Zobrazeno 61 - 70
of 245
pro vyhledávání: '"Tanja D de Gruijl"'
Autor:
André Lieber, Joao Manuel Santos, Hongjie Wang, Riikka Havunen, Suvi Sorsa, Anna Kanerva, Victor Cervera-Carrascon, Sadia Zafar, Akseli Hemminki, Mikko Siurala, Otto Hemminki, Tanja D. de Gruijl
Publikováno v:
Cancer Immunology Research. 8:B07-B07
Dendritic cell (DC) therapy is considered a promising immunotherapeutic approach for treatment of advanced cancer. However, the immunosuppressive tumor microenvironment leads to DC dysfunction. Therefore, in clinical trials DC therapy has generally f
Autor:
Dafne Carolina Alves Quixabeira, Anna Kanerva, Mikko Siurala, Tanja D. de Gruijl, Joao Manuel Santos, Akseli Hemminki, Heini Lassus, Victor Cervera-Carrascon, Camilla Heiniö
Publikováno v:
Cancer Immunology Research. 8:A15-A15
The natural occurrence of immune cells in the tumor microenvironment of ovarian cancer (OC) facilitates the ex vivo generation and expansion of tumor-infiltrating lymphocytes (TIL) for infusion in the context of adoptive T-cell transfer. Yet, the lac
Autor:
Sanne Nieuwenhuizen, Martijn R. Meijerink, Tanja D. de Gruijl, Alette H. Ruarus, Hester J. Scheffer, Robbert S. Puijk, Bart Geboers
Publikováno v:
Geboers, B, Ruarus, A H, Nieuwenhuizen, S, Puijk, R S, Scheffer, H J, de Gruijl, T D & Meijerink, M R 2019, ' Needle-guided ablation of locally advanced pancreatic cancer : cytoreduction or immunomodulation by in vivo vaccination? ', Chinese clinical oncology, vol. 8, no. 6, 61 . https://doi.org/10.21037/cco.2019.10.05
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive forms of cancer with a dismal prognosis. About a third of all patients with pancreatic cancer present with locally advanced inoperable disease and are currently designated to palli
Autor:
Tanja D. de Gruijl, Jeroen Rovers, Arjan A. van de Loosdrecht, Luca L.G. Janssen, Jacqueline Cloos, Theresia M. Westers, Peter J. M. Valk
Publikováno v:
Blood. 134:1381-1381
Background. Maintenance of induced responses remains a significant unmet medical need in patients with acute myeloid leukemia (AML) or high risk myelodysplastic syndrome (MDS) not eligible for allogeneic hematopoietic stem cell transplantation (HSCT)
Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs
Autor:
Qiana L. Matthews, Tanja D. de Gruijl, Anita G.M. Stam, Rieneke van de Ven, Igor P. Dmitriev, Tracy Jane T.H.D. Eisden, Erik Hooijberg, David T. Curiel, Mert Icyuz, Dafni Chondronasiou
Publikováno v:
Vaccines
Volume 6
Issue 3
Vaccines, 6(3). Multidisciplinary Digital Publishing Institute (MDPI)
Vaccines, Vol 6, Iss 3, p 42 (2018)
Chondronasiou, D, Eisden, T-J T H D, Stam, A G M, Matthews, Q L, Icyuz, M, Hooijberg, E, Dmitriev, I, Curiel, D T, de Gruijl, T D & van de Ven, R 2018, ' Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs ', Vaccines, vol. 6, no. 3 . https://doi.org/10.3390/vaccines6030042
Volume 6
Issue 3
Vaccines, 6(3). Multidisciplinary Digital Publishing Institute (MDPI)
Vaccines, Vol 6, Iss 3, p 42 (2018)
Chondronasiou, D, Eisden, T-J T H D, Stam, A G M, Matthews, Q L, Icyuz, M, Hooijberg, E, Dmitriev, I, Curiel, D T, de Gruijl, T D & van de Ven, R 2018, ' Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs ', Vaccines, vol. 6, no. 3 . https://doi.org/10.3390/vaccines6030042
