Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Basil Sharrack"'
Autor:
Cameron Kirk, Arne Küderle, M. Encarna Micó-Amigo, Tecla Bonci, Anisoara Paraschiv-Ionescu, Martin Ullrich, Abolfazl Soltani, Eran Gazit, Francesca Salis, Lisa Alcock, Kamiar Aminian, Clemens Becker, Stefano Bertuletti, Philip Brown, Ellen Buckley, Alma Cantu, Anne-Elie Carsin, Marco Caruso, Brian Caulfield, Andrea Cereatti, Lorenzo Chiari, Ilaria D’Ascanio, Judith Garcia-Aymerich, Clint Hansen, Jeffrey M. Hausdorff, Hugo Hiden, Emily Hume, Alison Keogh, Felix Kluge, Sarah Koch, Walter Maetzler, Dimitrios Megaritis, Arne Mueller, Martijn Niessen, Luca Palmerini, Lars Schwickert, Kirsty Scott, Basil Sharrack, Henrik Sillén, David Singleton, Beatrix Vereijken, Ioannis Vogiatzis, Alison J. Yarnall, Lynn Rochester, Claudia Mazzà, Bjoern M. Eskofier, Silvia Del Din, Mobilise-D consortium
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-23 (2024)
Abstract This study aimed to validate a wearable device’s walking speed estimation pipeline, considering complexity, speed, and walking bout duration. The goal was to provide recommendations on the use of wearable devices for real-world mobility an
Externí odkaz:
https://doaj.org/article/4d4f15ba723a4186a63dbc95331a29b1
Autor:
Felix Kluge, Yonatan E Brand, M Encarna Micó-Amigo, Stefano Bertuletti, Ilaria D'Ascanio, Eran Gazit, Tecla Bonci, Cameron Kirk, Arne Küderle, Luca Palmerini, Anisoara Paraschiv-Ionescu, Francesca Salis, Abolfazl Soltani, Martin Ullrich, Lisa Alcock, Kamiar Aminian, Clemens Becker, Philip Brown, Joren Buekers, Anne-Elie Carsin, Marco Caruso, Brian Caulfield, Andrea Cereatti, Lorenzo Chiari, Carlos Echevarria, Bjoern Eskofier, Jordi Evers, Judith Garcia-Aymerich, Tilo Hache, Clint Hansen, Jeffrey M Hausdorff, Hugo Hiden, Emily Hume, Alison Keogh, Sarah Koch, Walter Maetzler, Dimitrios Megaritis, Martijn Niessen, Or Perlman, Lars Schwickert, Kirsty Scott, Basil Sharrack, David Singleton, Beatrix Vereijken, Ioannis Vogiatzis, Alison Yarnall, Lynn Rochester, Claudia Mazzà, Silvia Del Din, Arne Mueller
Publikováno v:
JMIR Formative Research, Vol 8, p e50035 (2024)
BackgroundWrist-worn inertial sensors are used in digital health for evaluating mobility in real-world environments. Preceding the estimation of spatiotemporal gait parameters within long-term recordings, gait detection is an important step to identi
Externí odkaz:
https://doaj.org/article/5803ddb3974842249655dbf4f6a0d0ae
Autor:
Gavin Giovannoni, Stephen J Walters, David Paling, Olga Ciccarelli, Cindy Cooper, Eli Silber, Martin Duddy, Hannah Hunter, David Hunt, Basil Sharrack, Paul Gallagher, Ian Galea, Richard Nicholas, Annalena Venneri, Neil Robertson, Carolyn Young, Jeremy Hobart, David Rog, Ben Turner, Muhammad Saif, Azza Ismail, Gavin Brittain, John A Snowden, Diana Papaioannou, Alasdair J Coles, Gordon Mazibrada, Neil Scolding, Maruthi Vinjam, Matthew Bursnall, Claire Rice, Ian Pomeroy, Majid Kazmi, Esmaeil Nikfekr, Kim Orchard, Thushan de Silva, Jennifer Petrie, Elisa Roldan, Caroline Besley, Kate E M Duffy, Rachel Glover, Katie Hullock, Colette Beecher, Ian Gabriel, Charalampia Kyriakou, Andy Peniket, Paolo A Muraro, Amy Publicover, Andy Clark, Charles Crawley, Eleni Tholouli, Fran Kinsella, Gabriele De Luca, Jeff Davies, Jenny Byrne, Keith Campbell, Leonora Finisku, Simon Bulley, Vic Campbell
