Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Hirokazu Shoji"'
Autor:
Hidekazu Hirano, Yuichi Abe, Yosui Nojima, Masahiko Aoki, Hirokazu Shoji, Junko Isoyama, Kazufumi Honda, Narikazu Boku, Kenji Mizuguchi, Takeshi Tomonaga, Jun Adachi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Phosphoproteomic analysis expands our understanding of cancer biology. However, the feasibility of phosphoproteomic analysis using endoscopically collected tumor samples, especially with regards to dynamic changes upon drug treatment, remain
Externí odkaz:
https://doaj.org/article/23b1b93b6df84053b303f6da1b5e6546
Autor:
Yuri Yoshinami, Hirokazu Shoji
Publikováno v:
Future Science OA, Vol 9, Iss 2 (2023)
Our increasing understanding of the molecular biological characteristics of cancer and of cancer genomics is facilitating the development of immunotherapy and molecular targeted drugs for gastric cancer. After the approval of immune checkpoint inhibi
Externí odkaz:
https://doaj.org/article/be39a33b79494cad9ef527c2fce48545
Autor:
Kotoe Oshima, Hidekazu Hirano, Hirokazu Shoji, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Narikazu Boku
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Background Trifluridine/tipiracil (TFTD), with or without bevacizumab (Bev), and regorafenib are salvage chemotherapy options for metastatic colorectal cancer (mCRC). Here, we examined the influence of precedent drug on the efficacy of subsequent dru
Externí odkaz:
https://doaj.org/article/23096a332ce14b679e99eae3943fe4c7
Publikováno v:
Future Science OA, Vol 7, Iss 7 (2021)
Based on synergistic anti-tumor effects between blockades of NEDD8 activating enzyme and a platinum in preclinical studies, this Phase I study is designed to investigate the safety and tolerability of pevonedistat in combination with capecitabine plu
Externí odkaz:
https://doaj.org/article/329e8191e9354a7daf73d82f0e47e458
Autor:
Masayuki Ohashi, Toru Hirano, Kei Watanabe, Kazuhiro Hasegawa, Takui Ito, Keiichi Katsumi, Hirokazu Shoji, Tatsuki Mizouchi, Ikuko Takahashi, Takao Homma, Naoto Endo
Publikováno v:
Asian Spine Journal, Vol 13, Iss 2, Pp 296-304 (2019)
Study Design Retrospective case series. Purpose To investigate the oncological outcomes, including distant relapse, after en bloc spondylectomy (EBS) for spinal metastases in patients with a minimum of 2-year follow-up. Overview of Literature Althoug
Externí odkaz:
https://doaj.org/article/3be0c50843a74f46a75fc5a62599ae75
Autor:
Masashi Ishikawa, Atsuo Takashima, Yusuke Nagata, Ryoichi Sawada, Masahiko Aoki, Hiroshi Imazeki, Hidekazu Hirano, Hirokazu Shoji, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Ken Kato, Masayuki Saruta, Narikazu Boku
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257551 (2021)
BackgroundIn clinical practice, the same chemotherapeutic agents are occasionally reused (re-challenge) after failure of all available standard chemotherapy options for metastatic colorectal cancer (mCRC). However, the benefits of re-challenge chemot
Externí odkaz:
https://doaj.org/article/80f72f9eb44243b8941b7eac292aa720
Autor:
Hiroyuki Segawa, Kimihiko Sawakami, Tatsuki Mizouchi, Masayuki Ohashi, Hideaki Takahashi, Kazuhiro Hasegawa, Yuki Tanaka, Naoto Endo, Toru Hirano, Seiichi Ishikawa, Kei Watanabe, Noriaki Yamamoto, Hirokazu Shoji, Hiroyuki Kawashima, Taketoshi Shimakura
Publikováno v:
Journal of Neurosurgery: Spine. 36:429-439
OBJECTIVE Teriparatide (TPTD) is a potent promoter of early-stage osteogenesis and may be a useful adjuvant therapy to reduce complications related to bone fragility in spinal surgery patients with osteoporosis. However, effective neoadjuvant TPTD th
Autor:
Haruhiko Fukuda, Akiko Hasegawa, Hitoshi Mizutani, Hirokazu Shoji, Tatsuya Takenouchi, Tetsuya Hamaguchi, Taro Shibata, Naoya Yamazaki, Tomohiro Nishina, Keiko Nozawa, Atsuo Takashima, Toshiki Masuishi, Narikazu Boku, Shusuke Yoshikawa, Akihito Kawazoe, Sumiko Takatsuka, Ryunosuke Machida, Yoshio Kiyohara, Katsuko Kikuchi, Masanobu Takahashi
Publikováno v:
Supportive Care in Cancer. 30:4497-4504
Background: Althoughpre-emptive therapy with oral tetracycline, moisturizer, sunscreen and topical corticosteroid isuseful for preventing acneiform eruption (AfE) due to epidermal growth factor receptor (EGFR) inhibitors, no studies have examinedthe
Autor:
Yoshitaka Honma, Hidekazu Hirano, Satoru Iwasa, Hirokazu Shoji, Ken Kato, Shigemasa Takamizawa, Narikazu Boku, Natsuko Okita, Atsuo Takashima, Shun Yamamoto, Koji Izutsu
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 1, Pp 85-89 (2021)
Case Reports in Oncology
Case Reports in Oncology
Severe thrombocytopenia is a rare adverse event of panitumumab. Here, we report the first patient with metastatic colorectal cancer who developed severe thrombocytopenia, diagnosed as panitumumab-associated drug-induced immune thrombocytopenia (DITP)
Autor:
Keiichi Katsumi, Tatsuki Mizouchi, Toru Hirano, Hirokazu Shoji, Masayuki Ohashi, Kei Watanabe, Kazuhiro Hasegawa, Naoto Endo
Publikováno v:
Journal of Orthopaedic Science. 25:551-556
Background Although several radiographic predictors for pulmonary function in adolescent patients have been reported, those in adult patients remain unclear. Therefore, we aimed to investigate the associations between spinal deformity and pulmonary f