Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ye Zheng"'
Autor:
Ryan C. Gimple, Guoxin Zhang, Linjie Zhao, Leo J.Y. Kim, Jia Z. Shen, Cheryl Kim, Briana C. Prager, Xujun Wang, Jean A. Bernatchez, Xiang-Dong Fu, Jeremy N. Rich, Kailin Yang, Jair L. Siqueira-Neto, Deobrat Dixit, Zhixin Qiu, Lukas Chavez, Zhe Zhu, Deguan Lv, Ye Zheng, Denise Hinz, Zhengyu Liang, Charles Spruck, Xiuxing Wang, Chunyu Jin, Qiyuan Yang, Qiulian Wu, Lihua Min, Katherine A. Jones, Zhen Dong, Shruti Bhargava
Publikováno v:
Cancer Discov
Glioblastoma (GBM) is the most lethal primary brain cancer characterized by therapeutic resistance, which is promoted by GBM stem cells (GSC). Here, we interrogated gene expression and whole-genome CRISPR/Cas9 screening in a large panel of patient-de
Autor:
Yurong Wei, Xuexing Zheng, Wenwen Zheng, Xianwei Wang, Ye Zheng, Xianzhu Xia, Tong Xu, Zhongxin Zhao, Li Tian, Lele Liu, Hongbin He
Publikováno v:
Transboundary and Emerging Diseases. 68:1353-1362
Bovine ephemeral fever (BEF), caused by the bovine ephemeral fever virus (BEFV), is associated with an acute febrile infection in cattle and widespread in tropical and subtropical areas, leading to great economic losses to cattle and milk industry. H
Autor:
Wenkai Liu, Tong Xu, Wenwen Zheng, Li Tian, Ye Zheng, Chenjuan Shi, Hongmei Wang, Xuexing Zheng, Min Wang, Lele Liu, Xianzhu Xia, Hongbin He
Publikováno v:
Transboundary and Emerging Diseases. 69
Cystic echinococcosis (CE), caused by Echinococcus granulosus (E.granulosus), is a zoonosis with a worldwide distribution, resulting in heavy impact to public health and social economics. In this study, we generated a recombinant RABV expressing EG95
Autor:
Yuqiong Liang, Michael Downes, Theodore M. Kamenecka, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Ronald M. Evans, Thomas P. Burris, Chin-San Loo, Laura A. Solt, Sagar P Bapat, Mathias Leblanc, Han Cho, Christina L. Chang, Xuan Zhao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Th17 cells are a subset of T cells that produce interleukin 17 and other proinflammatory cytokines. They are involved in the development of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Previous studies illustr
Autor:
Chun-Ye Zheng, Hong-Feng Liang, Xiao-Dong Luo, Ai-Ping Gu, Qiao-Zhen Su, Jun Cai, Xin-Chun Zhang, Hua-Jun Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 502:269-275
Neuroinflammation plays a critical role in the process of neurodegenerative disorders, during which microglia, the principal resident immune cells in the central nervous system, are activated and produce proinflammatory mediators. Yin-Yang 1 (YY1), a
Autor:
Kelly A. Remedios, Mark H. Ginsberg, Jane E. Klann, Justine Lopez, Brian G. Petrich, Lauren A. Mack, John T. Chang, Stephanie H. Kim, Ye Zheng, Patrick J. Metz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 198, iss 12
Talin, a cytoskeletal protein essential in mediating integrin activation, has been previously shown to be involved in the regulation of T cell proliferation and function. In this study, we describe a role for talin in maintaining the homeostasis and
Autor:
Chun-Ye Zheng, Xin-Chun Zhang, Hong-Feng Liang, Ying-Bin Li, Jun Cai, Xiao-xin Bai, Hua-Jun Wang, Ai-Ping Gu, Xialin Tang
Publikováno v:
Neuropharmacology. 158
Yin-Yang 1 (YY1) has been identified as playing critical roles in multiple diseases. However, little is known regarding its roles and mechanisms in cerebral ischemia/reperfusion (I/R) injury. This study is aimed to explore the roles of YY1 in regulat
Autor:
Mathias Leblanc, Christopher Liddle, Ronald M. Evans, Annette R. Atkins, Ruth T. Yu, Jae Myoung Suh, Yuqiong Liang, Ye Zheng, Michael Downes, Sihao Liu, Carmen Zhou, Sungsoon Fang, Yang Zhang, Albert Cheng, Sagar P. Bapat
Publikováno v:
Nature. 528:137-141
Age-associated insulin resistance (IR) and obesity-associated IR are two physiologically distinct forms of adult-onset diabetes. While macrophage-driven inflammation is a core driver of obesity-associated IR, the underlying mechanisms of the obesity-
Autor:
Jailal N. G. Ablack, Mark H. Ginsberg, Jack D. Bui, Kelly A. Remedios, John T. Chang, Patrick J. Metz, Li-Fan Lu, Joseph M. Cantor, Jane E. Klann, Zhaoren He, Jocelyn G. Olvera, Stephanie H. Kim, Justine Lopez, Brian G. Petrich, Tiffani Tysl, Gene W. Yeo, Ye Zheng, Brigid S. Boland
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(12)
Maintenance of the regulatory T (Treg) cell pool is essential for peripheral tolerance and prevention of autoimmunity. Integrins, heterodimeric transmembrane proteins consisting of α and β subunits that mediate cell-to-cell and cell-to-extracellula
Autor:
Ronald M. Evans, Annette R. Atkins, Ye Zheng, Michael Downes, Weiwei Fan, Christopher Liddle, Ruth T. Yu, Nanhai He, Brian Henriquez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Regulatory T cells (Tregs) play a critical role in maintaining immune tolerance to self-antigens and in suppressing excessive immune responses that may cause collateral damage to the host. Unlike other CD4+ T cells, Tregs have a distinct