Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Aruna Chakrabarty"'
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 74:2776-2820
Common peroneal nerve (CPN) injury is a recognised complication of traumatic knee dislocation with a direct association between the degree of ligamentous injury and the degree of CPN injury. It is essential explore and repair these injuries in good t
Autor:
Martin Sill, Jessica C Pickles, Abigail F Peary, Mark Kristiansen, David T.W. Jones, Steven C. Clifford, Dariusz Ladon, David A Hilton, Darren Hargrave, SA Yasin, David Capper, Nitika Rathi, Aimee Avery, Olumide Ogunbiyi, Amy R Fairchild, Marie Edwards, Lawrence Doey, Kathreena M Kurian, G. Alistair Lammie, Chris Jones, Antonia Torgersen, Ashirwad Merve, Lorelle Brownlee, Rebecca M Hill, James A. R. Nicoll, Yura Grabovska, Azzam Ismail, Frances Rae, Thomas S. Jacques, Daniel Williamson, Aruna Chakrabarty, Clara Limback-Stanic, Tabitha Bloom, Safa Al-Sarraj, Jamie Gonzalez Zapata, Catherine Rowe, Leslie R. Bridges, Stefan M. Pfister, Carryl Dryden, Saira W. Ahmed, Khaja Syed, Lisa Wilkhu, Colin Smith, Thomas J Stone, Paul N Johns, Andreas von Deimling, Matthew Clarke, Clare Mitchell, Jane Chalker
Publikováno v:
Pickles, J C, Fairchild, A R, Stone, T J, Brownlee, L, Merve, A, Yasin, S A, Avery, A, Ahmed, S W, Ogunbiyi, O, Gonzalez Zapata, J, Peary, A F, Edwards, M, Wilkhu, L, Dryden, C, Ladon, D, Kristiansen, M, Rowe, C, Kurian, K M, Nicoll, J A R, Mitchell, C, Bloom, T, Hilton, D A, Al-Sarraj, S, Doey, L, Johns, P N, Bridges, L R, Chakrabarty, A, Ismail, A, Rathi, N, Syed, K, Lammie, G A, Limback-Stanic, C, Smith, C, Torgersen, A, Rae, F, Hill, R M, Clifford, S C, Grabovska, Y, Williamson, D, Clarke, M, Jones, C, Capper, D, Sill, M, von Deimling, A, Pfister, S M, Jones, D T W, Hargrave, D, Chalker, J & Jacques, T S 2020, ' DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment : a population-based study ', The Lancet Child and Adolescent Health, vol. 4, no. 2, pp. 121-130 . https://doi.org/10.1016/S2352-4642(19)30342-6
Summary Background Marked variation exists in the use of genomic data in tumour diagnosis, and optimal integration with conventional diagnostic technology remains uncertain despite several studies reporting improved diagnostic accuracy, selection for
Autor:
Lucy F. Stead, Daniel J. Brat, Michael D. Jenkinson, Michael Schuster, Michael Weller, Hiromichi Suzuki, Raul Rabadan, Kristin Alfaro, Do-Hyun Nam, D. Ryan Ormond, Gaetano Finocchiaro, Anzhela D. Moskalik, Hoon Kim, Jason K. Sa, Mustafa Khasraw, Chew Yee Ngan, Andrew E. Sloan, Peter Gould, Mark R. Gilbert, Ganesh Rao, Michael N. C. Fletcher, Brian L. Shaw, Houtan Noushmehr, Ketan R. Bulsara, Naema Nayyar, Elizabeth B. Claus, Colin Watts, Samirkumar B. Amin, Pim J. French, Rameen Beroukhim, Azzam Ismail, Erwin G. Van Meir, Matthew R. Grimmer, Andrew R Brodbelt, Joseph F. Costello, W. K. Alfred Yung, Susan C Short, Meihong Li, Guido Reifenberger, Adelheid Woehrer, Aruna Chakrabarty, Hui K Gan, Keith L. Ligon, Roel G.W. Verhaak, Chul-Kee Park, Simone P. Niclou, Georgette Tanner, Frederick S. Varn, Arnab Chakravarti, Javad Noorbakhsh, Floris P. Barthel, Jason T. Huse, Christoph Bock, Annette M. Molinaro, Georg Widhalm, Alexander F. Bruns, Olajide Abiola, Tathiane M. Malta, Pieter Wesseling, Tali Mazor, Donát Alpár, Peter Lichter, Jill S. Barnholtz-Sloan, Priscilla K. Brastianos, Antonio Iavarone, Laila M. Poisson, Jennifer Connelly, Bernhard Radlwimmer, Gelareh Zadeh, David M. Ashley, Ho Keung Ng, Ghazaleh Tabatabai, Peter A. E. Sillevis Smitt, Mathilde C.M. Kouwenhoven, Elizabeth J. Cochran, Jeffrey H. Chuang, Pratiti Bandopadhayay, Kevin C. Johnson, Marion Smits, Allison Lowman, John de Groot, Kevin J. Anderson, Johanna M. Niers, Bart A. Westerman, Peter S. LaViolette, Emre Kocakavuk, Kenneth Aldape, Kerrie L. McDonald
