Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Helen Mcdonald"'
Autor:
Andrew Mungall, Richard Moore, Giorgio Bertorelle, Yongjun Zhao, Valeria Angelini, Christopher Kyle, Pawan Pandoh, Sauro Pari, Helen McDonald, Heather Kirk, Dean Cheng, Eric Chuah, Kieran O'Neill, Kane Tse, Jahanshah Ashkani, Luka Culibrk, Samantha Jones, Sreeja Leelakumari, Glenn Chang, Steven Jones, Sibelle Vilaça
Publikováno v:
F1000Research, Vol 12 (2023)
We present a genome assembly of Caretta caretta (the Loggerhead sea turtle; Chordata, Testudines, Cheloniidae), generated from genomic data from two unrelated females. The genome sequence is 2.13 gigabases in size. The assembly has a busco completion
Externí odkaz:
https://doaj.org/article/0969dfd4ef164aeebf43e52b33a603b1
Autor:
The OpenSAFELY Collaborative, Amelia Green, Helen Curtis, William Hulme, Elizabeth Williamson, Helen McDonald, Krishnan Bhaskaran, Christopher Rentsch, Anna Schultze, Brian MacKenna, Viyaasan Mahalingasivam, Laurie Tomlinson, Alex Walker, Louis Fisher, Jon Massey, Colm Andrews, Lisa Hopcroft, Caroline Morton, Richard Croker, Jessica Morley, Amir Mehrkar, Seb Bacon, David Evans, Peter Inglesby, George Hickman, Tom Ward, Simon Davy, Rohini Mathur, John Tazare, Rosalind Eggo, Kevin Wing, Angel Wong, Harriet Forbes, Chris Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian Douglas, Stephen Evans, Liam Smeeth, Ben Goldacre
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background While the vaccines against COVID-19 are highly effective, COVID-19 vaccine breakthrough is possible despite being fully vaccinated. With SARS-CoV-2 variants still circulating, describing the characteristics of individuals who have
Externí odkaz:
https://doaj.org/article/5fb9fd19628a413e9a1d0e9303d74a1c
Autor:
Jennifer Davidson, Amitava Banerjee, Rohini Mathur, Mary Ramsay, Liam Smeeth, Jemma Walker, Helen McDonald, Charlotte Warren-Gash
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: People of non-White ethnicity have a higher risk of severe outcomes following influenza infection. It is unclear whether this is driven by an increased risk of infection or complications. We therefore aimed to investigate the incidence of
Externí odkaz:
https://doaj.org/article/5d19ac7cce7d408a813cec7888f5938d
Autor:
Jennifer Davidson, Amitava Banerjee, Rohini Mathur, Mary Ramsay, Liam Smeeth, Jemma Walker, Helen McDonald, Charlotte Warren-Gash
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: People of non-White ethnicity have a higher risk of severe outcomes following influenza infection. It is unclear whether this is driven by an increased risk of infection or complications. We therefore aimed to investigate the incidence of
Externí odkaz:
https://doaj.org/article/b78233984d9b47e291d14468f9106493
Autor:
Sarah D McDonald, Zhijie Michael Yu, Sherry van Blyderveen, Louis Schmidt, Wendy Sword, Meredith Vanstone, Anne Biringer, Helen McDonald, Joseph Beyene
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233774 (2020)
OBJECTIVE:To develop and validate a prediction model for excess pregnancy weight gain using early pregnancy factors. DESIGN:Prospective cohort study. SETTING:We recruited from 12 obstetrical, family medicine, and midwifery centers in Ontario, Canada.
