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Autor:
Tršan, Tihana, Busche, Andreas, Abram, Maja, Babić Čač, Marina, Golemac, Mijo, Tomić, Adriana, Krmpotić, Astrid, Messerle, Martin, Jonjić, Stipan
INTRODUCTION. NKG2D is a potent activating receptor expressed by cells of innate and adaptive immunity that recognizes cell surface molecules structurally related to MHC-I proteins induced by infection or other type of cellular stress. Engagement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::fa9e25f7fcc63ff11b4a4ab847ec2004
https://www.bib.irb.hr/594755
https://www.bib.irb.hr/594755
Autor:
Tršan, Tihana, Busche, Andreas, Babić, Marina, Tomić, Adriana, Golemac, Mijo, Lemmermann, Niels, Brinkmann, Melanie, Jäger, Wiebke, Abram, Maja, Krmpotić, Astrid, Messerle, Martin, Jonjić, Stipan
There is a large number of pathogens for which post-infection acquired immunity does not fully protect against re-infection and disease. Therefore, vaccines which offer superior protection compared to the one following natural infection are needed. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::4eb6204cb1ec8ed9a8eb30aebe40c5c7
https://www.bib.irb.hr/603503
https://www.bib.irb.hr/603503
Autor:
Slavuljica Irena, Busche Andreas, Babic Marina, Mitrovic Maja, Gasparovic Iva, Cekinovic Djurdjica, Markova Car Elitza, Pernjak Pugel Ester, Cikovic Ana, Juranic Lisnic Vanda, Britt William, Koszinovski Ulrich, Messerle Martin, Krmpotic Astrid, Jonjic Stipan
The authors propose a model where an engineered cytomegalovirus serves as a potential vaccine. Namely, a ligand for the strong activating NK cell receptors is inserted into a CMV-BAC, and this feature makes the virus strongly attenuated in vivo in bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::152f87ff53a9b379aa9bca729f1aade6
https://www.bib.irb.hr/493811
https://www.bib.irb.hr/493811
Autor:
Slavuljica, Irena, Busche, Andreas, Babić, Marina, Mitrović, Maja, Gašparović, Iva, Cekinović, Đurđica, Markova Car, Elitza, Pernjak Pugel, Ester, Ciković, Ana, Juranić Lisnić, Vanda, Messerle, Martin, Krmpotić, Astrid, Jonjić, Stipan.
Cytomegalovirus (CMV) is a major viral cause of morbidity and mortality after congenitaly infected and immunocompromised individuals, such as transplant recipiens and HIV-infected pacients. This is why developing an effective and safe HCMV vaccine is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::b3dddf3ecfb38f58fb00cc62ef940318
https://www.bib.irb.hr/560570
https://www.bib.irb.hr/560570
Autor:
Gašparović, Iva, Busche, Andreas, Cekinović, Đurđica, Babić, Marina, Slavuljica, Irena, Krmpotić, Astrid, Messerle, Martin, Jonjić, Stipan
Natural killer (NK) cells offer early antiviral protection. Their dominant activating receptor is NKG2D, also present as a co-receptor on CD8+ T cells. Its role in the function of CD8+ T cells is still insufficiently defined. NKG2D ligands ; MULT-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::c4148b9072b797959817b6a3c8d4a927
https://www.bib.irb.hr/373316
https://www.bib.irb.hr/373316
Autor:
Rodríguez-Martín, Sara, Juranić Lisnić, Vanda, Livingston, Andrew, Jonjić, Stipan, Messerle, Martin, Angulo, Ana, Krmpotić, Astrid, Ghazal, Peter
One of the most famous cytokines, tumor necrosis factor (TNF), shows a vast spectrum of bioactivities influencing majority of cell types. Produced mostly by macrophages, it is considered to be a major mediator of inflammation and cellular immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::9374ed907722ce3296f16cffccfaee8b
https://www.bib.irb.hr/478056
https://www.bib.irb.hr/478056
Autor:
Mans, Janet, Natarajan, Kannan, Babić, Marina, Messerle, Martin, Šimić, Hrvoje, Krmpotić, Astrid, Jonjić, Stipan, Margulies, David
It is shown that MCMV m153 is expressed on the surface of infected cells and possesses unusual MHC class I-like form.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::33a91ad5eaa28dcd90842b6964bfbed1
https://www.bib.irb.hr/347253
https://www.bib.irb.hr/347253
Autor:
Koszinowski, H. Ulrich, Reddehase, Mathias , Keil, G.M., Volkmer, H., Jonjić, Stipan, Messerle, Martin, del Val, Margerita, Mutter, Wolfgang, Munch, K., Buhler, B.
The infection of the mouse with murine cytomegalovirus (MCMV) served as a model system to understand the biology of human CMV infection. The contribution of cytolytic T lymphocytes (CTL) to the recovery from infection was studied. Protection against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::9b1603ea431b81ef6fecb1f90149dfa7
https://www.bib.irb.hr/184300
https://www.bib.irb.hr/184300