Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Dawn M, Elliott"'
Autor:
Miltiadis H. Zgonis, Olivia C. O'Reilly, Sonia Bansal, Dawn M. Elliott, Robert L. Mauck, Niobra M. Keah, John M. Peloquin
Publikováno v:
J Orthop Res
The knee menisci are comprised of two orthogonal collagenous networks – circumferential and radial – that combine to enable efficient load bearing by the tissue in adults. Here, we assessed how the structural and functional characteristics of the
Publikováno v:
JOR Spine, Vol 4, Iss 2, Pp n/a-n/a (2021)
JOR Spine
JOR Spine
Finite element models of the intervertebral disc are used to address research questions that cannot be tested through typical experimentation. A disc model requires complex geometry and tissue properties to be accurately defined to mimic the physiolo
Publikováno v:
Ann Biomed Eng
One of the most common bath solutions used in musculoskeletal mechanical testing is phosphate buffered saline (PBS). In tendon, swelling induced by physiological PBS results in decreased tendon modulus and induces microstructural changes. It is criti
Autor:
Lachlan J. Smith, Neil R. Malhotra, Prateek Agarwal, Robert L. Mauck, Dawn M. Elliott, Weiliam Chen, George R. Dodge, Thomas P. Schaer, Sarah E. Gullbrand, Justin R. Bendigo
Publikováno v:
Acta Biomaterialia. 60:201-209
Degeneration of the intervertebral discs is a progressive cascade of cellular, compositional and structural changes that is frequently associated with low back pain. As the first signs of disc degeneration typically arise in the disc’s central nucl
Autor:
Edward J. Vresilovic, Brent L. Showalter, Alexander C. Wright, Dawn M. Elliott, Neil R. Malhotra, Amy A. Claeson, James C. Gee
Publikováno v:
J Biomech Eng
Nucleotomy is a common surgical procedure and is also performed in ex vivo mechanical testing to model decreased nucleus pulposus (NP) pressurization that occurs with degeneration. Here, we implement novel and noninvasive methods using magnetic reson
Tendon’s hierarchical structure allows for load transfer between its fibrillar elements at multiple length scales. Tendon microstructure is particularly important, because it includes the cells and their surrounding collagen fibrils, where mechanic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc5b08fdb7778fb95b855b0f9525cbc
https://doi.org/10.1101/547281
https://doi.org/10.1101/547281
Publikováno v:
Journal of Biomechanical Engineering. 141
Fibrous soft tissues are biopolymeric materials that are made of extracellular proteins, such as different types of collagen and proteoglycans, and have a high water content. These tissues have nonlinear, anisotropic, and inelastic mechanical behavio
Publikováno v:
Journal of Orthopaedic Research. 34:1307-1315
The inter-lamellar matrix (ILM) has an average thickness of less than 30 µm and lies between adjacent lamellae in the annulus fibrosus (AF). The microstructure and composition of the ILM have been studied in various anatomic regions of the disc; how
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine. 29:711-722
Here we develop a three-dimensional analytic model for MR image contrast of collagen lamellae in the annulus fibrosus of the intervertebral disc of the spine, based on the dependence of the MRI signal on collagen fiber orientation. High-resolution MR
Autor:
Brent L. Showalter, Edward J. Vresilovic, Daniel H. Cortes, John F. DeLucca, Dawn M. Elliott, John M. Peloquin, Jonathon H. Yoder, James C. Gee, Nathan T. Jacobs, Alexander C. Wright
Publikováno v:
Journal of Orthopaedic Research. 34:1264-1273
Tissue strain is an important indicator of mechanical function, but is difficult to noninvasively measure in the intervertebral disc. The objective of this study was to generate a disc strain template, a 3D average of disc strain, of a group of human