Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Ryo, Ito"'
Autor:
Yuki Ono, Ryo Ito, Kaito Arai, Gurdeep Singh, Tsuyoshi Saitoh, Robert B. Russell, Francesco Raimondi, Junken Aoki, Juro Sakai, Asuka Inoue
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/2dd83316b56b4837ab140d0eb22252e2
Autor:
Ryo Ito, Azuma Kimura, Yurie Hirose, Yu Hatano, Atsushi Mima, Shin-Ichi Mae, Yamato Keidai, Toshihiro Nakamura, Junji Fujikura, Yohei Nishi, Akira Ohta, Taro Toyoda, Nobuya Inagaki, Kenji Osafune
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract For pluripotent stem cell (PSC)-based regenerative therapy against diabetes, the differentiation efficiency to pancreatic lineage cells needs to be improved based on the mechanistic understanding of pancreatic differentiation. Here, we aimed
Externí odkaz:
https://doaj.org/article/df2cb19d80214e9ca8bdf82af4846cfd
Autor:
Hideyuki Hiyoshi, Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Shinya Asano, Taisuke Mochida, Junji Yamaura, Shuhei Konagaya, Ryo Fujii, Hirokazu Matsumoto, Ryo Ito, Taro Toyoda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The differentiation of pancreatic endocrine cells from human pluripotent stem cells has been thoroughly investigated for their application in cell therapy against diabetes. Although non-endocrine cells are inevitable contaminating by-product
Externí odkaz:
https://doaj.org/article/230766f713d141caa8dc083eae065981
Autor:
Ryo Suenaga, Shuhei Konagaya, Junji Yamaura, Ryo Ito, Satoshi Tanaka, Yoichi Ishizaki, Taro Toyoda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Pluripotent stem-cell derived cells can be used for type I diabetes treatment, but we require at least 105–106 islet-like clusters per patient. Although thousands of uniform cell clusters can be produced using a conventional microwell plat
Externí odkaz:
https://doaj.org/article/f8192a40b43144d49be1ffed9ba38ecb
Autor:
Hiroki Sakamoto, Koji Miyanishi, Shingo Tanaka, Ryo Ito, Kota Hamaguchi, Akira Sakurada, Masanori Sato, Tomohiro Kubo, Takahiro Osuga, Kazuyuki Murase, Kohichi Takada, Yusaku Nakabeppu, Masayoshi Kobune, Junji Kato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Non-alcoholic steatohepatitis (NASH)-related HCC is associated with oxidative stress. However, the mechanisms underlying the development of NASH-related HCC is unclear. MUTYH is one of the enzymes that is involved in repair of oxidative DNA
Externí odkaz:
https://doaj.org/article/69299cb1a36c415897cf85463ac68c38
Autor:
Nobumasa Ohara, Michi Kobayashi, Kazumasa Ohashi, Ryo Ito, Yohei Ikeda, Gen Kawaguchi, Yuichiro Yoneoka, Go Hasegawa, Toshinori Takada
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-10 (2019)
Abstract Introduction Immune checkpoint inhibitors are a promising class of anticancer drugs. The clinical benefits afforded by immune checkpoint inhibitors can be accompanied by immune-related adverse events that affect multiple organs, and endocrin
Externí odkaz:
https://doaj.org/article/7a68d7525c024e51a0bf45ac45aed200
Autor:
Hikaru Ueno, Ryo Ito, Shin-Ichi Abe, Hitomi Ogino, Minoru Maruyama, Hirohisa Miyashita, Yasufumi Miyamoto, Yusuke Moritoh, Yoshiyuki Tsujihata, Koji Takeuchi, Nobuhiro Nishigaki
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222653 (2019)
GPR40/FFAR1 is a Gq protein-coupled receptor expressed in pancreatic β cells and enteroendocrine cells, and mediates insulin and incretin secretion to regulate feeding behavior. Several GPR40 full agonists have been reported to reduce food intake in
Externí odkaz:
https://doaj.org/article/8b8c641e5d7b42ad9c100d8692af4d44
Autor:
Takahiro Osuga, Ryo Ito, Hiroyuki Ohnuma, Kota Hamaguchi, Shingo Tanaka, Koji Miyanishi, Yusuke Sugama, Kazuyuki Murase, Masayoshi Kobune, Hiroki Sakamoto, Kohich Takada, Tomohiro Kubo, Junji Kato
Publikováno v:
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
JGH Open, Vol 5, Iss 12, Pp 1335-1343 (2021)
JGH Open, Vol 5, Iss 12, Pp 1335-1343 (2021)
Background and Aim Reliable predictors for hepatocellular carcinoma (HCC) are urgently needed. The psoas muscle index (PMI) is a simple and rapid method for evaluating muscle atrophy. Furthermore, the neutrophil/lymphocyte ratio (NLR) is a prognostic
Autor:
Yoshio Kobayashi, Miyo Nakano, Yusuke Kondo, Ryo Ito, Haruhiro Takahira, Masahiro Nakano, Toshinori Chiba, Takatsugu Kajiyama, Mari Kitagawa, Masafumi Sugawara
Publikováno v:
Journal of Cardiology. 78:362-367
It is unclear whether there is any difference in the background and prognosis between non-elderly patients who undergo catheter ablation of atrial fibrillation (AF) and common atrial flutter (CAFL).To investigate the difference between the patient ba
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Vol 8, Iss 6, Pp 5572-5576 (2021)
ESC Heart Failure, Vol 8, Iss 6, Pp 5572-5576 (2021)
Fulminant myocarditis is an inflammatory disease of the cardiac muscle that severely deteriorates cardiac function and often causes haemodynamic collapse in a manner similar to acute coronary syndrome. In rare cases, the myocardium of the right ventr