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Autologous haematopoietic stem cell transplantation (aHSCT) is increasingly used as treatment for patients with active multiple sclerosis (MS), typically after failure of disease-modifying therapies (DMTs). A recent phase III trial, ‘M
Externí odkaz:
https://doaj.org/article/cef35258b9e74bbbaf15d925d8681e1d
Autor:
A. Stefanie Mikolaizak, Lynn Rochester, Walter Maetzler, Basil Sharrack, Heleen Demeyer, Claudia Mazzà, Brian Caulfield, Judith Garcia-Aymerich, Beatrix Vereijken, Valdo Arnera, Ram Miller, Paolo Piraino, Nadir Ammour, Mark Forrest Gordon, Thierry Troosters, Alison J. Yarnall, Lisa Alcock, Heiko Gaßner, Jürgen Winkler, Jochen Klucken, Christian Schlenstedt, Henrik Watz, Anne-Marie Kirsten, Ioannis Vogiatzis, Nikolaos Chynkiamis, Emily Hume, Dimitrios Megaritis, Alice Nieuwboer, Pieter Ginis, Ellen Buckley, Gavin Brittain, Giancarlo Comi, Letizia Leocani, Jorunn L. Helbostad, Lars Gunnar Johnsen, Kristin Taraldsen, Hubert Blain, Valérie Driss, Anja Frei, Milo A. Puhan, Ashley Polhemus, Magda Bosch de Basea, Elena Gimeno, Nicholas S. Hopkinson, Sara C. Buttery, Jeffrey M. Hausdorff, Anat Mirelman, Jordi Evers, Isabel Neatrour, David Singleton, Lars Schwickert, Clemens Becker, Carl-Philipp Jansen
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Background The development of optimal strategies to treat impaired mobility related to ageing and chronic disease requires better ways to detect and measure it. Digital health technology, including body worn sensors, has the potential to directly and
Externí odkaz:
https://doaj.org/article/21df0d08eef542bf8d7ef9b59450a4a7
Autor:
Sarah Koch, Clint Hansen, Walter Maetzler, Anne-Elie Carsin, Kristin Taraldsen, Kamiar Aminian, Clemens Becker, Lorenzo Chiari, Anisoara Paraschiv-Ionescu, Jorunn L Helbostad, Beatrix Vereijken, Lynn Rochester, Philip Brown, Judith Garcia Aymerich, David Singleton, Basil Sharrack, Brian Caulfield, Ellen Buckley, Claudia Mazza, Nikolaos Chynkiamis, Felix Kluge, M Encarna Micó-Amigo, Francesca Salis, Lars Schwickert, Kirsty Scott, Ioannis Vogiatzis, Alison Yarnall, Alison Keogh, Silvia Del Din, Björn Eskofier, Lisa Alcock, Stefano Bertuletti, Tecla Bonci, Marina Brozgol, Marco Caruso, Andrea Cereatti, Fabio Ciravegna, Jordi Evers, Eran Gazit, Jeffrey M Hausdorff, Hugo Hiden, Emily Hume, Neil Ireson, Cameron Kirk, Arne Küderle, Vitaveska Lanfranchi, Arne Mueller, Isabel Neatrour, Martijn Niessen, Luca Palmerini, Lucas Pluimgraaff, Luca Reggi, Henrik Sillen, Abolfazi Soltani, Martin Ullrich, Linda Van Gelder, Elke Warmerdam
Publikováno v:
BMJ Open, Vol 11, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/cbec236cfd144ae6ad602b429d118e47
Autor:
