Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jiangbin Wu"'
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
Cardiac pathological remodeling, a primary contributor to heart failure (HF) and death, is an important target for HF therapy. However, the signaling pathways that govern cardiac remodeling are not fully elucidated. Here, we found that a functionally
Externí odkaz:
https://doaj.org/article/46b585cfe40c49d98cba3e7b49872458
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1326-1338 (2019)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Alteration of RNA structure by environmental signals is a fundamental mechanism of gene regulation. For example, the riboswitch is a noncoding RNA regulatory element that binds a small molecule and causes a structural change i
Alteration of RNA structure by environmental signals is a fundamental mechanism of gene regulation. For example, the riboswitch is a noncoding RNA regulatory element that binds a small molecule and causes a structural change i
Cardiac fibrosis, a primary contributor to heart failure (HF) and sudden death, is considered as an important target for HF therapy. However, the signaling pathways that govern cardiac fibroblast (CF) function during cardiac fibrosis have not been fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2694f7ba272b8323568555ad91e5563a
https://doi.org/10.1101/2021.02.20.432115
https://doi.org/10.1101/2021.02.20.432115
Autor:
Eric J. Small, Tingting Yang, Amy Mohan, Kevin A. Welle, Omar Hadaya, Chen Yan, Wai Hong Wilson Tang, Feng Jiang, Jiangbin Wu, Kadiam C Venkata Subbaiah, Sina Ghaemmaghami, Peng Yao
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
Aberrant expression of mitochondrial proteins impairs cardiac function and causes heart disease. The mechanism of regulation of mitochondria encoded protein expression during cardiac disease, however, remains underexplored. Here, we show that multipl
Autor:
Deanne Mickelsen, Si Chen, Yi-shuai Zhang, Eric M. Small, Chen Yan, Peng Yao, Jiangbin Wu, Janet K. Lighthouse
Publikováno v:
Circulation
Background: Heart failure is a leading cause of death worldwide. Cyclic nucleotide phosphodiesterases (PDEs), through degradation of cyclic nucleotides, play critical roles in cardiovascular biology and disease. Our preliminary screening studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f65a2d3c30b337a229e387014a90653
https://europepmc.org/articles/PMC7147986/
https://europepmc.org/articles/PMC7147986/
Autor:
Deanne Mickelsen, Feng Jiang, Peng Yao, Kadiam C Venkata Subbaiah, Wai Hong Wilson Tang, Li Huitong Xie, Jason R. Myers, Jiangbin Wu
RationaleIncreased protein synthesis of pro-fibrotic genes is a common feature of cardiac fibrosis, a major manifestation of heart failure. Despite this important observation, critical factors and molecular mechanisms for translational control of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d4c503fa95dd39321dc6c648644ad4
Publikováno v:
Cancer Biology & Therapy
It has been reported that persistent or excessive autophagy promotes cancer cell death during chemotherapy, either by enhancing the induction of apoptosis or mediating autophagic cell death. Here, we show that miR-15a and miR-16 are potent inducers o
Publikováno v:
FEBS Letters. (20):3303-3309
Adipogenic differentiation of preadipocytes is a complex process regulated by various factors including miRNAs and cytokines. MiR-143 is a well known miRNA that enhances adipogenesis. Pleiotrophin (PTN), a heparin-binding growth factor, plays a negat
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 10, Pp 1153-1161 (2024)
The report of the 20th CPC National Congress pointed out that it is necessary to "develop and strengthen the medical and health care workforce, focusing efforts on rural areas and communities". General practitioners (GPs) are the "gatekeepers" of res
Externí odkaz:
https://doaj.org/article/1598afb9eaae4b6aa3bfc66d4828e192