Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Silvia Veneroni"'
Publikováno v:
British Journal of Cancer
To obtain a more integrated understanding of the different breast cancer phenotypes and to investigate whether bio-molecular profiles can distinguish between specific histotypes, we explored the interrelations among several biologic variables indicat
Autor:
E. Benini, Silvia Veneroni, Antonio Maucione, Monica Leutner, Umberto Veronesi, Roberto Zucali, A Luisi, Rado Kenda, Maria Grazia Daidone, Rosella Silvestrini
Publikováno v:
JNCI Journal of the National Cancer Institute. 89:639-645
BACKGROUND In clinical breast cancer research, the utility of certain biomarkers as predictors of response to surgery, chemotherapy, or hormonal therapy has been studied intensively. Much less research has been done on the relevance of biologic predi
Autor:
Bruno Salvadori, P Squicciarini, E. Benini, Silvia Veneroni, Rosella Silvestrini, Maria Grazia Daidone, Gorana Tomasic
Publikováno v:
Scopus-Elsevier
BACKGROUND AND PURPOSE The tumor-suppressor gene TP53 and the proto-oncogene bcl-2 encode, respectively, for a nuclear phosphoprotein and for a mitochondrial protein involved in multiple cellular functions. The proteins provide prognostic information
Autor:
Salvatore Andreola, Rosella Silvestrini, Silvia Veneroni, Maria Grazia Daidone, Cristina Brambilla, Marinella Mastore, A Luisi, Umberto Veronesi, Marco Greco, E. Benini, Laura Ferrari
Publikováno v:
International Journal of Cancer. 61:301-305
The profiles of functional (proliferative rate and cell distribution in the cell cycle) and phenotypic (nuclear DNA content and hormone receptor status) biological markers and the expression of P53 and Bcl-2 proteins were prospectively evaluated in b
Autor:
Silvia Veneroni, C. Pellizzaro, Federico Ambrogi, Saro Oriana, Patrizia Boracchi, Ettore Marubini, Maria Grazia Daidone, Danila Coradini, Elia Biganzoli, Roberta Erdas
Publikováno v:
British Journal of Cancer
In 212 postmenopausal women with node-positive oestrogen receptor-positive (ER(LBA)) breast cancer subjected to radical surgery and adjuvant tamoxifen, the risk of 6-year relapse increased with increasing values of intratumoral vascular endothelial g
Autor:
Umberto Veronesi, Patrizia Boracchi, Maria Grazia Daidone, Rosella Silvestrini, Maura Mezzetti, Franco Rilke, E. Benini, Silvia Veneroni, Giovanni Di Fronzo
Publikováno v:
Scopus-Elsevier
BACKGROUND The bcl-2 gene (also known as BCL2) encodes for a mitochondrial protein thought to prevent apoptosis of normal cells. The protein has been detected by immunohistochemical procedures in hormonally regulated epithelia. PURPOSE We analyzed th
Autor:
E. Benini, Silvia Veneroni, Vera Cappelletti, G. Di Fronzo, Maria Grazia Daidone, Umberto Veronesi, Patrizia Boracchi, Rosella Silvestrini
Publikováno v:
Scopus-Elsevier
BACKGROUND At present, most decisions concerning the use of adjuvant therapy in lymph node-negative breast cancer patients are made on the basis of traditional factors such as tumor size, nodal status, and histopathologic features. However, prognosti
Autor:
Angelo Paradiso, Rosella Silvestrini, Maria Grazia Daidone, Vera Cappelletti, M. Correale, Giovanni Di Fronzo, Dino Amadori, Angela Riccobon, Silvia Veneroni
Publikováno v:
Breast Cancer Research and Treatment. 26:7-13
The expression of cathepsin D was evaluated by immunohistochemistry on histologic sections from formalin-fixed samples in a series of 436 primary breast cancers. The fraction of cathepsin D-positive tumor cells was not related to tumor size or hormon
Publikováno v:
Critical reviews in oncology/hematology. 45(3)
A biological characterisation carried out on 14,007 primary breast cancers provided evidence in favour of a relation between advanced age and favourable features (positivity for oestrogen/progesterone receptors, low proliferative rate, absence of p53
Autor:
E. Benini, Gabriele Martelli, Maria Grazia Daidone, Rosella Silvestrini, Gorana Tomasic, G. De Palo, Silvia Veneroni, A Luisi
Publikováno v:
British Journal of Cancer
Scopus-Elsevier
Scopus-Elsevier
The predictive role of tumour proliferative rate and expression of p53, bcl-2 and bax proteins, alone and in association with tumour size, nodal involvement and oestrogen receptors (ER), was analysed on 145 elderly patients (≥70 years of age) with