Sarah Koch, Clint Hansen, Milo Alan Puhan, Walter Maetzler, Anja Frei, Kristin Taraldsen, A Stefanie Mikolaizak, Clemens Becker, Ronny Bergquist, Beatrix Vereijken, Lynn Rochester, Judith Garcia Aymerich, Basil Sharrack, Ashley Marie Polhemus, Magda Bosch de Basea, Gavin Brittain, Sara Catherine Buttery, Nikolaos Chynkiamis, Gloria dalla Costa, Laura Delgado Ortiz, Heleen Demeyer, Kirsten Emmert, Heiko Gassner, Nicholas Hopkinson, Jochen Klucken, Felix Kluge, Letizia Leocani, M Encarna Micó-Amigo, Paolo Piraino, Francesca Salis, Christian Schlenstedt, Lars Schwickert, Kirsty Scott, Thierry Troosters, Ioannis Vogiatzis, Alison Yarnall
Publikováno v:
BMJ Open, Vol 10, Iss 7 (2020)
Introduction Advances in wearable sensor technology now enable frequent, objective monitoring of real-world walking. Walking-related digital mobility outcomes (DMOs), such as real-world walking speed, have the potential to be more sensitive to mobili
Externí odkaz:
https://doaj.org/article/7587f202ed18452698f3a623dffbd7fe
Autor:
Floriana De Angelis, Peter Connick, Richard A Parker, Domenico Plantone, Anisha Doshi, Nevin John, Jonathan Stutters, David MacManus, Ferran Prados, Ian Marshall, Bhavana Solanky, Rebecca S Samson, Frederik Barkhof, Sebastien Ourselin, Marie Braisher, Moira Ross, Gina Cranswick, Sue H Pavitt, Sharmilee Gnanapavan, Gavin Giovannoni, Claudia AM Gandini Wheeler-Kingshott, Clive Hawkins, Basil Sharrack, Roger Bastow, Christopher J Weir, Nigel Stallard, Siddharthan Chandran, Jeremy Chataway
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 7, Iss 3 (2020)
Background: Neuroprotective drugs are needed to slow or prevent neurodegeneration and disability accrual in secondary progressive multiple sclerosis. Amiloride, fluoxetine and riluzole are repurposed drugs with potential neuroprotective effects. Obje
Externí odkaz:
https://doaj.org/article/1bf07b99cbbe44a4b0f26520d86e3ec8
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0236611 (2020)
Treatment of diseases that affect the CNS by gene therapy requires delivery of oligonucleotides to target cells within the brain. As the blood brain barrier prevents movement of large biomolecules, current approaches involve direct injection of the o
Externí odkaz:
https://doaj.org/article/06e127e6e81d4696976d82b45c687bfb
Autor:
Nidaa A Ababneh, Dema Ali, Ban Al-Kurdi, Malik Sallam, Abdulla M Alzibdeh, Bareqa Salah, Abdee T Ryalat, Belal Azab, Basil Sharrack, Abdalla Awidi
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0236808 (2020)
BackgroundAtaxia with oculomotor apraxia type 1 (AOA1) is a rare autosomal recessive cerebellar ataxia, caused by mutations in the APTX gene. The disease is characterized by early-onset cerebellar ataxia, oculomotor apraxia and severe axonal polyneur
Externí odkaz:
https://doaj.org/article/e00440be39a14557918654be88567cf5
Autor:
Radka Gromnicova, Mehmet Kaya, Ignacio A Romero, Phil Williams, Simon Satchell, Basil Sharrack, David Male
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161610 (2016)
The selective entry of nanoparticles into target tissues is the key factor which determines their tissue distribution. Entry is primarily controlled by microvascular endothelial cells, which have tissue-specific properties. This study investigated th
Externí odkaz:
https://doaj.org/article/aec69b3e8bcf468cad4945e92fd12dbf