Zobrazeno 1 - 10
of 17 002
pro vyhledávání: '"Mice, Inbred C3H"'
Autor:
Takashi Shimokawa, Takashi Imai, Akihisa Takahashi, Tsuguhide Takeshima, Hiromi Otsuka, Ken Ando, Liqiu Ma, Kazuhiro Kakimi, Yoshimitsu Sakamoto, Daniel K. Ebner, Hidetoshi Fujita
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:780-789
Purpose: The goal of this study is to clarify the underlying mechanisms of metastasis suppression by CiDC (carbon-ion radiotherapy (CIRT) combined with immature dendritic cell (iDC) immunotherapy), which was previously shown to significantly suppress
Autor:
Gib Bogle, William R. Wilson, Michael P. Hay, Praju Vikas Anekal, Kevin O. Hicks, Benjamin D. Dickson, Way W. Wong, Chantal D. Buckley, Cho R. Hong
Publikováno v:
Radiotherapy and Oncology. 166:162-170
Background and purpose Inhibitors of DNA-dependent protein kinase (DNA-PK) are effective radiation sensitisers in preclinical tumours, but little is known about risks of normal tissue radiosensitisation. Here, we evaluate radiosensitisation of head a
Autor:
Adam Williams, Stephanie C. Eisenbarth, Lan Xu, Biyan Zhang, Lauren L. Long, Jake A. Gertie, Laura R. Hoyt, Uthaman Gowthaman, Xiangyun Yin, Elise G. Liu, Arielle Soldatenko
Publikováno v:
J Allergy Clin Immunol
Background The etiology of food allergy is poorly understood; mouse models are powerful systems to discover immunologic pathways driving allergic disease. C3H/HeJ mice are a widely used model for the study of peanut allergy because, unlike C57BL/6 or
Publikováno v:
Japanese Journal of Radiology. 40:466-475
PURPOSE Although the mechanism of onset and progression of radiation-induced fibrosis (RIF) has been studied, most studies to date have focused on pulmonary fibrosis. There are few studies on murine RIF in the skeletal muscle, and the pathogenic mech
Publikováno v:
Am J Transplant
Chronic rejection is among the most pressing clinical challenges in solid organ transplantation. Interestingly, in a mouse model of heterotopic heart transplantation, antibody-dependent, natural killer (NK) cell-mediated chronic cardiac allograft vas
Autor:
Xiao-Hong Xu, Xi Zha
Publikováno v:
Cellular and Molecular Life Sciences. 78:7289-7307
Individuals of many species fight with conspecifics to gain access to or defend critical resources essential for survival and reproduction. Such intraspecific fighting is evolutionarily selected for in a species-, sex-, and environment-dependent mann
Autor:
Toshinori Tsukanishi, Tsukasa Yonemoto, Hiroto Kamoda, Hideyuki Kinoshita, Takeshi Ishii, Yoko Hagiwara, Osamu Shimozato, Seiji Ohtori
Publikováno v:
Anticancer Research. 41:4947-4955
Background/aim Auranofin (AUR), a thioredoxin reductase (TXNRD) inhibitor, shows anticancer activity against several cancers. This study investigated the effects of AUR on the local progression and pulmonary metastasis of osteosarcoma (OS). Materials
Autor:
Chang-Yun Cho, Isaac Park, Ji Seul Han, Jee Hyung Sohn, Yong Geun Jeon, Sangsoo Lim, Hyun-Woo Rhee, Sang Mun Han, Hahn Nahmgoong, Sun Kim, Yul Ji, Jae Bum Kim
Publikováno v:
Diabetes. 70:2756-2770
Reactive oxygen species (ROS) are associated with various roles of brown adipocytes. Glucose-6-phosphate dehydrogenase (G6PD) controls cellular redox potentials by producing NADPH. Although G6PD upregulates cellular ROS levels in white adipocytes, th
Autor:
Kazuhisa Uchiyama, Emi Yasuda, Yuro Shibayama, Takahiro Kubota, Nobuhiko Tanigawa, Ryotaro Yoshida, Michihiro Hayashi, Yoshinobu Hirose, Hidenori Yamana
Publikováno v:
Journal of Interferon & Cytokine Research. 41:310-318
Graft-versus-host disease (GVHD) is a physiological response of the graft to allogeneic hosts. However, the effector cells, affected organ(s), and cytokines in the GVHD remain controversially discussed, without having determined a particular cytotoxi
Publikováno v:
Molecular Neurobiology
Dolutegravir (DTG) is a first-line antiretroviral drug (ARV) used in combination therapy for the treatment of human immunodeficiency virus type-1 (HIV-1) infection. The drug is effective, safe, and well tolerated. Nonetheless, concerns have recently