To mount a strong anti-tumor immune response, non T cell inflamed (cold) tumors may require combination treatment encompassing vaccine strategies preceding checkpoint inhibition. In vivo targeted delivery of tumor-associated antigens (TAA) to dendrit
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
King, L A, Lameris, R, de Gruijl, T D & van der Vliet, H J 2018, ' CD1d-Invariant Natural Killer T Cell-Based Cancer Immunotherapy : α-Galactosylceramide and Beyond ', Frontiers in Immunology, vol. 9, 1519 . https://doi.org/10.3389/fimmu.2018.01519
Frontiers in Immunology
King, L A, Lameris, R, de Gruijl, T D & van der Vliet, H J 2018, ' CD1d-Invariant Natural Killer T Cell-Based Cancer Immunotherapy : α-Galactosylceramide and Beyond ', Frontiers in Immunology, vol. 9, 1519 . https://doi.org/10.3389/fimmu.2018.01519
Frontiers in Immunology
CD1d-restricted invariant natural killer T (iNKT) cells are considered an attractive target for cancer immunotherapy. Upon their activation by glycolipid antigen and/or cytokines, iNKT cells can induce direct lysis of tumor cells but can also induce
Autor:
Kristina Lundberg, Shahram Kordasti, Nathalie van Leeuwen-Kerkhoff, Tanja D. de Gruijl, Arjan A. van de Loosdrecht, Malin Lindstedt, Hetty J. Bontkes, Theresia M. Westers
Publikováno v:
Frontiers in Immunology
van Leeuwen-Kerkhoff, N, Lundberg, K, Westers, TM, Kordasti, S, Bontkes, HJ, Lindstedt, M, de Gruijl, TD & van de Loosdrecht, AA 2018, ' Human Bone Marrow-Derived Myeloid Dendritic Cells Show an Immature Transcriptional and Functional Profile Compared to Their Peripheral Blood Counterparts and Separate from Slan+ Non-Classical Monocytes ', Frontiers in Immunology, vol. 9, no. 1619 . https://doi.org/10.3389/fimmu.2018.01619
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9(1619). Frontiers Media S.A.
van Leeuwen-Kerkhoff, N, Lundberg, K, Westers, TM, Kordasti, S, Bontkes, HJ, Lindstedt, M, de Gruijl, TD & van de Loosdrecht, AA 2018, ' Human Bone Marrow-Derived Myeloid Dendritic Cells Show an Immature Transcriptional and Functional Profile Compared to Their Peripheral Blood Counterparts and Separate from Slan+ Non-Classical Monocytes ', Frontiers in Immunology, vol. 9, no. 1619 . https://doi.org/10.3389/fimmu.2018.01619
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9(1619). Frontiers Media S.A.
The human bone marrow (BM) gives rise to all distinct blood cell lineages, including CD1c+ (cDC2) and CD141+ (cDC1) myeloid dendritic cells (DC) and monocytes. These cell subsets are also present in peripheral blood (PB) and lymphoid tissues. However
Autor:
A. Marijne Heeren, Ilse van Dijk, Daniella R. A. I. Berry, Maryam Khelil, Debbie Ferns, Jeroen Kole, René J. P. Musters, Victor L. Thijssen, Constantijne H. Mom, Gemma G. Kenter, Maaike C. G. Bleeker, Tanja D. de Gruijl, Ekaterina S. Jordanova
Publikováno v:
Frontiers in Immunology, 9(JUL):1598. Frontiers Media S.A.
Heeren, A M, van Dijk, I, Berry, D R A I, Khelil, M, Ferns, D, Kole, J, Musters, R J P, Thijssen, V L, Mom, C H, Kenter, G G, Bleeker, M C G, de Gruijl, T D & Jordanova, E S 2018, ' Indoleamine 2,3-dioxygenase expression pattern in the tumor microenvironment predicts clinical outcome in early stage cervical cancer ', Frontiers in Immunology, vol. 9, no. JUL, 1598 . https://doi.org/10.3389/fimmu.2018.01598
Frontiers in Immunology
Frontiers in immunology, 9(JUL):1598. Frontiers Media S.A.
