Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andrei Loas"'
Autor:
Chia-Ling Wu, Annika B. Malmberg, Jenna A. Wood, Andrei Loas, Kamela Bellovoda, Eva M. López-Vidal, Carly K. Schissel, Somesh Mohapatra, Bradley L. Pentelute, Rafael Gómez-Bombarelli
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 2009-2020 (2021)
JACS Au
JACS Au
Therapeutic macromolecules such as proteins and oligonucleotides can be highly efficacious but are often limited to extracellular targets due to the cell's impermeable membrane. Cell-penetrating peptides (CPPs) are able to deliver such macromolecules
Autor:
Genwei Zhang, Chengxi Li, Hong Zong, Nina Hartrampf, David Verhoeven, Carly K. Schissel, Gunnar J. Hanson, Alexander J. Mijalis, Bradley L. Pentelute, Kyle A. Totaro, Nicola L. B. Pohl, Kruttika-Suhas Phadke, Mark D. Simon, Andrei Loas, Ming Zhou, Alex J. Callahan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature Communications
Rapid development of antisense therapies can enable on-demand responses to new viral pathogens and make personalized medicine for genetic diseases practical. Antisense phosphorodiamidate morpholino oligomers (PMOs) are promising candidates to fill su
Autor:
Yen-Chun Lee, Gilles Berger, Mykola Zdioruk, Michał Nowicki, Tomer Finkelberg, Andrei Loas, Choi-Fong Cho, Jorge Jimenez Macias, Bogdan Fedeles, Bradley L. Pentelute, Sean E. Lawler
Publikováno v:
Neuro Oncol
INTRODUCTION Glioblastoma (GBM), an aggressive brain tumor with a poor prognosis, presents an average of 2% of patients surviving beyond 2 years after diagnosis. Therapies to effectively manage glioblastoma are hindered due to the presence of the blo
Autor:
Daniel Garafola, R. John Collier, Bradley L. Pentelute, Hidde L. Ploegh, Carly K. Schissel, Alexander R. Loftis, Andrei Loas, Genwei Zhang, Anthony J. Quartararo, Coralie Backlund, Novalia Pishesha, Darrell J. Irvine
Targeting of antigens to erythrocytes can be used to selectively mitigate their immunogenicity, but the methods to equip a variety of cargoes with erythrocyte-targeting properties are limited. Here we identified a D-peptide that targets murine erythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a507e94dc21a6673c687703ad1c1b3cc
https://doi.org/10.1101/2020.07.15.203331
https://doi.org/10.1101/2020.07.15.203331
Autor:
Rafael Gómez-Bombarelli, Andrei Loas, Somesh Mohapatra, Chia-Ling Wu, Colin M. Fadzen, Carly K. Schissel, Annika B. Malmberg, Justin M. Wolfe, Kamela Bellovoda, Bradley L. Pentelute, Jenna A. Wood
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space hinders the use of human learning to design functional polymers. Here we couple supervised and unsupervised deep learning with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c093b86f73cfa35cae5d339b2727c067
https://doi.org/10.1101/2020.04.10.036566
https://doi.org/10.1101/2020.04.10.036566
Autor:
Andrei Loas, Alexander R. Loftis, Sebastian Pomplun, Genwei Zhang, Bradley L. Pentelute, Xuyu Tan
Coronavirus disease 19 (COVID-19) is an emerging global health crisis. With over 7 million confirmed cases to date, this pandemic continues to expand, spurring research to discover vaccines and therapies. SARS-CoV-2 is the novel coronavirus responsib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b86fdb51d806b1994d9dba92381a5c1d
https://doi.org/10.1101/2020.03.19.999318
https://doi.org/10.1101/2020.03.19.999318