Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Luis de la Cruz"'
Autor:
Natalia Palazón-Carrión, Carlos Jiménez-Cortegana, M. Luisa Sánchez-León, Fernando Henao-Carrasco, Esteban Nogales-Fernández, Massimo Chiesa, Rosalía Caballero, Federico Rojo, María-Adoración Nieto-García, Víctor Sánchez-Margalet, Luis de la Cruz-Merino, the Spanish Breast Cancer Group (GEICAM) and the Spanish Group for Immunobiotherapy of Cancer (GÉTICA)
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Identification of the different elements intervening at the tumor microenvironment seems key to explain clinical evolution in several tumor types. In this study, a set of immune biomarkers (myeloid derived suppressor cells, regulatory T cell
Externí odkaz:
https://doaj.org/article/f7ffda4053d44faa99e7001d804ed3ac
Autor:
Natalia Palazón‑Carrión, Carlos Jiménez‑Cortegana, M. Luisa Sánchez‑León, Fernando Henao‑Carrasco, Esteban Nogales‑Fernández, Massimo Chiesa, Rosalía Caballero, Federico Rojo, María‑Adoración Nieto‑García, Víctor Sánchez‑Margalet, Luis de la Cruz‑Merino, the Spanish Breast Cancer Group (GEICAM) and the Spanish Group for Immunobiotherapy of Cancer (GÉTICA)
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/7cb81409be9d4aa6a04463d97674463c
Autor:
Luis de la Cruz-Merino, Lorenza Di Guardo, Jean-Jacques Grob, Alfredo Venosa, James Larkin, Grant A. McArthur, Antoni Ribas, Paolo A. Ascierto, Jeffrey T. R. Evans, Antonio Gomez-Escobar, Giulio Barteselli, Susan Eng, Jessie J. Hsu, Anne Uyei, Brigitte Dréno
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Serous chorioretinopathy has been associated with MEK inhibitors, including cobimetinib. We describe the clinical features of serous retinopathy observed with cobimetinib in patients with BRAF V600-mutated melanoma treated in the
Externí odkaz:
https://doaj.org/article/38b41caecf344ca693b0253d6557253d
Autor:
Julia González-Rincón, Miriam Méndez, Sagrario Gómez, Juan F García, Paloma Martín, Carmen Bellas, Lucía Pedrosa, Socorro M Rodríguez-Pinilla, Francisca I Camacho, Cristina Quero, David Pérez-Callejo, Antonio Rueda, Marta Llanos, José Gómez-Codina, Miguel A Piris, Santiago Montes-Moreno, Carmen Bárcena, Delvys Rodríguez-Abreu, Javier Menárguez, Luis de la Cruz-Merino, Silvia Monsalvo, Consuelo Parejo, Ana Royuela, Ivo Kwee, Luciano Cascione, Alberto Arribas, Francesco Bertoni, Manuela Mollejo, Mariano Provencio, Margarita Sánchez-Beato
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212813 (2019)
Follicular lymphoma (FL) is an indolent but largely incurable disease. Some patients suffer histological transformation to a more aggressive subtype with poorer prognosis. This study aimed to improve our understanding of the genetics underlying FL hi
Externí odkaz:
https://doaj.org/article/98e18833736b493c8cd158af3b9d62c8
Autor:
Mariano Provencio, Pilar Sabín, Jose Gomez-Codina, Maria Torrente, Virginia Calvo, Marta Llanos, Josep Gumá, Cristina Quero, Ana Blasco, Miguel Angel Cruz, David Aguiar, Francisco García-Arroyo, Javier Lavernia, Natividad Martinez, Manuel Morales, Alvaro Saez-Cusi, Delvys Rodriguez, Luis de la Cruz, Jose Javier Sanchez, Antonio Rueda, GOTEL (Spanish Lymphoma Oncology Group)
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177204 (2017)
BACKGROUND:Follicular lymphoma is the second most common non-Hodgkin lymphoma in the United States and Europe. However, most of the prospective randomized studies have very little follow-up compared to the long natural history of the disease. The pri
Externí odkaz:
https://doaj.org/article/6e236207a74245ef906d5faa5f1d0dde
Autor:
Antonio Pérez-Pérez, Flora Sánchez-Jiménez, Teresa Vilariño-García, Luis de la Cruz, Juan A Virizuela, Víctor Sánchez-Margalet
