Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anssi Lipponen"'
Autor:
Anssi Lipponen, Aleksi Kolehmainen, Sami Oikarinen, Anna-Maria Hokajärvi, Kirsi-Maarit Lehto, Annamari Heikinheimo, Jani Halkilahti, Aapo Juutinen, Oskari Luomala, Teemu Smura, Kirsi Liitsola, Soile Blomqvist, Carita Savolainen-Kopra, Tarja Pitkänen, WastPan Study Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants may have different characteristics, e.g., in transmission, mortality, and the effectiveness of vaccines, indicating the importance of variant detection at the population l
Externí odkaz:
https://doaj.org/article/6281527677244848b45fb2bda219b9a4
Autor:
Noora Puhakka, Asla Pitkänen, Johanna Hiltunen, Anssi Lipponen, Günther Sperk, Xavier Ekolle Ndode-Ekane, Meinrad Drexel
Publikováno v:
Neuroscience. 475:52-72
Traumatic brain injury (TBI) causes 10–20% of structural epilepsy, with seizures typically originating in the cortex. Alterations in the neuronal microcircuits in the cortical epileptogenic zone, however, are poorly understood. Here, we assessed TB
Autor:
Xavier Ekolle Ndode-Ekane, Heikki Tanila, Anssi Lipponen, Laura Oliva Pérez, Jenni Kyyriäinen, Asla Pitkänen, Hennariikka Koivisto, Tamuna Bolkvadze
Publikováno v:
Epilepsy Research. 151:67-74
Extracellular proteolysis initiated by the binding of urokinase-type plasminogen activator (uPA) to its receptor (uPAR) regulates the development of inhibitory neuronal circuits in the cerebral cortex and tissue remodeling after epileptogenic brain i
Publikováno v:
Neuroscience Letters. 729:134935
Binding of urokinase-type plasminogen activator receptor (uPAR) to its ligand uPA or to its plasma membrane partner, platelet-derived growth factor receptor β (PDGFRβ), promotes neuroprotection, cell proliferation, and angiogenesis. Following injur
Publikováno v:
Scientific Reports
We aimed to define the chronically altered gene expression signature of traumatic brain injury (TBI-sig) to discover novel treatments to reverse pathologic gene expression or reinforce the expression of recovery-related genes. Genome-wide RNA-sequenc
Autor:
Jenni Kyyriäinen, Anssi Lipponen, Anu Lipsanen, Xavier Ekolle Ndode-Ekane, Tamuna Bolkvadze, Alejandra Sierra, Noora Huusko, Asla Pitkänen
Publikováno v:
Neurobiology of Disease, Vol 72, Iss, Pp 224-232 (2014)
Disease modification of epilepsy refers to the alleviation of epileptogenesis or comorbidities after genetic or acquired epileptogenic brain insults. There are currently 30 proof-of-concept experimental pharmacologic studies that have demonstrated so