Publikováno v:
Nature, vol 576, iss 7785
Nature, 576(7785), 112-120. Nature Publishing Group
Nature
Barthel, F P, Johnson, K C, Varn, F S, Moskalik, A D, Tanner, G, Kocakavuk, E, Anderson, K J, Abiola, O, Aldape, K, Alfaro, K D, Alpar, D, Amin, S B, Ashley, D M, Bandopadhayay, P, Barnholtz-Sloan, J S, Beroukhim, R, Bock, C, Brastianos, P K, Brat, D J, Brodbelt, A R, Bruns, A F, Bulsara, K R, Chakrabarty, A, Chakravarti, A, Chuang, J H, Claus, E B, Cochran, E J, Connelly, J, Costello, J F, Finocchiaro, G, Fletcher, M N, French, P J, Gan, H K, Gilbert, M R, Gould, P V, Grimmer, M R, Iavarone, A, Ismail, A, Jenkinson, M D, Khasraw, M, Kim, H, Kouwenhoven, M C M, LaViolette, P S, Li, M, Lichter, P, Ligon, K L, Lowman, A K, Malta, T M, Mazor, T, McDonald, K L, Molinaro, A M, Nam, D H, Nayyar, N, Ng, H K, Ngan, C Y, Niclou, S P, Niers, J M, Noushmehr, H, Noorbakhsh, J, Ormond, D R, Park, C K, Poisson, L M, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, J K, Schuster, M, Shaw, B L, Short, S C, Smitt, P A S, Sloan, A E, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, E G, Watts, C, Weller, M, Wesseling, P, Westerman, B A, Widhalm, G, Woehrer, A, Yung, W K A, Zadeh, G, Huse, J T, De Groot, J F, Stead, L F, Verhaak, R G W & The GLASS Consortium 2019, ' Longitudinal molecular trajectories of diffuse glioma in adults ', Nature, vol. 576, no. 7785, pp. 112-120 . https://doi.org/10.1038/s41586-019-1775-1, https://doi.org/10.1038/s41586-019-1775-1
Nature, 576(7785), 112-120. Nature Publishing Group
Nature
Barthel, F P, Johnson, K C, Varn, F S, Moskalik, A D, Tanner, G, Kocakavuk, E, Anderson, K J, Abiola, O, Aldape, K, Alfaro, K D, Alpar, D, Amin, S B, Ashley, D M, Bandopadhayay, P, Barnholtz-Sloan, J S, Beroukhim, R, Bock, C, Brastianos, P K, Brat, D J, Brodbelt, A R, Bruns, A F, Bulsara, K R, Chakrabarty, A, Chakravarti, A, Chuang, J H, Claus, E B, Cochran, E J, Connelly, J, Costello, J F, Finocchiaro, G, Fletcher, M N, French, P J, Gan, H K, Gilbert, M R, Gould, P V, Grimmer, M R, Iavarone, A, Ismail, A, Jenkinson, M D, Khasraw, M, Kim, H, Kouwenhoven, M C M, LaViolette, P S, Li, M, Lichter, P, Ligon, K L, Lowman, A K, Malta, T M, Mazor, T, McDonald, K L, Molinaro, A M, Nam, D H, Nayyar, N, Ng, H K, Ngan, C Y, Niclou, S P, Niers, J M, Noushmehr, H, Noorbakhsh, J, Ormond, D R, Park, C K, Poisson, L M, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, J K, Schuster, M, Shaw, B L, Short, S C, Smitt, P A S, Sloan, A E, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, E G, Watts, C, Weller, M, Wesseling, P, Westerman, B A, Widhalm, G, Woehrer, A, Yung, W K A, Zadeh, G, Huse, J T, De Groot, J F, Stead, L F, Verhaak, R G W & The GLASS Consortium 2019, ' Longitudinal molecular trajectories of diffuse glioma in adults ', Nature, vol. 576, no. 7785, pp. 112-120 . https://doi.org/10.1038/s41586-019-1775-1, https://doi.org/10.1038/s41586-019-1775-1
