Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Scarpa A"'
Autor:
David K. Chang, Roberto Salvia, Rosie Upstill-Goddard, Federica Marchesi, Alessandro Zerbi, Nigel B. Jamieson, Rita T. Lawlor, Stephan Dreyer, Anthony J. Gill, Jaswinder S. Samra, Euan J. Dickson, Andrew V. Biankin, Anubhav Mittal, Amber L. Johns, Aldo Scarpa, Georgios Gemenetzis, Kirsty Bisset, Fraser Duthie, Antonio Pea, Sarah Rae, Colin J. McKay, Alessandra Pulvirenti
Publikováno v:
Annals of Surgery. 277:e396-e405
Background: The long-term outcomes following surgical resection for pancreatic ductal adenocarcinoma (PDAC) remains poor, with only 20% of patients surviving 5 years after pancreatectomy. Patient selection for surgery remains sub-optimal largely due
Autor:
Estelle Collin, Ying Liu, Sara Trabulo, Rita T. Lawlor, Diana Behrens, David Osuna de la Peña, Daniela Loessner, Marianthi Tatari, Christopher Heeschen, Aldo Scarpa, Shreya Sharma, Mert Erkan, Alvaro Mata
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Patient-derived in vivo models of human cancer have become a reality, yet their turnaround time is inadequate for clinical applications. Therefore, tailored ex vivo models that faithfully recapitulate in vivo tumour biology are urgently needed. These
Autor:
Samik Upadhaya, Raffaella Casolino, Antonio Pea, Vincenzo Corbo, Chiara Braconi, Elisa Giovannetti, Paola Cappello, Geny Piro, Lorena Torroni, Miriam Martini, Andrew V. Biankin, David K. Chang, Aldo Scarpa, Claudio Bassi, Michele Milella, Carmine Carbone, Sara Lovisa, Jay Campbell, Yu Jia Xin
Publikováno v:
Gastroenterology
The PanCaCovid-19 Study Group 2021, ' Impact of COVID-19 on Pancreatic Cancer Research and the Path Forward ', Gastroenterology, vol. 161, no. 6, pp. 1758-1763 . https://doi.org/10.1053/j.gastro.2021.06.080
Gastroenterology, 161(6), 1758-1763. W.B. Saunders Ltd
The PanCaCovid-19 Study Group 2021, ' Impact of COVID-19 on Pancreatic Cancer Research and the Path Forward ', Gastroenterology, vol. 161, no. 6, pp. 1758-1763 . https://doi.org/10.1053/j.gastro.2021.06.080
Gastroenterology, 161(6), 1758-1763. W.B. Saunders Ltd
Autor:
Nicola Silvestris, Fulvia Colonna, Antonio Giovanni Solimando, Sabina Delcuratolo, Concetta Saponaro, Aldo Scarpa, Livia Fucci, Margherita Sonnessa, Claudio Luchini, Floriana Nappo, Antonella Argentiero, Sara Lonardi, Matteo Fassan, Oronzo Brunetti
Publikováno v:
Expert Opinion on Therapeutic Targets. 25:1007-1016
Background The improved immunological understanding revealed the tumor microenvironment as an appealing driver to restore the immune response against cancer cells resulting in a paradigm shift in the oncology field. However, the complexity of the tum
Autor:
Claudio Luchini, Sonia Alcalá, Manuel D. Gahete, María T. Cano, Raúl M. Luque, Pablo Cabezas-Sainz, Justo P. Castaño, Laura Sánchez, Emilia Alors-Perez, Rita T. Lawlor, Fernando Abollo-Jiménez, Ricardo Blazquez-Encinas, Sergio Pedraza-Arevalo, Andrea Mafficini, Laura Martin-Hijano, Cristina Viyuela-García, Marina E. Sánchez-Frías, Sebastián Ventura, Álvaro Arjona-Sánchez, Vicente Herrero-Aguayo, Aldo Scarpa, Alejandro Ibáñez-Costa, Juan M. Sánchez-Hidalgo, Juan Antonio Marin-Sanz, Bruno Sainz, Juan M. Jiménez-Vacas
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
© The Author(s) 2021.
