Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Till, S"'
Autor:
Liesbeth François, Nam Suk Sim, Jasper J. Anink, Iliana Michailidou, James D. Mills, Mark J. Luinenburg, Till S. Zimmer, Peter C. van Rijen, Erwin A. van Vliet, Jeong Ho Lee, Floor E. Jansen, Angelika Mühlebner, Jonathan van Eyll, Diede W. M. Broekaart, Caroline Mijnsbergen, Eleonora Aronica, Stefanie Dedeurwaerdere
Publikováno v:
Neuropathology and Applied Neurobiology
Neuropathology and applied neurobiology, 47(6), 826-839. Wiley-Blackwell
Neuropathology and applied neurobiology
Neuropathology and Applied Neurobiology, 47(6), 826-839. Wiley-Blackwell
Neuropathology and applied neurobiology, 47(6), 826-839. Wiley-Blackwell
Neuropathology and applied neurobiology
Neuropathology and Applied Neurobiology, 47(6), 826-839. Wiley-Blackwell
Aims Focal cortical dysplasia (FCD) type 2 is an epileptogenic malformation of the neocortex associated with somatic mutations in the mammalian target of rapamycin (mTOR) pathway. Histopathologically, FCD 2 is subdivided into FCD 2a and FCD 2b, the o
Autor:
Josef Zamecnik, Anatoly Korotkov, Martha Feucht, Mark J. Luinenburg, Wim Van Hecke, Jeong H Lee, Caroline Mijnsbergen, Lieven Lagae, Till S. Zimmer, Wim G.M. Spliet, Floor E. Jansen, Katarzyna Kotulska, Jackelien van Scheppingen, Paolo Curatolo, Jasper J. Anink, Nam Suk Sim, Angelika Mühlebner, Pavel Krsek, Johannes A. Hainfellner, Sergiusz Jozwiak, Peter C. van Rijen, Erwin A. van Vliet, Diede W. M. Broekaart, David J. Kwiatkowski, Peter B. Crino, Anna Jansen, Eleonora Aronica, Anika Bongaarts, James D. Mills
Publikováno v:
Neuropathology and Applied Neurobiology
Neuropathology and Applied Neurobiology, 47, 796-811. Wiley-Blackwell
Neuropathology and Applied Neurobiology, 47(6), 796-811. Wiley-Blackwell
Neuropathology and applied neurobiology, 47(6), 796-811. Wiley-Blackwell
Neuropathology and Applied Neurobiology, 47, 796-811. Wiley-Blackwell
Neuropathology and Applied Neurobiology, 47(6), 796-811. Wiley-Blackwell
Neuropathology and applied neurobiology, 47(6), 796-811. Wiley-Blackwell
Aims Tuberous sclerosis complex (TSC) is a genetic disorder associated with dysregulation of the mechanistic target of rapamycin complex 1 (mTORC1) signalling pathway. Neurodevelopmental disorders, frequently present in TSC, are linked to cortical tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb0f7241374fa2ea6880a3964dbd171
https://dare.uva.nl/personal/pure/en/publications/microrna34a-activation-in-tuberous-sclerosis-complex-during-early-brain-development-may-lead-to-impaired-corticogenesis(54e41bc9-19fa-4850-90b0-8be834807835).html
https://dare.uva.nl/personal/pure/en/publications/microrna34a-activation-in-tuberous-sclerosis-complex-during-early-brain-development-may-lead-to-impaired-corticogenesis(54e41bc9-19fa-4850-90b0-8be834807835).html
Autor:
James D. Mills, Eleonora Aronica, Wim Van Hecke, Till S. Zimmer, Stefanie Dedeurwaerdere, Johannes C. Baayen, Sander Idema, Nicole N. van der Wel, Anatoly Korotkov, Jonathan van Eyll, Peter C. van Rijen, Rainer Surges, Erwin A. van Vliet, Helmut W. Kessels, Jan A. Gorter, Diede W. M. Broekaart, Angelika Mühlebner, Martin Schidlowski, Theodor Rüber, Bastian David, Gabriele Ruffolo, Liesbeth François
Publikováno v:
Acta Neuropathologica, 142(4), 729-759. Springer Verlag
Acta neuropathologica 142(4), 729-759 (2021). doi:10.1007/s00401-021-02348-6
Acta neuropathologica, 142(4), 729-759. Springer Verlag
Acta Neuropathologica
Acta neuropathologica 142(4), 729-759 (2021). doi:10.1007/s00401-021-02348-6
Acta neuropathologica, 142(4), 729-759. Springer Verlag
Acta Neuropathologica
Neuronal dysfunction due to iron accumulation in conjunction with reactive oxygen species (ROS) could represent an important, yet underappreciated, component of the epileptogenic process. However, to date, alterations in iron metabolism in the epilep
Autor:
Alexander Haese, Christoph Fraune, Thorsten Schlomm, Hartwig Huland, Doris Höflmayer, Guido Sauter, Sarah Minner, Corinna Wittmer, Hans Heinzer, Stefan Steurer, Franziska Büscheck, Katharina Möller, Adam Polonski, Claudia Hube-Magg, Cornelia Schroeder, Markus Graefen, Eike Burandt, Till S. Clauditz, Waldemar Wilczak, Sören Weidemann, David Dum, Ronald Simon
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 29:e29-e38
Tripartite motif containing 24 (TRIM24) is a multifunctional protein involved in p53 degradation, chromatin binding, and transcriptional modulation of nuclear receptors. Emerging research has revealed that upregulation of TRIM24 in numerous tumor typ
Autor:
