Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Xiaofeng Tian"'
Autor:
Yue Wang, Yan Zhao, Zhecheng Wang, Ruimin Sun, Boyang Zou, Ruixi Li, Deshun Liu, Musen Lin, Junjun Zhou, Shili Ning, Xiaofeng Tian, Jihong Yao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Pyroptosis is a newly discovered form of cell death. Peroxiredoxin 3 (PRX3) plays a crucial role in scavenging reactive oxygen species (ROS), but its hepatoprotective capacity in acetaminophen (APAP)-induced liver disease remains unclear. The aim of
Autor:
Junjun Zhou, Yan Zhao, Ruimin Sun, Jihong Yao, Dongcheng Feng, Rong Fu, Xiaofeng Tian, Zhecheng Wang, Ruiwen Wang, Li Lv
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Alcohol abuse has become common worldwide and has been recognized as a major cause of chronic alcoholic liver disease (ALD). ALD encompasses a complex process that includes a broad scope of hepatic lesions, ranging from steatosis to cirrhosis. In par
Autor:
Tong Li, Xiaofeng Tian, Guo Zu, Anlong Ji, Yang Li, Guangzhi Wang, Dongcheng Feng, Jihong Yao
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Intestinal ischemia reperfusion (I/R) injury is a serious but common pathophysiological process of many diseases, resulting in a high mortality rate in clinical practice. Ubiquitin-specific protease 22 (USP22) acts as regulator of cell cyc
Autor:
Yongfu Zhao, Guangzhi Wang, Zhenlu Li, Xiaofeng Tian, Dongcheng Feng, Jihong Yao, Yang Li, Wasim Qasim
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 4, Pp 1579-1594 (2018)
Background/Aims: Ischemic postconditioning (iPoC) represents a promising strategy to mitigate ischemia/reperfusion (I/R) injury of the intestine, yet the mechanisms of this treatment remain to be elucidated. Circular RNAs (circRNAs), a novel class of
Autor:
Yan Zhao, Musen Lin, Deshun Liu, Yu Sun, Zhao Chen, Ruimin Sun, Jihong Yao, Junjun Zhou, Zhecheng Wang, Li Lv, Xiaofeng Tian
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 11, Pp 1-15 (2020)
Cell Death and Disease, Vol 11, Iss 11, Pp 1-15 (2020)
p66Shc, a master regulator of mitochondrial reactive oxygen species (mtROS), is a crucial mediator of hepatocyte oxidative stress. However, its functional contribution to acetaminophen (APAP)-induced liver injury and the mechanism by which it is modu
Autor:
Yan Zhao, Yu Sun, Huanyu Zhao, Zhecheng Wang, Yunfei Geng, Meiyang Zhu, Ruimin Sun, Jihong Yao, Xiaofeng Tian, Xiaohui Kang, Yue Wang, Yan Hu
Publikováno v:
Toxicology and Applied Pharmacology. 432:115758
Mitochondrial dysfunction is a major factor in nonalcoholic fatty liver disease (NAFLD), preceding insulin resistance and hepatic steatosis. Carnosol (CAR) is a kind of diterpenoid with antioxidant, anti-inflammatory and antitumor activities. Peroxir
Autor:
Yan Zhao, Yan Hu, Zhao Chen, Yang Li, Shili Ning, Jihong Yao, Zhecheng Wang, Deshun Liu, Xiaofeng Tian, Dongcheng Feng
Publikováno v:
Theranostics
Background: Oxidative stress has emerged as an essential factor in the pathogenesis of intestinal ischemia/reperfusion (I/R) injury. The adaptor protein p66Shc is a key regulator of reactive oxygen species (ROS) generation and a mediator of I/R damag
Autor:
Deshun Liu, Yan Zhao, Ruimin Sun, Jihong Yao, Huanyu Zhao, Guangzhi Wang, Zhao Chen, Yang Li, Zhanyu Wang, Xiaofeng Tian, Feng Zhang
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
Background: Hydrogen peroxide (H2O2)-induced mitochondrial oxidative damage is critical to intestinal ischemia/reperfusion (I/R) injury, and PRDX3 is an efficient H2O2 scavenger that protects cells from mitochondrial oxidative damage and apoptosis. H
Autor:
Deshun Liu, Wasim Qasim, Ruimin Sun, Jihong Yao, Zhanyu Wang, Xiaofeng Tian, Yang Li, Dongcheng Feng
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Intestinal ischemia reperfusion (I/R) occurs in various diseases, such as trauma and intestinal transplantation. Excessive reactive oxygen species (ROS) accumulation and subsequent apoptotic cell death in intestinal epithelia are important
Autor:
Zhenlu Li, Xue Shi, Anlong Ji, Chunchun Ding, Dongyan Gao, Yang Li, Junjun Zhou, Jihong Yao, Zhecheng Wang, Dongcheng Feng, Xiaofeng Tian, Yan Zhao
Publikováno v:
Toxicology and Applied Pharmacology. 350:21-31
In recent years, alcoholic liver disease (ALD) has emerged as a growing public health problem worldwide. β-catenin plays an important role in the growth, development, regeneration and metabolic activity of the liver. Salvianolic acid A (SalA) is a w