Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Alan Altraja"'
Autor:
Susanne Hansen, Anna von Bülow, Patrik Sandin, Olivia Ernstsson, Christer Janson, Lauri Lehtimäki, Hannu Kankaanranta, Charlotte Ulrik, Bernt Bøgvald Aarli, Hanna Fues Wahl, Kirk Geale, Sheila Tuyet Tang, Maija Wolf, Tom Larsen, Alan Altraja, Helena Backman, Maritta Kilpeläinen, Arja Viinanen, Dora Ludviksdottir, Paula Kauppi, Asger Sverrild, Sverre Lehmann, Vibeke Backer, Valentyna Yasinska, Tina Skjold, Jussi Karjalainen, Apostolos Bossios, Celeste Porsbjerg
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Real-life evidence on prevalence and management of severe asthma is limited. Nationwide population registries across the Nordic countries provide unique opportunities to describe prevalence and management patterns of severe asthma at popul
Externí odkaz:
https://doaj.org/article/53bc481cf3ba47f2b816ed9063f899ad
Autor:
Ott Kiens, Egon Taalberg, Viktoria Ivanova, Ketlin Veeväli, Triin Laurits, Ragne Tamm, Aigar Ottas, Kalle Kilk, Ursel Soomets, Alan Altraja
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Background The apnoea–hypopnoea index (AHI) forms the basis for severity of obstructive sleep apnoea (OSA), a condition expected to reprogramme metabolic pathways in humans. We aimed to identify the AHI breakpoint from which the majority of signifi
Externí odkaz:
https://doaj.org/article/e7481e4c4d0849418390c126aa46a092
Autor:
Ott Kiens, Egon Taalberg, Viktoria Ivanova, Ketlin Veeväli, Triin Laurits, Ragne Tamm, Aigar Ottas, Kalle Kilk, Ursel Soomets, Alan Altraja
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract There are no clinical studies that have investigated the differences in blood serum metabolome between obstructive sleep apnea (OSA) patients and controls. In a single-center prospective observational study, we compared metabolomic profiles
Externí odkaz:
https://doaj.org/article/9ab2f606810e46d7a27d8978cc1a1e17
Autor:
Dzmitriy Zhurkin, Elmira Gurbanova, Jonathon R. Campbell, Dick Menzies, Svetlana Setkina, Hennadz Hurevich, Varvara Solodovnikova, Dzmitry Viatushka, Alan Altraja, Alena Skrahina
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Bedaquiline is now considered a first-line medicine for treatment of rifampicin-resistant tuberculosis (RR-TB). We evaluated the safety of treatment with bedaquiline for longer than 190 days in individuals with RR-TB under programmatic conditions. In
Externí odkaz:
https://doaj.org/article/f96b8d3f622d45fd9570bfeec4316a7f
Autor:
Miriam Barrecheguren, Karen O'Hara, Marion Wilkens, Jeanette Boyd, Ewa Kolda, Beatriz Lara, Joanna Chorostowska-Wynimko, Ilaria Ferrarotti, Jan Chlumský, Christian Clarenbach, Timm Greulich, Marc Miravitlles, Maria Sucena, Members of EARCO CRC Timm Greulich (Germany, co-chair) Marc Miravitlles (Spain co-chair). Steering committee:, Joanna Chorostowska-Wymiko (Poland), Ilaria Ferrarotti (Italy), Noel G. McElvaney (Ireland), Karen O'Hara (UKpatients' representative), Jan Stolk (Netherlands), Robert A. Stockley, Alice Turner (UK), Marion Wilkens (Germany patients' representative), EARCO members:, Angelo Corsico, Luciano Corda (Italy), Maria Sucena (Portugal), Miriam Barrecheguren (Spain ERS early career representative), Cristina Esquinas (Spain), David Parr, Ravi Mahadeva (UK), Jan Chlumsky (Czech Republic), Sabina Janciauskiene, Robert Bals (Germany), Jens Ulrik Jensen (Denmark), Kostas Kostikas (Greece), Malcolm Kohler, Christian Clarenbach (Switzerland), Alan Altraja (Estonia), Wim Jenssens, Silvia Pérez-Bogerd (Belgium), Caroline Gouder (Malta), Ana Hecimovic (Croatia), Aleksandra Dudvarski (Serbia), Alvils Krams (Latvia), Ruxandra Ulmeanu, Ana Zaharie (Rumania), Jean-François Mornex (France), Arzu Yorgancioglu (Tukey), Karin Schmid-Scherzer (Austria), Hanan Tanash, Eeva Piitulainen (Sweden), Oleksandr Mazulov (Ukraine), Yavor Ivanov (Bulgaria)
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
α1-antitrypsin deficiency (AATD) is a rare and under-recognised genetic condition. Owing to its low prevalence, international initiatives are key for conducting high-quality research in the field. From July 2018 to December 2019, the European Alpha-
