Zobrazeno 1 - 10
of 6 402
pro vyhledávání: '"valproic acid"'
Publikováno v:
Brain Research Bulletin. 191:20-29
This study aimed to explore the effect of concomitant use of Furosemide (FRS) and Valproic acid (VPA), demonstrating anti-inflammation efficacy, on epilepsy, and its underlying mechanism.Twenty-five adult male Wistar rats were divided into five group
Autor:
Emma Salisbury, Sam Topp
Publikováno v:
BMJ case reports. 14(7)
Lithium is an effective mood stabiliser used to treat bipolar affective disorder (BPAD); however, it can also adversely affect the kidneys, causing acute toxic effects, nephrogenic diabetes insipidus, chronic renal dysfunction and end-stage kidney di
Autor:
Rubal Singla, Abhishek Mishra, Rupa Joshi, Phulen Sarma, Rohit Kumar, Gurjeet Kaur, Amit Raj Sharma, Ashish Jain, Ajay Prakash, Alka Bhatia, Bikash Medhi
Publikováno v:
Brain Research Bulletin. 190:122-133
Dysregulated GABAergic signaling is reported in Autism Spectrum disorder (ASD). In the present study, we evaluated a GABA structural mimicker homotaurine (HT) via in-silico docking and investigated the therapeutic efficacy of this drug to ameliorate
Autor:
Jigar Patel, Ivan Berezowski, Maryann Mazer-Amirshahi, Sarah E. Frasure, Quincy K. Tran, Ali Pourmand
Publikováno v:
The Journal of Emergency Medicine. 63:651-655
Valproic acid (VPA) is a common antiepileptic drug that is also used routinely for various psychiatric disorders. VPA toxicity typically manifests as central nervous system depression, while hyperammonemic encephalopathy and hepatotoxicity are potent
Publikováno v:
Expert Review of Clinical Pharmacology. 15:1479-1486
Studies that evaluated vestibular function with epilepsy are fewer than auditory studies. We assessed vestibular function in children with epilepsy in inter-ictal period.This cross-sectional study included 35 children with generalized epilepsy (boys=
Autor:
Zlatan Coralic, Jaideep Kapur, Kent R. Olson, James M. Chamberlain, Daniel Overbeek, Robert Silbergleit
Publikováno v:
Annals of Emergency Medicine. 80:194-202
We describe a subset of patients with toxin-related precipitants of seizures/status epilepticus enrolled in the Established Status Epilepticus Treatment Trial (ESETT).The ESETT was a prospective, double-blinded, adaptive trial evaluating levetiraceta
Publikováno v:
Brain and Development. 44:546-550
Adrenocorticotropic hormone (ACTH) therapy is a first-line treatment for infantile spasms, which may rarely cause intracranial hemorrhage. However, the changes in blood coagulation during ACTH therapy are poorly understood, with little description in
Autor:
Ole Köhler-Forsberg, Louisa G Sylvia, Michael Thase, Joseph R Calabrese, Mauricio Tohen, Charles L Bowden, Melvin McInnis, Dan V Iosifescu, James H Kocsis, Edward S Friedman, Terence A Ketter, Susan L McElroy, Richard C Shelton, Vicki Fung, Michael J Ostacher, Andrew A Nierenberg
Publikováno v:
Köhler-Forsberg, O, Sylvia, L G, Thase, M, Calabrese, J R, Tohen, M, Bowden, C L, McInnis, M, Iosifescu, D V, Kocsis, J H, Friedman, E S, Ketter, T A, McElroy, S L, Shelton, R C, Fung, V, Ostacher, M J & Nierenberg, A A 2023, ' Lithium plus antipsychotics or anticonvulsants for bipolar disorder : Comparing clinical response and metabolic changes ', Australian and New Zealand Journal of Psychiatry, vol. 57, no. 1, pp. 93-103 . https://doi.org/10.1177/00048674221077619
Köhler-Forsberg, O, Sylvia, L G, Thase, M, Calabrese, J R, Tohen, M, Bowden, C L, McInnis, M, Iosifescu, D V, Kocsis, J H, Friedman, E S, Ketter, T A, McElroy, S L, Shelton, R C, Fung, V, Ostacher, M J & Nierenberg, A A 2023, ' Lithium plus antipsychotics or anticonvulsants for bipolar disorder : Comparing clinical response and metabolic changes ', The Australian & New Zealand Journal of Psychiatry, vol. 57, no. 1, pp. 93-103 . https://doi.org/10.1177/00048674221077619
Köhler-Forsberg, O, Sylvia, L G, Thase, M, Calabrese, J R, Tohen, M, Bowden, C L, McInnis, M, Iosifescu, D V, Kocsis, J H, Friedman, E S, Ketter, T A, McElroy, S L, Shelton, R C, Fung, V, Ostacher, M J & Nierenberg, A A 2023, ' Lithium plus antipsychotics or anticonvulsants for bipolar disorder : Comparing clinical response and metabolic changes ', The Australian & New Zealand Journal of Psychiatry, vol. 57, no. 1, pp. 93-103 . https://doi.org/10.1177/00048674221077619
Objective: Patients with bipolar disorder treated with lithium often require additional antipsychotics or anticonvulsants. However, the comparative effectiveness and safety of these agents as add-on to lithium has not been studied. Methods: This seco
Autor:
Anoop Kumar, Akash Sharma
Publikováno v:
Acta Neurologica Scandinavica. 146:623-627
Clobazam is a well-known benzodiazepine used as an anti-anxiety drug as well as an anti-epileptic, particularly for patients who are not responding to first-line treatments. Recent case reports have indicated the association of clobazam with drug rea
Autor:
Meltem Alpay, Ferruh Yucel
Publikováno v:
International Journal of Developmental Neuroscience. 82:606-614
In this study, 32 male Sprague-Dawley rats (8 for each group) were used in total to examine the effects of valproic acid on rat cerebellum. It was determined that the experimental group received valproic acid (600 mg/kg) on embryonic day 15 and postn