Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Kristian Unger"'
Autor:
Agata Michna, Herbert Braselmann, Martin Selmansberger, Anne Dietz, Julia Hess, Maria Gomolka, Sabine Hornhardt, Nils Blüthgen, Horst Zitzelsberger, Kristian Unger
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160791 (2016)
Gene expression time-course experiments allow to study the dynamics of transcriptomic changes in cells exposed to different stimuli. However, most approaches for the reconstruction of gene association networks (GANs) do not propose prior-selection ap
Externí odkaz:
https://doaj.org/article/7f377c631845469786fbbe8499ead4fe
Autor:
Corina Penterling, Guido A Drexler, Claudia Böhland, Ramona Stamp, Christina Wilke, Herbert Braselmann, Randolph B Caldwell, Judith Reindl, Stefanie Girst, Christoph Greubel, Christian Siebenwirth, Wael Y Mansour, Kerstin Borgmann, Günther Dollinger, Kristian Unger, Anna A Friedl
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156599 (2016)
Histone demethylases have recently gained interest as potential targets in cancer treatment and several histone demethylases have been implicated in the DNA damage response. We investigated the effects of siRNA-mediated depletion of histone demethyla
Externí odkaz:
https://doaj.org/article/adfdc5643a5843b8961e775bc739a89c
Autor:
Mattis Bertlich, Friedrich Ihler, Jennifer L. Spiegel, Kristian Unger, Stefan Küffer, Frank Haubner, Bernhard G. Weiss, Martin Canis, Julia Kitz, Julia Hess, Mahalia Zoe Anczykowski, Mark Jakob
Publikováno v:
Cancer Biomarkers. 33:331-347
BACKGROUND: MicroRNAs constitute promising biomarkers. OBJECTIVE: The aim was to investigate diagnostic and prognostic implications of miR-182-5p and miR-205-5p in p16-positive and p16-negative oropharyngeal squamous cell carcinomas (OPSCCs). METHODS
Autor:
Stefan Kueffer, Bernhard G. Weiss, Friedrich Ihler, Jennifer L. Spiegel, Kristian Unger, Mark Jakob, Lena M. Mattes, Julia Hess, Julia Kitz, Martin Canis, Frank Haubner, Markus D. Schirmer
Publikováno v:
Head & Neck. 43:3707-3719
Background The prognostic impact of hsa-miRNA-182-5p in oral cancer remains unexplored. Therefore, the aim of this study was to investigate the prognostic value of hsa-miRNA-182-5p and its predicted target kinectin 1 (KTN1) in oral squamous cell carc
Autor:
S. Tapio, Gerhild Wildner, Stephan R. Thurau, Kristian Unger, Florian Wagner, Andreas Beyerlein, Jochen Graw, Claudia Dalke, Horst Zitzelsberger, Ute Rößler, Fabian J. Theis, Jerzy Adamski, Andreas Ohlmann, Sarah Kunze, Gabriele Möller, Cornelia Prehn, Sabine M. Hölter, Ulrike Kulka, Alexander Cecil
Publikováno v:
Int. J. Radiat. Biol. 97, 529-540 (2021)
PURPOSE: The long-term effect of low and moderate doses of ionizing radiation on the lens is still a matter of debate and needs to be evaluated in more detail. MATERIAL AND METHODS: We conducted a detailed histological analysis of eyes from B6C3F1 mi
Autor:
Mechthild Krause, Jürgen Debus, Henning Schäfer, Bouchra Tawk, Maja Guberina, Sebastian Adeberg, Ingeborg Tinhofer, Karim Zaoui, Martin Stuschke, Steffi Pigorsch, Volker Budach, Julia Hess, Kristian Unger, Thomas Kirchner, Claus Rödel, Esther Herpel, Stephanie E. Combs, Christian Schwager, Amir Abdollahi, Panagiotis Balermpas, Jochen Hess, Anca L. Grosu, Horst Zitzelsberger, Annett Linge, Ute Wirkner, Fabian Lohaus, Melanie Bewerunge-Hudler, Dktk-Rog, Wilko Weichert, P.A. Federspil, Claus Belka, Ute Ganswindt, Katrin Rein, Michael H. Baumann, Philipp Baumeister, Daniel Zips
Publikováno v:
Int. J. Cancer, DOI: 10.1002/ijc.33842 (2021)
Biomarkers with relevance for loco-regional therapy are needed in human papillomavirus negative aka HPV(-) head and neck squamous cell carcinoma (HNSCC). Based on the premise that DNA methylation pattern is highly conserved, we sought to develop a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8abc971113262eef2722448354359d5
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85118946409
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85118946409
Autor:
Peter Weber, Martin Selmansberger, Julia Hess, Herbert Braselmann, Kenji Schorpp, Natasa Anastasov, Ines Höfig, Horst Zitzelsberger, Kristian Unger, A. Michna
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-13 (2020)
Radiation Oncology (London, England)
Radiat. Oncol. 15:182 (2020)
Radiation Oncology (London, England)
Radiat. Oncol. 15:182 (2020)
Background We present a functional gene association network of the CLIP2 gene, generated by de-novo reconstruction from transcriptomic microarray data. CLIP2 was previously identified as a potential marker for radiation induced papillary thyroid carc
Autor:
Kristian Unger, Anne L. Jellema, Nynke A. Hosper, Vivian M.L. Ogundipe, Thera P. Links, Peter W. Nagle, Julia Hess, John T. M. Plukker, Hette Faber, Mirjam Baanstra, Robert P. Coppes, Andries H. Groen
Publikováno v:
Stem Cell Rep. 16, 913-925 (2021)
Stem Cell Reports
Stem Cell Reports, 16(4), 913-925. CELL PRESS
Stem Cell Reports
Stem Cell Reports, 16(4), 913-925. CELL PRESS
Summary Total thyroidectomy as part of thyroid cancer treatment results in hypothyroidism requiring lifelong daily thyroid hormone replacement. Unbalanced hormone levels result in persistent complaints such as fatigue, constipation, and weight increa
Autor:
Juliane Merl-Pham, Claudia A. Staab-Weijnitz, Stefanie M. Hauck, Rudolf Hatz, Julia Hess, Larissa Knüppel, Jürgen Behr, Brendan Lee, Caressa Lietman, Kristian Unger, Ceylan Onursal
Publikováno v:
Idiopathic interstitial pneumonias.