Externí odkaz:
https://doaj.org/article/3dc0881f12aa43ff84cc6643d3544e50
Autor:
Timm Greulich, Alan Altraja, Miriam Barrecheguren, Robert Bals, Jan Chlumsky, Joanna Chorostowska-Wynimko, Christian Clarenbach, Luciano Corda, Angelo Guido Corsico, Ilaria Ferrarotti, Cristina Esquinas, Caroline Gouder, Ana Hećimović, Aleksandra Ilic, Yavor Ivanov, Sabina Janciauskiene, Wim Janssens, Malcolm Kohler, Alvils Krams, Beatriz Lara, Ravi Mahadeva, Gerry McElvaney, Jean-François Mornex, Karen O'Hara, David Parr, Eava Piitulainen, Karin Schmid-Scherzer, Niels Seersholm, Robert A. Stockley, Jan Stolk, Maria Sucena, Hanan Tanash, Alice Turner, Ruxandra Ulmeanu, Marion Wilkens, Arzu Yorgancioğlu, Ana Zaharie, Marc Miravitlles
Publikováno v:
ERJ Open Research, Vol 6, Iss 1 (2020)
Rationale and objectives Alpha-1 antitrypsin deficiency (AATD) is a genetic condition that leads to an increased risk of emphysema and liver disease. Despite extensive investigation, there remain unanswered questions concerning the natural history, p
Externí odkaz:
https://doaj.org/article/19427942e70f4ec99e35aebb5bcf081f
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142053 (2015)
E-cigarettes are widely believed to be safer than conventional cigarettes and have been even suggested as aids for smoking cessation. However, while reasonable with some regards, this judgment is not yet supported by adequate biomedical research data
Externí odkaz:
https://doaj.org/article/15195fe6ed35496594106bff572e28ce
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70333 (2013)
Chronic oxidative stress (OS), a major mechanism of chronic obstructive pulmonary disease (COPD), may cause significant damage to DNA. Poly(ADP-ribose) polymerase (PARP)-1 is rapidly activated by OS-induced DNA lesions. However, the degree of DNA dam
Externí odkaz:
https://doaj.org/article/37ffee5efbad4ec7b1fc5e0227de7332
Autor:
James Zangrilli, Liam G Heaney, Paul E Pfeffer, John Busby, Vibeke Backer, Takashi Iwanaga, Isha Chaudhry, Marjan Kerkhof, Celeste Porsbjerg, Enrico Heffler, Trung N. Tran, Mark Hew, Lakmini Bulathsinhala, Guy Brusselle, Marianna Alacqua, Todor A. Popov, Sverre Lehmann, Nikolaos G. Papadopoulos, Lauri Lehtimäki, Chris A. Price, Victoria Carter, Roland Buhl, Matthew J. Peters, Leif Bjermer, Alan Altraja, David A. Jackson, Yuji Tohda, Luis Pérez de Llano, Arnaud Bourdin, Chin Kook Rhee, Christian Taube, J. Mark FitzGerald, Mariko Siyue Koh, Unnur S. Bjornsdottir, Neva Eleangovan, Giorgio Walter Canonica, Andriana I. Papaioannou, David Price, Naeimeh Hosseini, Camille Taillé, Borja G. Cosío, Michael E. Wechsler, Mona Al-Ahmad, Mohsen Sadatsafavi, Andrew Menzies-Gow, Ruth Murray, George Christoff, Richard W. Costello, Eileen Wang
Publikováno v:
Chest. 160:814-830
Background Phenotypic characteristics of patients with eosinophilic and noneosinophilic asthma are not well characterized in global, real-life severe asthma cohorts. Research Question What is the prevalence of eosinophilic and noneosinophilic phenoty
Autor:
Guy Brusselle, Victoria Carter, Liam G Heaney, Matthew J. Peters, Takashi Iwanaga, Luis Pérez de Llano, Isha Chaudhry, Celeste Porsbjerg, Lakmini Bulathsinhala, Marianna Alacqua, J. Mark FitzGerald, Anke-Hilse Maitland-van der Zee, Vicente Plaza, Yuji Tohda, Nikolaos G. Papadopoulos, Vibeke Backer, Ruth Murray, Mariko Koh Siyue, George Christoff, Neva Eleangovan, You Sook Cho, Arnaud Bourdin, Mohsen Sadatsafavi, Andrew Menzies-Gow, G. Walter Canonica, Sverre Lehmann, Chin Kook Rhee, James Zangrilli, Richard W. Costello, Rupert Jones, Leif Bjermer, Naeimeh Hosseini, Thao Le, Dora Ludviksdottir, David Price, Mark Hew, Peter G. Gibson, Elisabeth H. Bel, Enrico Heffler, Alan Altraja, Trung N. Tran, Borja G. Cosío, Lauri Lehtimäki, Chris A. Price, Unnur S. Bjornsdottir, Eileen Wang
Publikováno v:
Chest. 157:805-814
Regional and/or national severe asthma registries provide valuable country-specific information. However, they are often limited in scope within the broader definitions of severe asthma, have insufficient statistical power to answer many research que