Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Xinxin Ding"'
Autor:
Xiaoguo Zhang, Xinxin Ding, Richard Scott Marshall, Julio Paez-Valencia, Patrick Lacey, Richard David Vierstra, Marisa S Otegui
Publikováno v:
eLife, Vol 9 (2020)
Reticulon (Rtn) proteins shape tubular domains of the endoplasmic reticulum (ER), and in some cases are autophagy receptors for selective ER turnover. We have found that maize Rtn1 and Rtn2 control ER homeostasis and autophagic flux in endosperm aleu
Externí odkaz:
https://doaj.org/article/116395153ecd4b16b4f38f7ca3d6fe8b
Autor:
Zhenwang Jie, Yu Zhang, Chen Wang, Bin Shen, Xin Guan, Zhihua Ren, Xinxin Ding, Wei Dai, Yongping Jiang
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180832 (2017)
Conventional high-dose chemotherapy frequently leads to severe neutropenia, during which patients experience a high risk of infection. Although support care with donor's neutrophils is possible this choice is largely hampered by the limited availabil
Externí odkaz:
https://doaj.org/article/741394e3048040e483ca558d57faa2cd
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141485 (2015)
Stem cell factor (SCF) can stimulate hematopoietic stem cell (HSC) expansion; however, the specific structural region(s) of SCF protein that are critical for this function are still unknown. A novel monoclonal antibody (named 23C8) against recombinan
Externí odkaz:
https://doaj.org/article/e2b2115150124fea9e38954473c2aa05
Autor:
Yan Zhang, Fang Dong, Na Zhang, Hui Cheng, Yakun Pang, Xiaomin Wang, Jing Xu, Xinxin Ding, Tao Cheng, Jun Gu, Weiping Yuan
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69913 (2013)
BACKGROUND: Bone marrow microenvironment (niche) plays essential roles in the fate of hematopoietic stem cells (HSCs). Intracellular and extracellular redox metabolic microenvironment is one of the critical factors for the maintenance of the niche. C
Externí odkaz:
https://doaj.org/article/3027a5e22d07472cb3ba37cbe5e4db98
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35206 (2012)
Cyclic diguanosine monophosphate (c-di-GMP) and cyclic diadenosine monophosphate (c-di-AMP) are recently identified signaling molecules. c-di-GMP has been shown to play important roles in bacterial pathogenesis, whereas information about c-di-AMP rem
Externí odkaz:
https://doaj.org/article/f5c164b992ab41ee9360f8b9c4ad24cf
Autor:
Hong-Chang Lai, Xinxin Ding, Xiangbing Wu, Wen Gu, Xiao Zhang, Yi Zhang, Yuan Li, Jianxu Wei, Shi-Chong Qiao, Xiaomeng Zhang, Jun-Yu Shi, Ying-Xin Gu, Wei Wang
Publikováno v:
Acta Biomaterialia. 134:325-336
Peri‑implantitis, which is characterized by peri‑implant mucositis and alveolar bone resorption, significantly shortens the service life of dental implants. Melatonin is well-known for its anti-inflammatory and osteoprotective activities. Neverth
Publikováno v:
Toxicol Sci
Previous studies have established that cytochrome P450 enzymes (CYPs) in both liver and lung are capable of bioactivating naphthalene (NA), an omnipresent air pollutant and possible human carcinogen, in vitro and in vivo. The aim of this study was to
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 123-135 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 123-135 (2020)
We examined the impact of gut inflammation on the expression of cytochrome P450 (P450) and other biotransformation genes in male mice using a dextran sulfate sodium (DSS)-induced colitis model. Several P450 isoforms, including CYP1A, CYP2B, CYP2C, an
Autor:
Senyan Liu, Stewart Sell, Lei Li, Kathleen G. Dickman, Changlin Mei, Xinxin Ding, Xiaochen Bao, Liang Ding, Jun Gu, Qing Yu Zhang
Publikováno v:
Toxicol Sci
The effect of variations in the expression of cytochrome P450 reductase (CPR or POR) is determined in mice with decreased POR expression to identify potential vulnerabilities in people with low POR expression. There is an age-dependent appearance of
Publikováno v:
Drug Metabolism and Disposition. 47:1469-1478
Previous studies using Cyp2abfgs-null (lacking all genes of the Cyp2a, 2b, 2f, 2g, and 2s subfamilies), CYP2A13/2F1-humanized, and liver-Cpr-null (LCN) mice showed that although hepatic cytochrome P450 (P450) enzymes are essential for systemic cleara