Zobrazeno 1 - 10
of 30
pro vyhledávání: '"David G. Hoel"'
Autor:
David G. Hoel, Mulugeta Gebregziabher
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 15:858-875
The statistical analysis of cancer bioassay data has historically depended on the pathological determination of the experimental animal's cause of death. The poly-k statistical test has provided a method of statistical analysis of animal bioassay dat
Publikováno v:
Mathematical Biosciences. 149:107-136
When ionizing radiation strikes a cell it induces DNA double strand breaks (DSBs). Subsequently, some of the DSBs misrejoin and thus cause alterations in the size distribution of the DNA fragments. We derive a system of non-linear integro-differentia
Autor:
David G. Hoel, Gerald R. Chase
Publikováno v:
Biometrika. 62:329-334
SUMMARY The effect of small errors of dilution is shown to be sizeable when serial dilutions are required to estimate particle concentrations. Optimal dilution designs are given. The error effect and optimal design are also investigated for ratios of
Publikováno v:
Biometrika. 62:195-200
We examine results produced by a new likelihood stopping rule for terminating clinical trials, designed to choose the better of two competing dichotomous treatments, or to decide that they are equal. A method for adaptive assignment is also discussed
Publikováno v:
Communications in Statistics - Theory and Methods. 6:777-788
A method is presented for the sequential analysis of experiments involving two treatments to which response is dichotomous. Composite hypotheses about the difference in success probabilities are tested, and covariate information is utilized in the an
Autor:
Takashi Yanagawa, David G. Hoel
Publikováno v:
Journal of the American Statistical Association. 81:1095-1099
The testing of chemicals for carcinogenic activity in lifetime rodent bioassays has produced a large amount of data on a few strains of mice and rats. Because of the use of fixed protocols in repeated experiments, the opportunity presents itself for
Autor:
David G. Hoel, Robert I. Jennrich
Publikováno v:
Journal of Statistical Computation and Simulation. 20:311-322
Life table analysis techniques in epidemiology depend upon the asymptotic properties of the statistical test methods employed. In some instances, the statistical procedures indicate highly significant results which are, in reality, unjustified. The p
Autor:
Kenny S. Crump, David G. Hoel
Publikováno v:
Biometrika. 61:237-252
SUMMARY A number of mathematical models for cell populations in which mutations are occurring are studied and compared by viewing the models as filtered Poisson processes. Based upon these models, a statistical analysis is given of the mutant accumul
Autor:
Kantilal M. Patel, David G. Hoel
Publikováno v:
Journal of the American Statistical Association. 68:615-620
A measure of interaction in factorial experiments is introduced and the problem of estimating it and testing it for nullity is considered. The asymptotic power efficiencies are studied and Monte Carlo power comparisons are made when samples are drawn
Publikováno v:
Journal of Statistical Computation and Simulation. 3:299-313
We consider the problem of choosing the best of k binomial populations when the time to response is non zero. Several sampling schemes are discussed, with an aim to making as few trials as possible with the poorer treatments, as would be a desideratu