Autor:
Stephan Spahn, Florian Müller, Revant Gupta, Dominik Pfister, Kornelius Schulze, Pierre Bedossa, Eleni Kotsiliti, Lars Zender, Mathias Heikenwalder, Nicolás Gonzalo Núñez, Peter Schirmacher, Axel Schulz, Jan Kosla, Adrian T. Billeter, Thomas Engleitner, Aleksandra Deczkowska, Danijela Heide, Donato Inverso, Susanne Roth, Olivier Govaere, Carla Montironi, Martha M. Kirstein, Dan G. Duda, Antonio D'Alessio, Jörn M. Schattenberg, Ekaterina Friebel, Tiziana Pressiani, F. Hucke, Jörg Trojan, Michael Bitzer, Suhail Yousuf, Bernhard Scheiner, Marina Ruiz de Galarreta, Markus Peck-Radosavljevic, Michael Allison, Nuh N. Rahbari, Simon Cockell, Brinda Emu, Ahmed Kaseb, David J. Pinato, Matthias P. Ebert, Joachim C. Mertens, Jean-François Dufour, Fabian Rössler, Achim Weber, Katharina Wolter, Thomas Decaens, Amaia Lujambio, Anja Moncsek, Daniela Lenggenhager, Katharina Pomej, Nisar P. Malek, Fabian Finkelmeier, Elisabetta Bugianesi, Valentina Leone, Ann K. Daly, Michael Dudek, Manfred Claassen, Zuzana Macek Jilkova, Henning Wege, Florian Castet, Marta Szydlowska, Beat P. Müller-Stich, Ramy Younes, Nicola Personeni, Philipp K. Haber, Marco Bueter, Manfred Jugold, Andrea Schietinger, Hiroto Kikuchi, Ido Amit, Sandra Koch, Dina Tiniakos, Ana Teijeiro, Jan-Philipp Mallm, Josep M. Llovet, Indrabahadur Singh, Percy A. Knolle, Sara De Dosso, Roland Rad, Arndt Vogel, Henrik E. Mei, Burkhard Becher, Nabil Djouder, Tom Luedde, Felix Meissner, Oliver Waidmann, Parice N. Marche, Viktor Umansky, Hellmut G. Augustin, Thomas U. Marron, Matthias Pinter, Mengjie Qiu, Arndt Weinmann, Ankit Sinha, Kristian Unger, Assaf Weiner, Vlad Ratziu, Quentin M. Anstee, Kristin Stirm, Yi Hsiang Huang, Alexander Siebenhüner, Fabian Kütting, Lorenza Rimassa, Dirk Waldschmidt, Masatoshi Kudo, Marc Ringelhan, Michele Vacca, Roser Pinyol, Fabio Marra
Publikováno v:
Nature
Nature, Nature Publishing Group, 2021, 592 (7854), pp.450-456. ⟨10.1038/s41586-021-03362-0⟩
Pfister, Dominik; Núñez, Nicolás Gonzalo; Pinyol, Roser; Govaere, Olivier; Pinter, Matthias; Szydlowska, Marta; Gupta, Revant; Qiu, Mengjie; Deczkowska, Aleksandra; Weiner, Assaf; Müller, Florian; Sinha, Ankit; Friebel, Ekaterina; Engleitner, Thomas; Lenggenhager, Daniela; Moncsek, Anja; Heide, Danijela; Stirm, Kristin; Kosla, Jan; Kotsiliti, Eleni; ... (2021). NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Nature, 592(7854), pp. 450-456. Springer Nature 10.1038/s41586-021-03362-0
Nature, 2021, 592 (7854), pp.450-456. ⟨10.1038/s41586-021-03362-0⟩
Nature, Nature Publishing Group, 2021, 592 (7854), pp.450-456. ⟨10.1038/s41586-021-03362-0⟩
Pfister, Dominik; Núñez, Nicolás Gonzalo; Pinyol, Roser; Govaere, Olivier; Pinter, Matthias; Szydlowska, Marta; Gupta, Revant; Qiu, Mengjie; Deczkowska, Aleksandra; Weiner, Assaf; Müller, Florian; Sinha, Ankit; Friebel, Ekaterina; Engleitner, Thomas; Lenggenhager, Daniela; Moncsek, Anja; Heide, Danijela; Stirm, Kristin; Kosla, Jan; Kotsiliti, Eleni; ... (2021). NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Nature, 592(7854), pp. 450-456. Springer Nature 10.1038/s41586-021-03362-0
Nature, 2021, 592 (7854), pp.450-456. ⟨10.1038/s41586-021-03362-0⟩
Hepatocellular carcinoma (HCC) can have viral or non-viral causes1–5. Non-alcoholic steatohepatitis (NASH) is an important driver of HCC. Immunotherapy has been approved for treating HCC, but biomarker-based stratification of patients for optimal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a22b0e0b30f953f3685c09c1fe9c994
https://www.hal.inserm.fr/inserm-03348110
https://www.hal.inserm.fr/inserm-03348110