Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Melanie Boerries"'
Autor:
Cynthia Stapornwongkul, Alexandra Nieters, Paulina Staus, Stephan Rusch, Anita Delor, Ulrich Baumann, Julius Wehrle, Melanie Boerries, Markus G. Seidel, Bodo Grimbacher, Gerhard Kindle
Publikováno v:
Journal of Health Monitoring, Vol 8, Iss 4, Pp 24-30 (2023)
Background: Patient registries are an important tool for networking medical caregivers and research, especially in the field of rare diseases. Individuals afflicted by multi-organ autoimmune diseases typically suffer from inflammation of multiple org
Externí odkaz:
https://doaj.org/article/24b4660c2fa9423a940b3d97c74997ad
Autor:
Geoffroy Andrieux, Tonmoy Das, Michaela Griffin, Jakob Straehle, Simon M. L. Paine, Jürgen Beck, Melanie Boerries, Dieter H. Heiland, Stuart J. Smith, Ruman Rahman, Sajib Chakraborty
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-34 (2023)
Abstract Background Spatiotemporal heterogeneity originating from genomic and transcriptional variation was found to contribute to subtype switching in isocitrate dehydrogenase-1 wild-type glioblastoma (GBM) prior to and upon recurrence. Fluorescence
Externí odkaz:
https://doaj.org/article/ddc7f16df4c243c3bdd8102718b49299
Autor:
Eyleen Corrales, Ella Levit-Zerdoun, Patrick Metzger, Ralf Mertes, Ariane Lehmann, Julia Münch, Steffen Lemke, Silke Kowar, Melanie Boerries
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Current therapeutic management of advanced melanoma patients largely depends on their BRAF mutation status. However, the vast heterogeneity of the tumors hampers the success of therapies targeting the MAPK/ERK pathway alone. Disse
Externí odkaz:
https://doaj.org/article/9a5a8d5277504e11882ad210e91ce9a0
Autor:
Alexander Runkel, David Braig, Balazs Bogner, Adrian Schmid, Ute Lausch, Anika Boneberg, Zacharias Brugger, Anja Eisenhardt, Jurij Kiefer, Thomas Pauli, Melanie Boerries, Hannah Fuellgraf, Konrad Kurowski, Peter Bronsert, Jutta Scholber, Anca-Ligia Grosu, Philipp Rovedo, Fabian Bamberg, Steffen Ulrich Eisenhardt, Matthias Jung
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/9c3d4a362eb149a2ba7b89748d4d86cc
Autor:
Philipp Seidel, Anne Rubarth, Kyra Zodel, Asin Peighambari, Felix Neumann, Yannick Federkiel, Hsin Huang, Rouven Hoefflin, Mojca Adlesic, Christian Witt, David J. Hoffmann, Patrick Metzger, Ralph K. Lindemann, Frank T. Zenke, Christoph Schell, Melanie Boerries, Dominik von Elverfeldt, Wilfried Reichardt, Marie Follo, Joachim Albers, Ian J. Frew
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2022)
Metastatic clear cell renal cell carcinomas (ccRCCs) are resistant to DNA-damaging chemotherapies, limiting therapeutic options for patients whose tumors are resistant to tyrosine kinase inhibitors and/or immune checkpoint therapies. Here we show tha
Externí odkaz:
https://doaj.org/article/cf8515a3861b40da82fdcd8f12d444bb
Autor:
Eyleen Corrales, Ella Levit-Zerdoun, Patrick Metzger, Silke Kowar, Manching Ku, Tilman Brummer, Melanie Boerries
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Vemurafenib (PLX4032) is one of the most frequently used treatments for late-stage melanoma patients with the BRAF V600E mutation; however, acquired resistance to the drug poses as a major challenge. It remains to be determined wh
Externí odkaz:
https://doaj.org/article/866ef96ae5834d83bcaada44126bbf7c
Autor:
Milena N. Leseva, Richard J. Grand, Hagen Klett, Melanie Boerries, Hauke Busch, Alexandra M. Binder, Karin B. Michels
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract In humans the expression of lactase changes during post-natal development, leading to phenotypes known as lactase persistence and non-persistence. Polymorphisms within the lactase gene (LCT) enhancer, in particular the −13910C > T, but als
Externí odkaz:
https://doaj.org/article/2de50f8af6c74389afa70cd5b6b411af
Autor:
Sandra Ebeling, Katrin Naumann, Simone Pollok, Tina Wardecki, Sabine Vidal-Y-Sy, Juliana M Nascimento, Melanie Boerries, Gudula Schmidt, Johanna M Brandner, Irmgard Merfort
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86147 (2014)
BACKGROUND: Birch bark has a long lasting history as a traditional medicinal remedy to accelerate wound healing. Recently, the efficacy of birch bark preparations has also been proven clinically. As active principle pentacyclic triterpenes are genera
Externí odkaz:
https://doaj.org/article/69aa1f12d4ce4290bd16032786c6c7cb
Autor:
Hauke Busch, Melanie Boerries, Jie Bao, Sebastian T Hanke, Manuel Hiss, Theodhor Tiko, Stefan A Rensing
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60494 (2013)
Transcription factors (TFs) often trigger developmental decisions, yet, their transcripts are often only moderately regulated and thus not easily detected by conventional statistics on expression data. Here we present a method that allows to determin
Externí odkaz:
https://doaj.org/article/b7818e8832e74fa28991bb61fe4234c4
Autor:
Sebastian Weber, María L Fernández-Cachón, Juliana M Nascimento, Steffen Knauer, Barbara Offermann, Robert F Murphy, Melanie Boerries, Hauke Busch
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56690 (2013)
Detection of neuronal cell differentiation is essential to study cell fate decisions under various stimuli and/or environmental conditions. Many tools exist that quantify differentiation by neurite length measurements of single cells. However, quanti
Externí odkaz:
https://doaj.org/article/8159bde366b948aaa47c6682d638fa61