Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Reinaldo N. Takahashi"'
Publikováno v:
Neuroscience letters. 622
Understanding the mechanisms responsible for nonmotor manifestations of Parkinson's disease (PD) is crucial in the search for new therapeutic approaches. The aim of the present study was to evaluate the time course of behavioral, neurochemical, and m
Autor:
Jorge Camilo Flório, Rui Daniel Prediger, Reinaldo N. Takahashi, Pablo Pandolfo, Luciano C. Batista, Rodrigo Medeiros
Publikováno v:
Experimental Neurology. 202:391-403
Many studies have shown that deficits in olfactory and cognitive functions precede the classical motor symptoms seen in Parkinson's disease (PD) and that olfactory testing may contribute to the early diagnosis of this disorder. Although the primary c
Autor:
Edmar Miyoshi, Claudio Da Cunha, Milton Camplessei, Samantha Wietzikoski, Rodolfo Silveira, Reinaldo N. Takahashi
Publikováno v:
Brain research bulletin. 58(1)
A lesion in the substantia nigra pars compacta (SNc) of rats induced by intra-nigral administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) caused specific loss of dopamine and its nonconjugated metabolites in the dorsal striatum and i