Frontiers in Immunology, Vol 9 (2018)
Heeren, A M, van Dijk, I, Berry, D R A I, Khelil, M, Ferns, D, Kole, J, Musters, R J P, Thijssen, V L, Mom, C H, Kenter, G G, Bleeker, M C G, de Gruijl, T D & Jordanova, E S 2018, ' Indoleamine 2,3-dioxygenase expression pattern in the tumor microenvironment predicts clinical outcome in early stage cervical cancer ', Frontiers in Immunology, vol. 9, no. JUL, 1598 . https://doi.org/10.3389/fimmu.2018.01598
Frontiers in Immunology
Frontiers in immunology, 9(JUL):1598. Frontiers Media S.A.
Frontiers in Immunology, Vol 9 (2018)
The indoleamine 2,3-dioxygenase (IDO) enzyme can act as an immunoregulator by inhibiting T cell function via the degradation of the essential amino acid tryptophan (trp) into kynurenine (kyn) and its derivates. The kyn/trp ratio in serum is a prognos
Autor:
Marjon Al, Tanja D. de Gruijl, Rik J. Scheper, Janet L. Anderl, Gerrit Jansen, Ben A. C. Dijkmans, Willem F Lems, Rieneke van de Ven, Henk M.W. Verheul, Elena T. Chan, Henk L. Dekker, Sue Ellen Verbrugge
Publikováno v:
Journal of Molecular and Clinical Medicine, 1(1):DOI: 10.31083/j.jmcm.2018.01.005, 37-46
van de Ven, R, Verbrugge, S E, Al, M, Dekker, H, Verheul, HMW, Anderl, J L, Chan, E T, Dijkmans, BAC, Lems, WF, Scheper, RJ, Jansen, G & de Gruijl, TD 2018, ' Enhanced Dendritic Cell Development Through Long-Term Proteasome Inhibition ', Journal of Molecular and Clinical Medicine, vol. 1, no. 1, DOI: 10.31083/j.jmcm.2018.01.005, pp. 37-46 .
van de Ven, R, Verbrugge, S E, Al, M, Dekker, H, Verheul, HMW, Anderl, J L, Chan, E T, Dijkmans, BAC, Lems, WF, Scheper, RJ, Jansen, G & de Gruijl, TD 2018, ' Enhanced Dendritic Cell Development Through Long-Term Proteasome Inhibition ', Journal of Molecular and Clinical Medicine, vol. 1, no. 1, DOI: 10.31083/j.jmcm.2018.01.005, pp. 37-46 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b54af2e19e32023a49c0b2e19af2f9
https://research.vumc.nl/en/publications/e5f0b6f0-e243-4851-8b8d-9f01b7bc3e2c
https://research.vumc.nl/en/publications/e5f0b6f0-e243-4851-8b8d-9f01b7bc3e2c
Autor:
Rieneke van de Ven, Tiffany C. Blair, Rom Leidner, Marka R. Crittenden, Tanja D. de Gruijl, David J. Friedman, Shelly Bambina, Yaping Wu, Michael J. Gough, Jason R. Baird, Terry R. Medler, Zhaoyu Sun, Gwen Kramer, R. Bryan Bell, Victoria Troesch
Publikováno v:
Baird, J R, Bryan Bell, R, Troesch, V, Friedman, D, Bambina, S, Kramer, G, Blair, T C, Medler, T, Wu, Y, Sun, Z, de Gruijl, T D, van de Ven, R, Leidner, R S, Crittenden, M R & Gough, M J 2018, ' Evaluation of explant responses to STING ligands: Personalized immunosurgical therapy for head and neck squamous cell carcinoma ', Cancer Research, vol. 78, no. 21, pp. 6308-6319 . https://doi.org/10.1158/0008-5472.CAN-18-1652
Cancer Research, 78(21), 6308-6319. American Association for Cancer Research Inc.
Cancer Research, 78(21), 6308-6319. American Association for Cancer Research Inc.
Surgeons have unique in situ access to tumors enabling them to apply immunotherapies to resection margins as a means to prevent local recurrence. Here, we developed a surgical approach to deliver stimulator of interferon genes (STING) ligands to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7508ffb1e749659e9c47c89c72a5fdb
https://research.vumc.nl/en/publications/63a98368-5257-4df4-94f3-ee309ecc134c
https://research.vumc.nl/en/publications/63a98368-5257-4df4-94f3-ee309ecc134c