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Autor:
Uri Ladabaum
Publikováno v:
Gastroenterology. 164:861-865
Autor:
Jill M O'Brien, Aedheen J Regan, Vasileios T Papastavrou, Akhunzada Muhammad Aftab, Andrew C. Browning
Publikováno v:
RETINAL Cases & Brief Reports. 16:714-720
To characterize the progression of structural and functional changes in the retinas of a small cohort of unrelated patients with early late-onset retinal degeneration and evaluate these changes as potential biomarkers for future treatment trials.Best
Autor:
Eun Ji Nam, Tae Il Kim, Seung-Tae Lee, Saeam Shin, Ji Soo Park, Jung Woo Han, Sun Hwa Lee, Yoon Jung Lee, Hyung Seok Park
Publikováno v:
Cancer Research and Treatment. 54:1099-1110
Purpose The aim of the study was to evaluate the clinical implication of multigene panel testing of beyond BRCA genes in Korean patients with BRCA1/2 mutation-negative breast cancer.Materials and Methods Between 2016 and 2019, a total of 700 BRCA1/2
Autor:
Eva Miletínová, Monika Kliková, Tomas Novak, Radana Králová, Jitka Bušková, Jana Košťálová, Karolina Veldová
Publikováno v:
J Clin Sleep Med
STUDY OBJECTIVES: In some patients, it is difficult to correctly nosologically classify daytime sleepiness. Clinical manifestations may be nonspecific; on the basis of objective measures it is possible to determine the current severity of sleepiness,
Autor:
Nieraj Jain, Joshua M Barnett
Publikováno v:
RETINAL Cases & Brief Reports. 16:724-726
To describe a potential case of pentosan polysulfate maculopathy that seemed to manifest nearly 3 years after drug cessation.Complete ophthalmic examination, including multimodal fundus imaging, electroretinography, automated perimetry, and molecular
Publikováno v:
Internal Medicine Journal. 52:1196-1202
Background Less invasive inflammatory bowel disease (IBD) tests are increasingly being incorporated into clinical practice as adjuncts to endoscopy to monitor disease activity and guide optimal care. Little is known about patient perspectives of thes
Autor:
Yasutomo Suzuki, Satoko Nakayama, Masao Ichikawa, Yuka Toyama, Shigeo Akira, Yuki Endo, Yukihiro Kondo
Publikováno v:
Journal of Nippon Medical School. 89:222-226
Background Laparoscopic sacrocolpopexy (LSC) is an increasingly popular treatment for pelvic organ prolapse (POP) because of its low recurrence rate and safety. Although LSC may improve the voiding function, it may also lead to de novo stress urinary
Autor:
Orwa Albitar, Sabariah Noor Harun, Dzul Azri Mohamed Noor, Rama Ballouze, Siti Maisharah Sheikh Ghadzi
Publikováno v:
Therapeutic Drug Monitoring. 44:282-289
Cyclosporine is an essential component of many immunosuppressive regimens. However, its pharmacokinetic and pharmacodynamic (PKPD) modeling has not been widely investigated. This study aims to develop a time-dissociated PKPD model of cyclosporine in
Autor:
Federico Innocenti, Spinel Karas
Publikováno v:
JCO Oncology Practice. 18:270-277
Irinotecan is an anticancer agent widely used for the treatment of solid tumors, including colorectal and pancreatic cancers. Severe neutropenia and diarrhea are common dose-limiting toxicities of irinotecan-based therapy, and UGT1A1 polymorphisms ar
Autor:
Karen C. Wells, Shayna M. Cheek, John F. Curry, Adrienne Banny Inscoe, Yifrah Kaminer, Allison E. Meyer, Rebecca H. Burke, David B. Goldston, Grace Chan
Publikováno v:
J Am Acad Child Adolesc Psychiatry
OBJECTIVE: To investigate prevalence and predictors of early depression response (EDR) in adolescents with substance use and depression receiving cognitive-behavioral therapy (CBT) for substance use; and to test the efficacy of supplemental CBT targe