Underlying Familial Mediterranean Fever Pathogenesis ', Arthritis and Rheumatology, vol. 73, no. 11, pp. 2116-2126 . https://doi.org/10.1002/art.41770
Mortensen, S B, Hansen, A-B E, Mogensen, T H, Jakobsen, M A, Beck, H C, Harvald, E B, Lambertsen, K L, Johansen, I S & Andersen, D C 2021, ' Pyrin Inflammasome Activation Abrogates Interleukin-1 Receptor Antagonist, Suggesting a New Mechanism Underlying Familial Mediterranean Fever Pathogenesis ', Arthritis & Rheumatology, vol. 73, no. 11, pp. 2116-2126 . https://doi.org/10.1002/art.41770
Mortensen, S B, Hansen, A-B E, Mogensen, T H, Jakobsen, M A, Beck, H C, Harvald, E B, Lambertsen, K L, Johansen, I S & Andersen, D C 2021, ' Pyrin Inflammasome Activation Abrogates Interleukin-1 Receptor Antagonist, Suggesting a New Mechanism Underlying Familial Mediterranean Fever Pathogenesis ', Arthritis & Rheumatology, vol. 73, no. 11, pp. 2116-2126 . https://doi.org/10.1002/art.41770
Objective: Aberrant pyrin inflammasome activity triggers familial Mediterranean fever (FMF) pathogenesis, but the exact mechanism remains elusive and an obstacle to efficient treatment. We undertook this study to identify pyrin inflammasome–specifi
Publikováno v:
Міжнародний ендокринологічний журнал-Mìžnarodnij endokrinologìčnij žurnal; Том 16, № 3 (2020); 227-230
Международный эндокринологический журнал-Mìžnarodnij endokrinologìčnij žurnal; Том 16, № 3 (2020); 227-230
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY; Том 16, № 3 (2020); 227-230
Международный эндокринологический журнал-Mìžnarodnij endokrinologìčnij žurnal; Том 16, № 3 (2020); 227-230
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY; Том 16, № 3 (2020); 227-230
Background. The purpose is to present clinical observations of diseases of workers in individual industries, where a priori there was an effect of various production chemical factors that caused damage to the cardiovascular system such as coronary he
Publikováno v:
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine). 15:23-26
Background. 5’AMP-activated protein kinase (AMPK) is an enzyme that controls the cell energy balance. With energetic stress in the cell and an increase in the AMP concentration, ATP is replaced by AMP in the exchange centers, resulting in the all
Autor:
Josiane do Carmo Silva, Tiago Tomazi, M. Pallu, M. Cruzado-Bravo, T.R. Bilby, Rodrigo C. Bicalho, L. Bringhenti, Marjory Xavier Rodrigues, A.C.C.H. Tomazi
Publikováno v:
Journal of Dairy Science. 104:10291-10309
The objective of this randomized clinical study was to compare the effect of 2 antimicrobial interventions, tildipirosin or florfenicol + flunixin meglumine, used for treatment of pneumonia and extralabel treatment for otitis on health parameters and
Autor:
Tatsuyoshi Yamamoto, Takashi Hamazaki, Yuji Sato, Sairei So, Kazunori Tanizawa, Hiroyuki Sonoda, Toshiyuki Seto, Kazuyoshi Tomita, Shungo Okamoto
Publikováno v:
JIMD Reports
JIMD Reports, Vol 62, Iss 1, Pp 9-14 (2021)
JIMD Reports, Vol 62, Iss 1, Pp 9-14 (2021)
Mucopolysaccharidosis type II (MPS II; Hunter syndrome) is an X‐linked recessive lysosomal storage disease caused by a mutation in the IDS gene and characterized by systemic accumulations of glycosaminoglycans. Its somatic symptoms can be relieved
Autor:
Dina K Gaynullina, Lyubov D Shilova, Olga S. Tarasova, Ekaterina K Selivanova, Anastasia A. Shvetsova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Intrauterine growth restriction (IUGR) is one of the most common pathologies of pregnancy. The cardiovascular consequences of IUGR do not disappear in adulthood and can manifest themselves in pathological alterations of vasomotor control. The hypothe
Autor:
Florent Malard, Jean-Luc Harousseau, Ali Bazarbachi, Abdul Hamid Bazarbachi, Mohamad Mohty, Rama Al Hamed
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 5, Pp 1-13 (2021)
Blood Cancer Journal
Blood Cancer Journal, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Blood Cancer Journal, Nature Publishing Group, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Blood Cancer Journal
Blood Cancer Journal, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Blood Cancer Journal, Nature Publishing Group, 2021, 11 (5), pp.97. ⟨10.1038/s41408-021-00486-4⟩
Amyloid light chain (AL) amyloidosis is among the more common and more severe of the amyloidoses usually involving the slow proliferation of a bone-marrow-residing plasma cell (PC) clone and the secretion of unstable immunoglobulin-free light chains