Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sumiti Vinayak"'
Autor:
Mohammad Zeeshan, Mohammad Tauqeer Alam, Sumiti Vinayak, Hema Bora, Rupesh Kumar Tyagi, Mohd Shoeb Alam, Vandana Choudhary, Pooja Mittra, Vanshika Lumb, Praveen Kumar Bharti, Venkatachalam Udhayakumar, Neeru Singh, Vidhan Jain, Pushpendra Pal Singh, Yagya Dutta Sharma
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43430 (2012)
RTS,S is the most advanced malaria vaccine candidate, currently under phase-III clinical trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region and the complete C-terminal T cell epitope region (Th2R and Th3R)
Externí odkaz:
https://doaj.org/article/e93356ca7e9d4fa895a299418020c96b
Autor:
Sumiti Vinayak, Derek J. Pinto
Publikováno v:
Current Clinical Microbiology Reports
Purpose of Review Cryptosporidium spp. (C. hominis and C. parvum) are a major cause of diarrhea-associated morbidity and mortality in young children globally. While C. hominis only infects humans, C. parvum is a zoonotic parasite that can be transmit
Autor:
Sumiti Vinayak
Publikováno v:
Curr Opin Microbiol
Cryptosporidium is a leading cause of diarrhea-associated morbidity and mortality in young children. Currently, there is no fully effective drug to treat cryptosporidiosis and a complete lack of vaccine to prevent disease. For a long time, progress i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1dd68eea13444f26cb7ec429ad91e40
https://europepmc.org/articles/PMC7746576/
https://europepmc.org/articles/PMC7746576/
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
mBio
mBio
Cryptosporidium parvum and Cryptosporidium hominis are leading pathogens responsible for diarrheal disease (cryptosporidiosis) and deaths in infants and children below 5 years of age. There are no effective treatment options and no vaccine for crypto
Autor:
Yael Bar-Peled, Caleb J. Studstill, Adam Sateriale, Sumiti Vinayak, Boris Striepen, Mattie C. Pawlowic, Carrie F. Brooks, Michael J. Cipriano
Publikováno v:
Nature
Recent studies into the global causes of severe diarrhoea in young children have identified the protozoan parasite Cryptosporidium as the second most important diarrhoeal pathogen after rotavirus. Diarrhoeal disease is estimated to be responsible for
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection
Autor:
Erkang Fan, Kayode K. Ojo, Molly C. McCloskey, Sumiti Vinayak, Wesley C. Van Voorhis, Dustin J. Maly, Matthew A. Hulverson, Rama Subba Rao Vidadala, Wenlin Huang, Lynn K. Barrett, Boris Striepen, Ryan Choi, Deborah A. Schaefer, Grant R. Whitman, Samuel L.M. Arnold, Michael W. Riggs
Publikováno v:
The Journal of Infectious Diseases
Summary Physiologically based pharmacokinetic models for bumped kinase inhibitors suggest that in vivo anticryptosporidial efficacy is associated with gastrointestinal concentrations of drug.
There is a substantial need for novel therapeutics to
There is a substantial need for novel therapeutics to
Autor:
Thierry T. Diagana, Suresh B. Lakshminarayana, Susan Noh, Francesca Blasco, Carrie F. Brooks, Jennifer A. Zambriski, Laura B. Goodman, Gu Feng, Sumiti Vinayak, Gillian T. Herbert, Peter Gedeck, Lijun Zhang, Jayesh Tandel, Siau H. Lim, Christian G. Noble, F. Joel Leong, Alex Chao, Juergen Wagner, Bin Zou, Boris Striepen, Tracy Sy, Ravinder Reddy Kondreddi, Christophe Bodenreider, Ujjini H. Manjunatha, Ghislain M. C. Bonamy, Adam Sateriale
Publikováno v:
Nature
Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a leading cause of paediatric diarrhoea, with particularly grave impact on infants and immunocompr
Autor:
Kami Kim, Elena S. Suvorova, Li Min Ting, Joshua B. Radke, Michael W. White, Boris Striepen, Stella Kratzer, Sumiti Vinayak, Carmelo A. Alvarez
Publikováno v:
Molecular Microbiology. 90:338-355
Apicomplexa division involves several distinct phases shared with other eukaryote cell cycles including a gap period (G1) prior to chromosome synthesis, although how progression through the parasite cell cycle is controlled is not understood. Here we
Publikováno v:
Malaysian Orthopaedic Journal
Malaysian Orthopaedic Journal, Vol 7, Iss 2, Pp 1-5 (2013)
Malaysian Orthopaedic Journal, Vol 7, Iss 2, Pp 1-5 (2013)
Introduction:Supracondylar fracture of the humerus is a common injury in children. It accounts for 60% of fractures around the elbow children. If the fracture is not treated properly it may give rise to many complications like malunion, Volkmann’s
Autor:
Venkatachalam Udhayakumar, Sean M. Griffing, John W. Barnwell, Tauqeer Alam, Nancy O. Duah, Anita Ghansah, Laurence Slutsker, Sumiti Vinayak, Michael D. Wilson, Amanda Poe, Dziedzom K. de Souza, Kwadwo A. Koram, Kwame Asamoa
Publikováno v:
The Journal of Infectious Diseases. 203:220-227
Background. In 2005, Ghana adopted artemisinin-based combination therapy (ACT) for primary treatment of falciparum malaria. A comprehensive study of the drug-resistance–associated mutations and their genetic lineages will lead to a better understan