Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Yong J. Lee"'
Autor:
Lisa Bailey, David L. Bartlett, Xinxin Song, Se Hoon Hong, William T. Kwon, Yong J. Lee, Yong Tae Kwon, Per H. Basse
Publikováno v:
Molecular Cancer Therapeutics. 15:1591-1601
Since its discovery in 1995, TNF-related apoptosis-inducing ligand (TRAIL) has sparked growing interest among oncologists due to its remarkable ability to induce apoptosis in malignant human cells, but not in most normal cells. However, one major dra
Autor:
Eun Kyung Lee, Seul Gi Yoon, Chang Sik Choi, Hanho Shin, Dong H. Son, Jung Hyuck Park, Ki Woo Kim, Jung Eun Kim, Jun Gi Rho, Wook Kim, Ji H. Han, Juhwan Yoon, Je K. Seong, Il Yong Kim, Byung Joo Song, Yong J. Lee
Publikováno v:
Diabetes, obesitymetabolism. 20(9)
Aim To analyze the metabolic parameters and adipose tissue inflammation via NLRP3 inflammasome following chronic treatment of mouse models of obesity with AJ5018 as the peripherally restricted cannabinoid 1 receptor (CB1R) antagonist. Materials and m
Publikováno v:
Molecular Cancer Research. 10:1567-1579
Colorectal cancer is the third leading cause of cancer-related mortality in the world. The main cause of death because of colorectal cancer is hepatic metastases, which can be treated using isolated hepatic perfusion (IHP), allowing treatment of colo
Autor:
Marco A. Alcala, Hyounsoo Uh, Yong J. Lee, Ruth A. Modzelewski, Shu Ying Kwan, Kristy A. Gogick, David L. Bartlett, Stéphane Petoud, Adam R. Meier, Matthias Bischof, Chad M. Shade, Timothy G. Strein, Charles K. Brown, Zachary P. Thompson
Publikováno v:
Biomaterials
Biomaterials, Elsevier, 2011, 32 (35), pp.9343-52. ⟨10.1016/j.biomaterials.2011.07.076⟩
Biomaterials, Elsevier, 2011, 32 (35), pp.9343-52. ⟨10.1016/j.biomaterials.2011.07.076⟩
International audience; We have created a dendrimer complex suitable for preferential accumulation within liver tumors and luminescence imaging by substituting thirty-two naphthalimide fluorophores on the surface of the dendrimer and incorporating ei
Autor:
Marco A. Alcala, Jinsang Yoo, David L. Bartlett, Byeong-Chel Lee, Bae-Hang Park, Dae Hee Lee, Kyung Soo Park, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 110:1073-1081
Approximately 25% of patients with colorectal cancer develop metastases to the liver, and surgery is currently the best treatment available. But there are several patients who are unresectable, and isolated hepatic perfusion (IHP) offers a different
Publikováno v:
British Journal of Pharmacology. 157:1189-1202
Background and purpose: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptotic death in a variety of cancer cells without marked toxicity to most normal cells. We previously reported that wogonin, a potent anticancer agen
Autor:
Dae Hee Lee, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 105:546-553
Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit the proliferation of cancer cells and induce the accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha) in normoxia. In this study, under hypoxic conditions (1% O(2)),
Publikováno v:
Biochemical Pharmacology. 75:2345-2355
The aim of this study was to investigate the effect of quercetin, a flavonoid, on the apoptotic pathway in a human prostate cell line (LNCaP). We observed that treatment of cells for 24h with quercetin-induced cell death in a dose-dependent manner. A
Publikováno v:
Biochemical Pharmacology. 75:2020-2033
We observed that treatment of prostate cancer cells for 24 h with wogonin, a naturally occurring monoflavonoid, induced cell death in a dose- and time-dependent manner. Exposure of wogonin to LNCaP cells was associated with increased intracellular le
Autor:
Jae J. Song, Yong J. Lee
Publikováno v:
Cellular Signalling. 20:892-906
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been shown to induce apoptosis through caspase activation in a number of cancer cell lines while displaying minimal or no toxicity on normal cells, suggesting that this protein may h