Externí odkaz:
https://doaj.org/article/a7ab8c84031b479980b2041ef794e491
Autor:
Simon Haile, Richard D Corbett, Steve Bilobram, Karen Mungall, Bruno M Grande, Heather Kirk, Pawan Pandoh, Tina MacLeod, Helen McDonald, Miruna Bala, Robin J Coope, Richard A Moore, Andrew J Mungall, Yongjun Zhao, Ryan D Morin, Steven J Jones, Marco A Marra
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224578 (2019)
Next generation RNA-sequencing (RNA-seq) is a flexible approach that can be applied to a range of applications including global quantification of transcript expression, the characterization of RNA structure such as splicing patterns and profiling of
Externí odkaz:
https://doaj.org/article/9968d3d49a8b44408b7c991245913ad8
Autor:
Simon Haile, Pawan Pandoh, Helen McDonald, Richard D Corbett, Philip Tsao, Heather Kirk, Tina MacLeod, Martin Jones, Steve Bilobram, Denise Brooks, Duane Smailus, Christian Steidl, David W Scott, Miruna Bala, Martin Hirst, Diane Miller, Richard A Moore, Andrew J Mungall, Robin J Coope, Yussanne Ma, Yongjun Zhao, Rob A Holt, Steven J Jones, Marco A Marra
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178706 (2017)
Curation and storage of formalin-fixed, paraffin-embedded (FFPE) samples are standard procedures in hospital pathology laboratories around the world. Many thousands of such samples exist and could be used for next generation sequencing analysis. Retr
Externí odkaz:
https://doaj.org/article/b12c07735fcc4b01b1aaaa704c35b598
Autor:
Daniel Grint, Stephen J. W. Evans, Kevin Wing, John Parry, David M. Evans, Emily Nightingale, Ben Goldacre, John Tazare, Christopher M. Bates, Elizabeth Williamson, Frank Hester, Hamish Gibbs, Christopher T Rentsch, Simon Davy, Alex J Walker, Nicholas J DeVito, Anna Schultze, George Hickman, Amir Mehrkar, Helen Mcdonald, Sam Harper, Ian J. Douglas, Krishnan Bhaskaran, Richard Croker, Rohini Mathur, Catherine F Houlihan, Angel Y S Wong, Liam Smeeth, Caroline E Morton, Laurie A. Tomlinson, William J Hulme, Rosalind M Eggo, Brian MacKenna, Sebastian Bacon, Helen J Curtis, Peter Ingelsby, Jonathan Cockburn
Publikováno v:
Clinical Infectious Diseases. 75:e1120-e1127
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) alpha variant (B.1.1.7) is associated with higher transmissibility than wild-type virus, becoming the dominant variant in England by January 2021. We aimed to describe the se
Autor:
William J Hulme, Rosalind M Eggo, George Hickman, Ian J. Douglas, David M. Evans, Alex Eavis, Ben Goldacre, Angel Y S Wong, Chris Bates, Simon Davy, Laurie A. Tomlinson, John Tazare, Anna Schultze, Elizabeth A. Williamson, Nasreen Parkes, Richard Jarvis, John Parry, Krishnan Bhaskaran, Frank Hester, Helen Mcdonald, Liam Smeeth, Christopher T Rentsch, Rohini Mathur, Alex J Walker, Paul D. Griffiths, Amir Mehrkar, Stephen J. W. Evans, Richard Croker, Helen J Curtis, Caroline E Morton, Peter Inglesby, Jessica Morley, Tom Ward, Jonathan Cockburn, Sam Harper, Aaron Fowles, Kevin Wing, Brian MacKenna, Shaun O'Hanlon, Harriet Forbes, Sebastian Bacon, Dima Avramov
Publikováno v:
The British Journal of General Practice
Br J Gen Pract
Br J Gen Pract
BackgroundLong COVID describes new or persistent symptoms at least 4 weeks after onset of acute COVID-19. Clinical codes to describe this phenomenon were recently created.AimTo describe the use of long-COVID codes, and variation of use by general pra
Autor:
Laurie A. Tomlinson, Chris Bates, Seb Bacon, Elizabeth A. Williamson, Amir Mehrkar, Krishnan Bhaskaran, Henry Drysdale, Richard Croker, Liam Smeeth, Angel Y S Wong, William J Hulme, Rosalind M Eggo, Jonathan Cockburn, Ben Goldacre, Stephen J. W. Evans, Caroline E Morton, Helen J Curtis, Peter Inglesby, Sam Harper, John Parry, Frank Hester, Anna Schultze, Helen Mcdonald, Christopher T Rentsch, Kevin Wing, Alex J Walker, Ian J. Douglas, Harriet Forbes, David M. Evans, Rohini Mathur, Brian MacKenna, Jeremy P Brown
Publikováno v:
Annals of the Rheumatic Diseases
Wong, AY, MacKenna, B, Morton, CE, Schultze, A, Walker, AJ, Bhaskaran, K, Brown, JP, Rentsch, CT, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W & Collaborative, OAFELY 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : an OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Wong, A Y S, MacKenna, B, Morton, C E, Schultze, A, Walker, A J, Bhaskaran, K, Brown, J P, Rentsch, C T, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Evans, D, Inglesby, P, Cockburn, J, McDonald, H I, Tomlinson, L, Mathur, R, Wing, K, Forbes, H, Eggo, R M, Parry, J, Hester, F, Harper, S, Evans, S J W, Smeeth, L, Douglas, I J & Goldacre, B 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : An OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Wong, AY, MacKenna, B, Morton, CE, Schultze, A, Walker, AJ, Bhaskaran, K, Brown, JP, Rentsch, CT, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W & Collaborative, OAFELY 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : an OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Wong, A Y S, MacKenna, B, Morton, C E, Schultze, A, Walker, A J, Bhaskaran, K, Brown, J P, Rentsch, C T, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Evans, D, Inglesby, P, Cockburn, J, McDonald, H I, Tomlinson, L, Mathur, R, Wing, K, Forbes, H, Eggo, R M, Parry, J, Hester, F, Harper, S, Evans, S J W, Smeeth, L, Douglas, I J & Goldacre, B 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : An OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Objectives To assess the association between routinely prescribed non-steroidal anti-inflammatory drugs (NSAIDs) and deaths from COVID-19 using OpenSAFELY, a secure analytical platform.Methods We conducted two cohort studies from 1 March to 14 June 2