Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chih-Wei Liu"'
Publikováno v:
Toxics, Vol 7, Iss 3, p 41 (2019)
The proposal of the “exposome” concept represents a shift of the research paradigm in studying exposure-disease relationships from an isolated and partial way to a systematic and agnostic approach. Nevertheless, exposome implementation is facing
Externí odkaz:
https://doaj.org/article/9aeb306ecc1c4e08934bdd9ab862565a
Autor:
Wenxin Hu1,2,3, Chih-Wei Liu4, Jiménez, Jessica A.5, McCoy, Eric S.1,2, Yun-Chung Hsiao4, Weili Lin6, Engel, Stephanie M.7, Kun Lu4, Zylka, Mark J.1,2,3 zylka@med.unc.edu
Publikováno v:
Environmental Health Perspectives. Feb2022, Vol. 130 Issue 2, p027013-1-027013-9. 9p. 2 Diagrams, 1 Chart, 4 Graphs.
Publikováno v:
Toxicological Sciences
Vinyl acetate monomer (VAM) is heavily used to synthesize polymers. Previous studies have shown that inhaled VAM, being metabolized to acetaldehyde, may form DNA adducts including N2-ethylidene-deoxyguanosine (N2-EtD-dG), which may subsequently cause
Publikováno v:
ACS Omega, Vol 6, Iss 12, Pp 8094-8103 (2021)
ACS Omega
ACS Omega
Recent evidence indicates that tryptophan metabolites and neurotransmitters are potential mediators of the microbiome–gut–brain interaction. Here, a high-resolution ultra-high performance liquid chromatography-electrospray ionization tandem mass
Publikováno v:
Chemical research in toxicology. 35(1)
Cancer remains the second most frequent cause of death in human populations worldwide, which has been reflected in the emphasis placed on management of risk from environmental chemicals considered to be potential human carcinogens. The formation of D
Publikováno v:
Analytical Chemistry. 90:1081-1086
Glycated proteins are emerging as good indicators for diabetes and age related diseases. However, the platform for analysis of glycated proteome has been relatively less well established. We here introduce an online 2D-LC-HCD-MS/MS platform for compr
Autor:
Jiapeng Leng, Liang Chi, Pengcheng Tu, Jingchuan Xue, Hongyu Ru, Yunjia Lai, Kun Lu, Chih-Wei Liu
Publikováno v:
Journal of proteome research. 18(3)
Arsenic contamination in drinking water has been a worldwide health concern for decades. In addition to being a well-recognized carcinogen, arsenic exposure has also been linked to diabetes, neurological effects, and cardiovascular diseases. Recently
Autor:
Yongquan Lai, Chih-Wei Liu, Rui Yu, Jiapeng Leng, Kun Lu, James A. Swenberg, Hadley J. Hartwell, Wanda Bodnar
Publikováno v:
Arch Toxicol
As a widespread industrial chemical, formaldehyde carcinogenicity has been highly controversial. Meanwhile, formaldehyde is an essential metabolite in all living cells. Previously, we have demonstrated exogenous formaldehyde causes DNA adducts in a n
Publikováno v:
Toxics, Vol 7, Iss 3, p 41 (2019)
Toxics
Toxics
The proposal of the “exposome” concept represents a shift of the research paradigm in studying exposure-disease relationships from an isolated and partial way to a systematic and agnostic approach. Nevertheless, exposome implementation is facing
Autor:
Jiapeng Leng, Kun Lu, James A. Swenberg, Hadley J. Hartwell, Liang Chi, Xu Tian, Chih-Wei Liu
Publikováno v:
Chemical research in toxicology. 31(5)
Genomic instability caused by DNA-protein cross-link (DPCs)-induced DNA damage is implicated in disease pathogenesis, aging, and cancer development. The covalent linkages between DNA and protein are induced by chemical reactions catalyzed by the endo