Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Mallampalli, A."'
Autor:
Jiaxing Miao, Lian Li, Nargis Shaheen, Jianxin Wei, Anastasia M. Jacko, Prithu Sundd, Sarah J. Taleb, Rama K. Mallampalli, Yutong Zhao, Jing Zhao
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 395-407 (2024)
Abstract Endothelial cell (EC) barrier disruption and inflammation are the pathological hallmarks of vascular disorders and acute infectious diseases and related conditions, including the coronavirus disease 2019 (COVID-19) and sepsis. Ubiquitination
Externí odkaz:
https://doaj.org/article/7c0111ee9de4482c82adb94ab399c021
Autor:
William Bain, Mohammadreza Tabary, Sara R. Moore, Xiaojing An, Georgios D. Kitsios, Bryan J. McVerry, Prabir Ray, Anuradha Ray, Rama K. Mallampalli, Viviana P. Ferreira, Janet S. Lee, S. Mehdi Nouraie
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2023)
Background Effective regulation of complement activation may be crucial to preserving complement function during acute respiratory distress syndrome (ARDS). Factor H is the primary negative regulator of the alternative pathway of complement. We hypot
Externí odkaz:
https://doaj.org/article/3243b63a7e464800b085d884997730f5
Autor:
Haider H. Dar, Michael W. Epperly, Vladimir A. Tyurin, Andrew A. Amoscato, Tamil S. Anthonymuthu, Austin B. Souryavong, Alexander A. Kapralov, Galina V. Shurin, Svetlana N. Samovich, Claudette M. St. Croix, Simon C. Watkins, Sally E. Wenzel, Rama K. Mallampalli, Joel S. Greenberger, Hülya Bayır, Valerian E. Kagan, Yulia Y. Tyurina
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Total body irradiation (TBI) targets sensitive bone marrow hematopoietic cells and gut epithelial cells, causing their death and inducing a state of immunodeficiency combined with intestinal dysbiosis and nonproductive immune responses. We found enha
Externí odkaz:
https://doaj.org/article/064649aa63e64d92892a0366bc434be8
Autor:
Lian Li, Jianxin Wei, Shuang Li, Anastasia M. Jacko, Nathaniel M. Weathington, Rama K. Mallampalli, Jing Zhao, Yutong Zhao
Publikováno v:
EBioMedicine, Vol 45, Iss , Pp 553-562 (2019)
Background: The Single immunoglobin interleukin-1 (IL-1)-related receptor (Sigirr), also known as IL-1R8, has been shown to exhibit broad anti-inflammatory effects against inflammatory diseases including acute lung injury, while molecular regulation
Externí odkaz:
https://doaj.org/article/1fd0ba3a51754b88918b380738bf84fc
Autor:
Cong Zeng, John P. Evans, Rebecca Pearson, Panke Qu, Yi-Min Zheng, Richard T. Robinson, Luanne Hall-Stoodley, Jacob Yount, Sonal Pannu, Rama K. Mallampalli, Linda Saif, Eugene Oltz, Gerard Lozanski, Shan-Lu Liu
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
Rapid and specific antibody testing is crucial for improved understanding, control, and treatment of COVID-19 pathogenesis. Herein, we describe and apply a rapid, sensitive, and accurate virus neutralization assay for SARS-CoV-2 antibodies. The assay
Externí odkaz:
https://doaj.org/article/73c6773c662347b395a6fb3d8c4a65a5
Autor:
Xiuying Li, Tiao Li, Seyed Mehdi Nouraie, Janet S. Lee, Kong Chen, Georgios D Kitsios, Rama K. Mallampalli, Bryan J. McVerry, Yingze Zhang, Yandong Lai, Chunbin Zou, Toru Nyunoya
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Lung epithelial cell death is a prominent feature of acute lung injury and acute respiratory distress syndrome (ALI/ARDS), which results from severe pulmonary infection leading to respiratory failure. Multiple mechanisms are believed to contribute to
Autor:
Mauricio Rojas, Jia Liu, Yutong Zhao, Jing Zhao, Xinxin Liao, Rama K. Mallampalli, Yanhui Li, Yingze Zhang, Daniel J. Kass, Jiangning Tan
Publikováno v:
Transl Res
Smad4 plays a central role in the regulation of extracellular matrix (ECM) protein expression and cell differentiation; however, the molecular regulation of Smad4 protein stability by a deubiquitinase has not been reported. In the current study, we r
Autor:
Miguel Pinilla-Vera, Zeyu Xiong, Yutong Zhao, Jing Zhao, Michael P Donahoe, Suchitra Barge, William T Horne, Jay K Kolls, Bryan J McVerry, Anastasiya Birukova, Robert M Tighe, W Michael Foster, John Hollingsworth, Anuradha Ray, Rama Mallampalli, Prabir Ray, Janet S Lee
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159329 (2016)
Despite recent advances in understanding macrophage activation, little is known regarding how human alveolar macrophages in health calibrate its transcriptional response to canonical TLR4 activation. In this study, we examined the full spectrum of LP
Externí odkaz:
https://doaj.org/article/ef02527a842b489e8b337410d2604e08
Autor:
Sara R. Moore, Alison Morris, Bryan J. McVerry, Hui-Hua Li, Mehdi Nouraie, Mei Hulver, Rebecca S. DeSensi, Erin Papke, Yohei Doi, Georgios D Kitsios, Melissa Saul, William Bain, Rick van der Geest, Tolani F. Olonisakin, Prabir Ray, Rama K. Mallampalli, Viviana P. Ferreira, Yingze Zhang, Lina Ma, Brian Ahn, Sarah F. Rapport, Janet S. Lee, Hrishikesh S. Kulkarni, Zeyu Xiong, Kaveh Moghbeli
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 202:230-240
Rationale: Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which can amplify all complement a...
Autor:
Joshua A. Englert, Nicholas A Bosch, Rama K. Mallampalli, Allan J. Walkey, Yaseen M. Arabi, Hasan M. Al-Dorzi
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 201:1050-1057