Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristie Wood"'
Autor:
Michael J. O'Neill, David A. Collier, Alan Hodgkinson, Richard Dobson, Guillermo Carbajosa, Eva Wozniak, Hong Wang, Nathan Lawless, Angela Hodges, Stephen Newhouse, John W. Ryder, Kristie Wood, Karim Malki, Charles A. Mein
A microglia response to pathogenic signals in diseases such as Alzheimer’s disease (AD) has long been recognised, but recent genetic findings have cemented their direct causal contribution to AD and thus the potential to target them or their effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae8f3b1fabf1d01baebb27a64970fc96
https://doi.org/10.1101/2021.07.16.452732
https://doi.org/10.1101/2021.07.16.452732
Autor:
Paul Farrant, Mark Goodfield, Catherine H. Smith, V. Jolliffe, Gregory Parkins, Caroline Champagne, Lu Liu, Nigel Burrows, A. S. Bryden, Kristie Wood, Anton B. Alexandroff, Irene Man, Alka Saxena, Su M. Lwin, Iaisha Ali, Catherine M. Stefanato, Kapil Bhargava, Sang Hyuck Lee, Melanie Page, Xavier Estivill, Tim D. Spector, Carsten Flohr, Susan Holmes, David de Berker, A. E. Macbeth, Ncoza C. Dlova, David Baudry, Jake Saklatvala, Nerea Ormaechea Perez, Archana Rao, David A. Fenton, Martin S Wade, Cedric Charles Banfield, Jennifer Jones, Evangelos A A Christou, Ravinder Atkar, Gregory A Michelotti, Sergio Vano-Galvan, Seth D. Seegobin, Jane Setterfield, Jonathan Barker, Chrysanthi Ainali, Christos Tziotzios, Charles Curtis, Rashida Pramanik, Matthew Harries, Girish K Patel, Niall Kirkpatrick, Venu Pullabhatla, Fiona Cunningham, Nick Dand, Hywel L Cooper, Rodney Sinclair, Keith Armstrong, Emanuele de Rinaldis, Andrew J. G. McDonagh, M R Kaur, Fiona Lewis, Michael A. Simpson, John A. McGrath, Charles E. Mitchell, Nicola Cooke, Fiona M. Watt, Alexandros Onoufriadis, Michael R. Ardern-Jones, Tee-Wei Siah, Ioulios Palamaras, Ana María Molina-Ruiz, Megan Mowbray, A. Takwale, Andrew G. Messenger, Giles Dunnill, Christos Petridis, Shyamal Wahie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T-W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Nature Communications
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T-W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite a dramatic recent increase in incidence the aetiopathogenesis of FFA remains unknown. We undertake genome
Autor:
Kristie Wood, Kulvinder Lall, Alison M. Thomas, Malcolm Finlay, Muriel Nobles, Andrew Tinker, Charles A. Mein, Michael R. Barnes, Richard J. Schilling, Patricia B. Munroe, Claudia P. Cabrera
Publikováno v:
Physiol Genomics
Atrial fibrillation is a significant worldwide contributor to cardiovascular morbidity and mortality. Few studies have investigated the differences in gene expression between the left and right atrial appendages, leaving their characterization largel
Autor:
Pierre Bourdely, Pierre Guermonprez, Alka Saxena, Giorgio Anselmi, Julie Helft, Kristie Wood, Florent Ginhoux, Kristine Vaivode, Oliver Hickman, Yoann Missolo-Koussou, Charles-Antoine Dutertre, Evan W. Newell
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2054. ⟨10.1038/s41467-020-15937-y⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-15937-y⟩
Nature Communications, 2020, 11 (1), pp.2054. ⟨10.1038/s41467-020-15937-y⟩
Anselmi, G, Vaivode, K, Dutertre, C A, Bourdely, P, Missolo-Koussou, Y, Newell, E, Hickman, O, Wood, K, Saxena, A, Helft, J, Ginhoux, F & Guermonprez, P 2020, ' Engineered niches support the development of human dendritic cells in humanized mice ', Nature Communications, vol. 11, 2054 . https://doi.org/10.1038/s41467-020-15937-y
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2054. ⟨10.1038/s41467-020-15937-y⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-15937-y⟩
Nature Communications, 2020, 11 (1), pp.2054. ⟨10.1038/s41467-020-15937-y⟩
Anselmi, G, Vaivode, K, Dutertre, C A, Bourdely, P, Missolo-Koussou, Y, Newell, E, Hickman, O, Wood, K, Saxena, A, Helft, J, Ginhoux, F & Guermonprez, P 2020, ' Engineered niches support the development of human dendritic cells in humanized mice ', Nature Communications, vol. 11, 2054 . https://doi.org/10.1038/s41467-020-15937-y
Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive immunity. Modeling cDC development is crucial to study cDCs and harness their therapeutic potential. Here we address whether cDCs could differentiate i
Autor:
Guillermo Carbajosa, Nathan Lawless, Eva Wozniak, Karim Malki, Angela Hodges, Richard Dobson, Kristie Wood, Stephen Newhouse, Hong Wang, John W. Ryder, Michael J. O'Neill, David A. Collier, Charles A. Mein
Publikováno v:
Carbajosa, G, Malki, K, Lawless, N, Wang, H, Ryder, J W, Wozniak, E, Wood, K, Mein, C A, Dobson, R J B, Collier, D A, O'Neill, M J, Hodges, A K & Newhouse, S J 2018, ' Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain ', Neurobiology of Aging, vol. 69, pp. 151-166 . https://doi.org/10.1016/j.neurobiolaging.2018.04.019
Rare heterozygous coding variants in the Triggering Receptor Expressed in Myeloid cells 2 (TREM2) gene, conferring increased risk of developing late-onset Alzheimer's disease, have been identified. We examined the transcriptional consequences of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ee80debee5a3d95c02ee277c9de126
https://kclpure.kcl.ac.uk/ws/files/101828997/Loss_of_Trem2_in_Carbajosa_2018_GOLD_VoR.pdf
https://kclpure.kcl.ac.uk/ws/files/101828997/Loss_of_Trem2_in_Carbajosa_2018_GOLD_VoR.pdf
Publikováno v:
BMC Women's Health
Background Vitamin D status is a key determinant of maternal and neonatal health. Deficiency has been reported to be common in Pakistani women, but information regarding environmental and genetic determinants of vitamin D status is lacking in this po
Autor:
Kristie Wood, Tahir Saeed, Kashaf Junaid, Abdul Rehman, David A. Jolliffe, Adrian R. Martineau
Publikováno v:
BMC Infectious Diseases
Background Both vitamin D deficiency and genetic variants in the vitamin D receptor (VDR) have been reported to associate with delayed response to intensive-phase therapy for pulmonary tuberculosis. Studies investigating the influence of genetic vari