Zobrazeno 1 - 3
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pro vyhledávání: '"Yongle Pang"'
Autor:
Wilson Edwards, Yue-Mei Zhang, Shengsheng Xu, Raul C. Camacho, Wenying Jian, Lijuan Kang, Yongle Pang, Naidong Weng, Tom Kirchner, Norquay Lisa
Publikováno v:
Bioanalysis. 13:465-479
Aim: To further enhance the detection sensitivity and increase resolving power of top-down intact protein bioanalysis, middle-down approach was explored. Materials & methods: An monoclonal antibody (mAb) was used as a model protein to evaluate quanti
Publikováno v:
Analytical Chemistry. 87:10942-10949
Monoclonal antibodies (mAbs) are the fastest growing class of therapeutic drugs, because of their high specificities to target cells. Facile analysis of therapeutic mAbs and their post-translational modifications (PTMs) is essential for quality contr
Autor:
Yongle Pang, Hui Yin Tan, Nitin Patel, Weijing Liu, Adrian Guthals, Gia Jokhadze, Merlin L. Bruening
Publikováno v:
The Analyst. 143(16)
Proteolytic digestion is an important step in characterizing protein sequences and post-translational modifications (PTMs) using mass spectrometry (MS). This study uses pepsin- or trypsin-containing spin membranes for rapid digestion of single protei