Hartwig Huland, Sarah Bonk, Alexander Haese, Guido Sauter, Patrick Lebok, Hans Heinzer, Jakob R. Izbicki, Markus Graefen, Andreas Marx, Waldemar Wilczak, Claudia Hube-Magg, Franziska Büscheck, Christian Bernreuther, Till S. Clauditz, Stefan Steurer, Thorsten Schlomm, Ronald Simon, Lena Koopmann, Doris Höflmayer, Till Eichenauer
Publikováno v:
Cancer Biology & Medicine, Vol 18, Iss 1, Pp 245-255 (2021)
Cancer Biology & Medicine
Cancer Biology & Medicine
Objective: Anoctamin 7 (ANO7) is a calcium2+-dependent chloride ion channel protein. Its expression is restricted to prostate epithelial cells. The exact function is unknown. This study aimed to analyze ANO7 expression and its clinical significance i
Autor:
Figen Söylemezoğlu, Martha Feucht, Ingmar Blümcke, Eleonora Aronica, Angelika Mühlebner, Paolo Curatolo, Lieven Lagae, Pavel Krsek, David J. Kwiatkowski, James D. Mills, Victoria-Elisabeth Gruber, Josef Zamecnik, Sergiusz Jozwiak, Roland Coras, Andrew de Neef, Jackelien van Scheppingen, Floor E. Jansen, Till S. Zimmer, Anika Bongaarts, Wim G.M. Spliet, Theresa Scholl, Johannes A. Hainfellner, Anna Jansen, Katarzyna Kotulska
Publikováno v:
Journal of Neuropathology and Experimental Neurology
Journal of neuropathology and experimental neurology, 79(10), 1054-1064. Lippincott Williams and Wilkins
Journal of neuropathology and experimental neurology, 79(10), 1054-1064. Lippincott Williams and Wilkins
Tuberous sclerosis complex (TSC) is a monogenetic disease that arises due to mutations in either the TSC1 or TSC2 gene and affects multiple organ systems. One of the hallmark manifestations of TSC are cortical malformations referred to as cortical tu
Autor:
Hans Heinzer, Sarah Minner, Markus Graefen, Doris Höflmayer, Sebastian Dwertmann Rico, Maria Christina Tsourlakis, Christoph Fraune, Claudia Hube-Magg, Jan Meiners, Christian Bernreuther, Till Eichenauer, Eike Burandt, Stefan Steurer, Ferdous Daghigh, Alexander Haese, Thorsten Schlomm, Katharina Möller, Guido Sauter, Jakob R. Izbicki, Andreas M. Luebke, David Dum, Maximilian Lennartz, Hartwig Huland, Christina Möller-Koop, Ronald Simon, Till S. Clauditz, Corinna Wittmer, Florian Lutz
Publikováno v:
Pathology Oncology Research
Secreted frizzled-related protein 4 (SFRP4) controls WNT signaling and is thought to play a role for tumor aggressiveness. Here, we analyzed a tissue microarray containing 11,152 prostate cancers with pathological, clinical and molecular data by immu
Autor:
Jakob R. Izbicki, Till S. Clauditz, Alexander Haese, Stefan Steurer, Ronald Simon, Thorsten Schlomm, Claudia Hube-Magg, Markus Graefen, Andreas Marx, Hartwig Huland, Guido Sauter, Christian Bernreuther, Aljoscha Schumann, Katharina Möller, Patrick Lebok, Maria Christina Tsourlakis, Elena Bady, Doris Höflmayer, Franziska Büscheck, Adam Polonski, Till Eichenauer, Hans Heinzer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The transcriptional coactivator YAP1 controls the balance between cell proliferation and apoptosis. YAP1 overexpression is linked to poor prognosis in many cancer types, yet its role in prostate cancer is unknown. Here, we applied YAP1 immunohistoche
Autor:
Stefan Steurer, Ronald Simon, Thorsten Schlomm, Anna Lena Wecker, Martina Kluth, Andreas M. Luebke, Doris Höflmayer, Sarah Minner, Hartwig Huland, Christoph Fraune, Hans Heinzer, Sören Weidemann, Andreas Marx, Waldemar Wilczak, Alexander Haese, Till S. Clauditz, Claudia Hube-Magg, Guido Sauter, Katharina Möller, Georgia Makrypidi-Fraune, Sarah Bonk, Christian Bernreuther
Publikováno v:
Virchows Archiv
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) is a ubiquitous RNA splicing factor that is overexpressed and prognostically relevant in various human cancer types. To study the impact of hnRNPA1 expression in prostate cancer, we analyzed a tiss
Autor:
Patrick Lebok, Maria Christina Tsourlakis, Simon Kind, Jan Meiners, Doris Höflmayer, Eike Burandt, Christina Möller-Koop, Hartwig Huland, Till S. Clauditz, Alexander Haese, David Dum, Cosima Göbel, Claudia Hube-Magg, Stefan Steurer, Guido Sauter, Sarah Minner, Jakob R. Izbicki, Ronald Simon, Thorsten Schlomm, Franziska Büscheck, Christoph Fraune, Hans Heinzer, Andreas M. Luebke, Andreas Marx, Markus Graefen
Publikováno v:
Disease Markers, Vol 2020 (2020)
Disease Markers
Disease Markers
Protein phosphatase 1 nuclear-targeting subunit (PNUTS) is ubiquitously expressed and associates with PTEN and protein phosphatase 1 (PP1) to control its activity. The role of PNUTS overexpression has hardly been studied in cancer. In this study, we