Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yong Sang Jo"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Fear extinction is an active learning process whereby previously established conditioned responses to a conditioned stimulus are suppressed. Paradoxically, when extinction training is performed immediately following fear acquisition, the extinction m
Publikováno v:
Behavioural Brain Research. 318:12-17
The lateral habenula (LHb) is an epithalamic brain structure that provides strong projections to midbrain monoaminergic systems that are involved in motivation, emotion, and reinforcement learning. LHb neurons are known to convey information about av
Summary Generalized fear is a maladaptive behavior in which non-threatening stimuli elicit a fearful response. Here, we demonstrate that discrimination between predictive and non-predictive threat stimuli is highly sensitive to probabilistic discount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a7759a716d0a758cd660cc1defcced
https://europepmc.org/articles/PMC6226002/
https://europepmc.org/articles/PMC6226002/
Autor:
Sheri J. Y. Mizumori, Yong Sang Jo
Publikováno v:
Cerebral Cortex. 26:4057-4068
Growing evidence indicates that midbrain dopamine (DA) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute errors in reward prediction. Here we investigated how 2 major prefrontal subregions, the orbit
Publikováno v:
Neurobiology of Learning and Memory. 117:93-108
A role for the hippocampus in memory is clear, although the mechanism for its contribution remains a matter of debate. Converging evidence suggests that hippocampus evaluates the extent to which context-defining features of events occur as expected.
Autor:
Bryan B. Gore, Mrinalini Hoon, Yong Sang Jo, Rachel O.L. Wong, Larry S. Zweifel, Weining Lu, Samara M. Miller, Christina A Sanford, Avery C. Hunker, Madison A. Baird
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The maintenance of excitatory and inhibitory balance in the brain is essential for its function. Here we find that the developmental axon guidance receptor Roundabout 2 (Robo2) is critical for the maintenance of inhibitory synapses in the adult ventr
Autor:
Scott H. Soderling, Hyun Uk Kim, Yong Sang Jo, Soon Taek Hong, Eunjoo Kim, Eun Hye Park, Seung Baek Han, Woong Sun, Il Hwan Kim, Hyun Kim, Soon Kwon Park, Hee-Sup Shin
Publikováno v:
The Journal of Neuroscience. 29:14039-14049
Activity-dependent alterations of synaptic contacts are crucial for synaptic plasticity. The formation of new dendritic spines and synapses is known to require actin cytoskeletal reorganization specifically during neural activation phases. Yet the si
Autor:
June-Seek Choi, Yong Sang Jo
Publikováno v:
Neurobiology of learning and memory. 109
The medial prefrontal cortex (mPFC) has been suggested to play a crucial role in retrieving detailed contextual information about a previous learning episode in response to a single retrieval cue. However, few studies investigated the neurochemical m
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(19)
Dopamine (DA) cells have been suggested to signal discrepancies between expected and actual rewards in reinforcement learning. DA cells in the ventral tegmental area (VTA) receive direct projections from the medial prefrontal cortex (mPFC), a structu
Autor:
Inah Lee, Yong Sang Jo
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(29)
The hippocampus and the perirhinal cortex (PR) are reciprocally connected both directly and indirectly via the entorhinal cortex. Although it has been hypothesized that the two regions should have intimate functional interactions with each other on t