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158218 (2016)
Obesity is a well-known risk factor for breast cancer development in postmenopausal women. High insulin and leptin levels seem to have a role modulating the growth of these tumours. Sam68 is an RNA-binding protein with signalling functions that has b
Externí odkaz:
https://doaj.org/article/c1b39d5f0e224d56919032afc04af76c
Autor:
Iván Márquez-Rodas, Manuel Martín González, Eduardo Nagore, Cristina Gómez-Fernández, Jose Antonio Avilés-Izquierdo, Cayetana Maldonado-Seral, Virtudes Soriano, Margarita Majem-Tarruella, Virginia Palomar, Rocio Maseda, Alfonso Martín-Carnicero, Teresa Puertolas, Elena Godoy, Pablo Cerezuela, Maria Ochoa de Olza, Begoña Campos, Elisabeth Perez-Ruiz, Ainara Soria, Irene Gil-Arnaiz, Maria Gonzalez-Cao, Elisa Galvez, Ana Arance, Joaquin Belon, Luis de la Cruz-Merino, Salvador Martín-Algarra, Spanish Multidisciplinary Group of Melanoma (GEM)
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124239 (2015)
INTRODUCTION:Familial history of melanoma is a well-known risk factor for the disease, and 7% melanoma patients were reported to have a family history of melanoma. Data relating to the frequency and clinical and pathological characteristics of both f
Externí odkaz:
https://doaj.org/article/0c51f99874584046b7850d8c146d4283
Autor:
Clara Mayo de las Casas, Maria Gonzalez-Cao, Sebastian Ochenduszko, Juana Oramas, Miguel Angel Molina, Eva Muñoz-Couselo, Ana Arance, Roberto Diaz Beveridge, Miguel A Berciano-Guerrero, Enrique Espinosa, Luis de la Cruz, Delvys Rodriguez, Pablo Cerezuela, Ana Drozdowskyj, L. Bellido, Clara Montagut, Teresa Puertolas, Laura Basterretxea, Jose A. Lopez-Martin, Alfonso Berrocal, Maria-Jose Villanueva, Begoña Campos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Nature Communications
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
instname
NATURE COMMUNICATIONS
r-FISABIO. Repositorio Institucional de Producción Científica
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Nature Communications
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
instname
NATURE COMMUNICATIONS
r-FISABIO. Repositorio Institucional de Producción Científica
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Combination treatment with BRAF (BRAFi) plus MEK inhibitors (MEKi) has demonstrated survival benefit in patients with advanced melanoma harboring activating BRAF mutations. Previous preclinical studies suggested that an intermittent dosing of these d
Autor:
Haocheng Li, Caroline Dutriaux, James Larkin, Edward McKenna, Claus Garbe, Luis de la Cruz-Merino, Athina Voulgari, Mario Mandalà, Paolo A. Ascierto, Lev V. Demidov, Victoria Atkinson, Brigitte Dréno, Antoni Ribas, Michele Maio, Gabriella Liszkay, Surai Jones, Luc Thomas, Jessie Hao-Ru Hsu, Grant A. McArthur, Daniil Stroyakovskiy
Publikováno v:
Clinical Cancer Research. 27:5225-5235
Purpose: The randomized phase III coBRIM study (NCT01689519) demonstrated improved progression-free survival (PFS) and overall survival (OS) with addition of cobimetinib to vemurafenib compared with vemurafenib in patients with previously untreated B
Autor:
Ignacio Miranda, Begoña Bermejo, Juan M Ferrero-Cafiero, Manel Juan, Patricia Villagrasa, Aleix Prat, Ana Delgado, Xavier Gonzalez, Maria Vidal, Tomás Pascual, Estela Vega, Ana Julve, Sergi Ganau, Juan Miguel Cejalvo, Jordi Canes, Luis de la Cruz-Merino, Mafalda Oliveira, Esther Zamora
Publikováno v:
Future Oncology. 16:1801-1813
New treatment strategies such as immune checkpoint inhibitors and oncolytic viruses are opening new possibilities in cancer therapy. Preliminary results in melanoma and other tumors showed that the combination of talimogene laherparepvec with an anti