Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ron Stewart"'
Autor:
Huishi Toh, Alexander Smolentsev, Ryan Sadjadi, Dennis Clegg, Jingqi Yan, Ron Stewart, James A. Thomson, Peng Jiang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Diabetic retinopathy is a common complication of long-term diabetes and that could lead to vision loss. Unfortunately, early diabetic retinopathy remains poorly understood. There is no effective way to prevent or treat early diabetic retinop
Externí odkaz:
https://doaj.org/article/1ff3aa6970d04b85a6a12d12ef905b42
Autor:
Ian Ross, John Steill, James Thomson, Miron Livny, David Page, Finn Kuusisto, Ron Stewart, Daniel Ng
Publikováno v:
F1000Research, Vol 9 (2021)
Many important scientific discoveries require lengthy experimental processes of trial and error and could benefit from intelligent prioritization based on deep domain understanding. While exponential growth in the scientific literature makes it diffi
Externí odkaz:
https://doaj.org/article/a6867958572446248f298ded7ad990c1
Autor:
Morten Seirup, Li-Fang Chu, Srikumar Sengupta, Ning Leng, Hadley Browder, Kevin Kapadia, Christina M Shafer, Bret Duffin, Angela L Elwell, Jennifer M Bolin, Scott Swanson, Ron Stewart, Christina Kendziorski, James A Thomson, Rhonda Bacher
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239711 (2020)
As newer single-cell protocols generate increasingly more cells at reduced sequencing depths, the value of a higher read depth may be overlooked. Using data from three different single-cell RNA-seq protocols that lend themselves to having either high
Externí odkaz:
https://doaj.org/article/653545f9595e443993e4a86848c2c3b4
Autor:
Susanne Meyer, John P Maufort, Jeff Nie, Ron Stewart, Brian E McIntosh, Lisa R Conti, Kareem M Ahmad, H Tom Soh, James A Thomson
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71798 (2013)
DNA aptamers generated by cell-SELEX offer an attractive alternative to antibodies, but generating aptamers to specific, known membrane protein targets has proven challenging, and has severely limited the use of aptamers as affinity reagents for cell
Externí odkaz:
https://doaj.org/article/bbbcd9c73b094188b31a3d763ca8b52a
Autor:
Sapna Kumari, Jeff Nie, Huann-Sheng Chen, Hao Ma, Ron Stewart, Xiang Li, Meng-Zhu Lu, William M Taylor, Hairong Wei
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50411 (2012)
BACKGROUND: Constructing coexpression networks and performing network analysis using large-scale gene expression data sets is an effective way to uncover new biological knowledge; however, the methods used for gene association in constructing these c
Externí odkaz:
https://doaj.org/article/0b383d0de9014bdea1be451a93ef24fd
Autor:
Finn Kuusisto, Danielle A. Scholze, Arezoo Movaghar, Murray H. Brilliant, Ron Stewart, Leann Smith DaWalt, David C. Page, Marsha R. Mailick, Jinkuk Hong
Publikováno v:
Genetics in Medicine
Purpose Fragile X syndrome (FXS), the most prevalent inherited cause of intellectual disability, remains underdiagnosed in the general population. Clinical studies have shown that individuals with FXS have a complex health profile leading to unique c
Autor:
Matthew N. Bernstein, Mark E. Burkard, Zijian Ni, Michael Collins, Ron Stewart, Christina Kendziorski
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-9 (2021)
BMC Bioinformatics
BMC Bioinformatics
Background Single-cell RNA-seq (scRNA-seq) enables the profiling of genome-wide gene expression at the single-cell level and in so doing facilitates insight into and information about cellular heterogeneity within a tissue. This is especially importa
Autor:
Brian Johnson, Gregory A. Barrett-Wilt, Srikumar Sengupta, Bret Duffin, Ron Stewart, Hamisha Ardalani, James A. Thomson, Morten Seirup
Publikováno v:
Current Research in Toxicology
Current Research in Toxicology, Vol 1, Iss, Pp 70-84 (2020)
Current Research in Toxicology, Vol 1, Iss, Pp 70-84 (2020)
Derivation and culture of small hepatocyte progenitor cells (SHPCs) capable of proliferating in vitro has been described in rodents and recently in humans. These cells are capable of engrafting in injured livers, however, they display de-differentiat
Autor:
Michael P. Schwartz, Amy Van Aartsen, Christina Kendziorski, Cara Argus, Matthew T. Schmitz, Christopher Barry, Scott Swanson, Jared Brown, Ron Stewart, James A. Thomson, Jennifer M. Bolin, John Steill
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 3, p e1008778 (2021)
PLoS Computational Biology, Vol 17, Iss 3, p e1008778 (2021)
Human pluripotent stem cells hold significant promise for regenerative medicine. However, long differentiation protocols and immature characteristics of stem cell-derived cell types remain challenges to the development of many therapeutic application
Autor:
Jennifer M. Bolin, Parker Knight, Cara Argus, James A. Thomson, Christina Kendziorski, Ron Stewart, Li-Fang Chu, Rhonda Bacher
Publikováno v:
Nucleic Acids Research
Considerable effort has been devoted to refining experimental protocols to reduce levels of technical variability and artifacts in single-cell RNA-sequencing data (scRNA-seq). We here present evidence that equalizing the concentration of cDNA librari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9277d63a70486cef35bf214346d5048
https://doi.org/10.1101/2020.10.05.326553
https://doi.org/10.1101/2020.10.05.326553