[Background]: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, requiring novel treatments to target both cancer cells and cancer stem cells (CSCs). Altered splicing is emerging as both a novel cancer hall
[Background]: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, requiring novel treatments to target both cancer cells and cancer stem cells (CSCs). Altered splicing is emerging as both a novel cancer hall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3595702adbd34870bba805930ff53097
https://doi.org/10.21203/rs.3.rs-527836/v1
https://doi.org/10.21203/rs.3.rs-527836/v1
Autor:
Felice Giuliante, Enrico Vasile, Oronzo Brunetti, Chiara Alessandra Cella, Rossana Berardi, Stefano Cascinu, Anita Mangia, Sara Lonardi, Mario Scartozzi, Rita T. Lawlor, Daniele Santini, Fernando De Vita, Michele Milella, Claudio Luchini, Giuseppe Aprile, Antonella Argentiero, Stefania Tommasi, Andrea Casadei Gardini, Sandro Barni, Aldo Scarpa, Nicola Silvestris, Giovanni Brandi, Francesco Di Costanzo, Sara Delfanti, Claudio Doglioni, Vincenzo Mazzaferro, Ivana Cataldo, Evaristo Maiello, Paolo Marchetti
Publikováno v:
Tumori Journal. 105:353-358
Introduction:Exocrine pancreatic cancers include common type pancreatic ductal adenocarcinoma and cystic neoplasms, which account for 85% and 10% of cases, respectively. The remaining 5% are rare histotypes, comprising adenosquamous carcinoma, acinar
Autor:
Nicola Valeri, David Cunningham, Pietro Carotenuto, Somaieh Hedayat, Nigel B. Jamieson, Colin Rae, Albert Hallsworth, David Watkins, Anguraj Sadanandam, Matteo Fassan, Kyriakos Kouvelakis, Claudia Parisi, Sergio Xavier Azevedo, Francesco Amato, Vincenza Guzzardo, Ruwaida Begum, Ian Chau, Andrea Lanese, Kate Young, Vasiliki Michalarea, Maya Raj, Caterina Vicentini, Domenico Zito, Maria C. Previdi, Aldo Scarpa, Naureen Starling, Sheela Rao, Andrew Wotherspoon, Andrew V. Biankin, Ian Said-Huntingford, Andrea Lampis, David K. Chang, Paul Workman, Vladimir Kirkin, Francesco Sclafani, Jens C. Hahne, Rosie Upstill-Goddard, Chiara Braconi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
FOLFIRINOX, a combination of chemotherapy drugs (Fluorouracil, Oxaliplatin, Irinotecan -FOI), provides the best clinical benefit in pancreatic ductal adenocarcinoma (PDAC) patients. In this study we explore the role of miRNAs (MIR) as modulators of c
Publikováno v:
Applied Sciences, Vol 11, Iss 10077, p 10077 (2021)
Cancer is a worldwide burden resulting in millions of deaths each year. In particular, gastrointestinal tumors are life-threatening malignancies and one of the leading reasons for death in developed countries. Phytochemicals can be found in grains, v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f113f31c2f7cf89b7f47ef4b4c98fa74
http://hdl.handle.net/10447/523738
http://hdl.handle.net/10447/523738
Autor:
Aldo Scarpa, Giuseppe Malleo, Laura Maggino, Salvatore Paiella, Paola Capelli, Keith D. Lillemoe, Claudio Luchini, Motaz Qadan, Roberto Salvia, Carlos Fernandez-del Castillo, Cristina R. Ferrone, Giovanni Marchegiani, Mari Mino-Kenudson, Claudio Bassi
OBJECTIVE To reappraise the optimal number of examined lymph nodes (ELN) in pancreatoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC). SUMMARY BACKGROUND DATA The well-established threshold of 15 ELN in PD for PDAC is optimized for detec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1477291adaac3325f2cebc5c68b8be45
https://hdl.handle.net/11577/3476817
https://hdl.handle.net/11577/3476817
Autor:
Stephan B. Dreyer, Rosie Upstill-Goddard, Assya Legrini, Andrew V. Biankin, Nigel B. Jamieson, David K. Chang, Sarah Allison, Dario Beraldi, Euan Cameron, Susanna L. Cooke, Richard Cunningham, Stephan Dreyer, Paul Grimwood, Shane Kelly, John Marshall, Brian McDade, Elizabeth A. Musgrove, Donna Ramsay, Lisa Evers, Selma Rebus, Lola Rahib, Bryan Serrels, Colin J. McKay, Paul Westwood, Nicola Williams, Fraser Duthie, William Shen, Antonio Pea, Amber L. Johns, Anthony J. Gill, Lorraine A. Chantrill, Paul Timpson, Angela Chou, Marina Pajic, Tanya Dwarte, David Herrmann, Claire Vennin, Thomas R. Cox, Brooke Pereira, Shona Ritchiee, Daniel A. Reed, Cecilia R. Chambers, Xanthe Metcalf, Max Nobis, Gloria Jeong, Lara Kenyon, Ruth J. Lyons, Nicola Waddell, John V. Pearson, Ann-Marie Patch, Katia Nones, Felicity Newell, Pamela Mukhopadhyay, Venkateswar Addala, Stephen Kazakoff, Oliver Holmes, Conrad Leonard, Scott Wood, Sean M. Grimmond, Oliver Hofmann, Jaswinder S. Samra, Nick Pavlakis, Jennifer Arena, Hilda A. High, Ray Asghari, Neil D. Merrett, Amitabha Das, Peter H. Cosman, Kasim Ismail, Alina Stoita, David Williams, Allan Spigellman, Duncan McLeod, Judy Kirk, James G. Kench, Peter Grimison, Charbel Sandroussi, Annabel Goodwin, R. Scott Mead, Katherine Tucker, Lesley Andrews, Michael Texler, Cindy Forrest, Mo Ballal, David Fletcher, Maria Beilin, Kynan Feeney, Krishna Epari, Sanjay Mukhedkar, Nikolajs Zeps, Nan Q. Nguyen, Andrew R. Ruszkiewicz, Chris Worthley, John Chen, Mark E. Brooke-Smith, Virginia Papangelis, Andrew D. Clouston, Andrew P. Barbour, Thomas J. O’Rourke, Jonathan W. Fawcett, Kellee Slater, Michael Hatzifotis, Peter Hodgkinson, Mehrdad Nikfarjam, James R. Eshleman, Ralph H. Hruban, Christopher L. Wolfgang, Aldo Scarpa, Rita T. Lawlor, Vincenzo Corbo, Claudio Bassi
Publikováno v:
Gastroenterology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9df49d92ea32ac7a1cf88268d4685b
http://hdl.handle.net/11562/1056899
http://hdl.handle.net/11562/1056899