The evolutionary processes that drive universal therapeutic resistance in adult patients with diffuse glioma remain unclear1,2. Here we analysed temporally separated DNA-sequencing data and matched clinical annotation from 222 adult patients with gli
Autor:
Jochen Walter, Aruna Chakrabarty, Christine A. F. von Arnim, Adrian Smith, Kerstin Heurling, Thomas G. Beach, Azzam Ismail, Mathieu Vandenbulcke, Ajeet Rijal Upadhaya, Johan Lilja, Karthikeyan Balakrishnan, Gill Farrar, Rik Vandenberghe, Sathish Kumar, Alicja Ronisz, Thomas Tousseyn, Christopher Buckley, Markus Otto, Dietmar Rudolf Thal
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and undergoes qualitative changes in its comp
Autor:
Gill Farrar, Michelle Zanette, Adrian Smith, Kerstin Heurling, Johan Lilja, Dietmar Rudolf Thal, Aruna Chakrabarty, Thomas G. Beach, Azzam Ismail, Christopher Buckley
Publikováno v:
Acta Neuropathologica
The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological hallmarks of Alzheimer’s disease (AD). Aβ-plaques arise first in neocortical areas and, then, expand into further brain regions in a process described
Autor:
Aruna Chakrabarty, Alastair Droop, Azzam Ismail, Muna Al-Jabri, Matthew A. Care, Susan C Short, Lucy F. Stead, Michael D. Jenkinson, Alexander-F Bruns, Nora Rippaus, Andrew Brodbelt
Publikováno v:
Neuro Oncol
Recent findings from our group, and the wider community, show that standard treatment does not impose an apparent bottleneck on the clonal evolution of adult glioblastoma (GBM), implying a lack of direct therapeutic opportunity. This does not negate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd77c1a9650952b43188ddbd7bb8ac7e
https://eprints.whiterose.ac.uk/162285/1/Bruns.docx
https://eprints.whiterose.ac.uk/162285/1/Bruns.docx
Autor:
Lucy F. Stead, Michael D. Jenkinson, Georgette Tanner, Katherine M. Ashton, Andrew Brodbelt, Susan C Short, Azzam Ismail, Sally M. Harrison, Khaja Syed, Ruth Morton, Nora Rippaus, Aruna Chakrabarty, Henry King, Alastair Droop, Alexander F. Bruns
Publikováno v:
International Journal of Cancer. 142:1620-1626
Many traits of cancer progression (e.g., development of metastases or resistance to therapy) are facilitated by tumour evolution: Darwinian selection of subclones with distinct genotypes or phenotypes that enable such progression. Characterising thes
Autor:
Lucy F. Stead, Michael D. Jenkinson, J Manning, Susan C Short, Andrew Brodbelt, Matthew A. Care, Aruna Chakrabarty, M Al-Jabri, Alexander-Francisco Bruns, Alastair Droop, Azzam Ismail, Nora Rippaus
Publikováno v:
Neuro Oncol
BACKGROUND Glioblastoma (GBM) tumours recur following standard treatment in almost all cases. We use ‘omics technologies to simultaneously profile pairs of primary and matched recurrent GBM to specifically identify and characterise the cells that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ea6825e971b705d08bb8a537479c20
https://eprints.whiterose.ac.uk/162286/1/Rippaus_EANO2019abstract.docx
https://eprints.whiterose.ac.uk/162286/1/Rippaus_EANO2019abstract.docx
Publikováno v:
Rheumatology. 58
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
Background Intracranial and intraspinal tumours are the most numerous solid tumours in children. Some recently defined subtypes are relatively frequent in childhood. Many cancer registries routinely ascertain CNS tumours of all behaviours, while othe