Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Stephen Lade"'
Autor:
Peter O’Brien, John F. Seymour, Richard W. Tsang, Anne Capp, Michael MacManus, Mathias Bressel, Andrew Wirth, Stephen Lade, Daniel Roos
Publikováno v:
European Journal of Cancer. 152:129-138
Background This Phase 2 multicentre trial in localised non-gastric marginal zone lymphoma (MZL) evaluated the effectiveness and safety of radiotherapy and documented markers of autoimmunity and Helicobacter pylori infection. Patients and methods Elig
Autor:
Joshy George, Catherine Mitchell, Alex Boussioutas, Jae Ho Cheong, Yu Kuan Huang, Natasha Di Costanzo, Sun Young Rha, Stephen Lade, Rita A. Busuttil, Sharon Pattison, Patrick Tan, Colin M. House
Publikováno v:
Gastric Cancer
Objective Gastric cancer patients generally have a poor outcome, particularly those with advanced-stage disease which is defined by the increased invasion of cancer locally and is associated with higher metastatic potential. This study aimed to ident
Autor:
Belinda A. Campbell, Penny McKelvie, Carrie van der Weyden, Stephen Lade, Odette Buelens, Michelle Sy Goh, Crystal Gao, H. Miles Prince, Christine Khoo, Robert Twigger, Christopher McCormack
Publikováno v:
Journal of the American Academy of Dermatology. 84:185-187
Autor:
David Westerman, Mary Ann Anderson, Mathias Bressel, Mark A. Dawson, Martin Dreyling, Sasanka M. Handunnetti, Juliana Di Iulio, Sarah-Jane Dawson, Rodney J. Hicks, Rishu Agarwal, Christiane Pott, Constantine S. Tam, Kate Burbury, Andrew W. Roberts, Stephen Lade, John F. Seymour, Gillian M. Turner
Publikováno v:
New England Journal of Medicine. 378:1211-1223
Both the BTK inhibitor ibrutinib and the BCL2 inhibitor venetoclax are active as monotherapy in the treatment of mantle-cell lymphoma. Complete response rates of 21% have been observed for each agent when administered as long-term continuous therapy.
Autor:
Michelle Sy Goh, Crystal Gao, Odette Buelens, H. Miles Prince, Christine Khoo, Stephen Lade, Belinda A. Campbell, Simon J. Harrison, Robert Twigger, Christopher McCormack, Carrie van der Weyden
Publikováno v:
Blood. 134(16)
Extracorporeal photopheresis (ECP) has demonstrated therapeutic benefit in patients with Sezary syndrome (SS) and erythrodermic mycosis fungoides (e-MF). To examine the efficacy of ECP in the modern era of novel therapies, we conducted a retrospectiv
Autor:
Toni Maree Rogers, Frank Feleppa, David J Byrne, Rishu Agarwal, David Westerman, Surender Juneja, Danny Liew, Stephen Lade
Publikováno v:
Journal of Clinical Pathology. 69:266-270
Aims MYC rearrangements with or without BCL2 rearrangements have been shown to be associated with poor prognosis and inferior survival in diffuse large B-cell lymphomas (DLBCL). Most of these cases are still diagnosed by fluorescent in situ hybridisa
Autor:
Amit Khot, David Westerman, Constantine S. Tam, Gail Ryan, Christopher McCormack, Robert Twigger, Kate Newland, Stephen Lade, Michael Dickinson, H. Miles Prince, Colin Wood, Odette Buelens, David Ritchie, Charlotte F. M. Hughes
Publikováno v:
Blood. 125:71-81
Numerous systemic treatment options exist for patients with mycosis fungoides (MF) and Sezary syndrome (SS), but no large comparative studies are published. To study the efficacy of treatments, a retrospective analysis of our cutaneous lymphoma datab
Autor:
John F. Seymour, Andrew W. Roberts, Manu Juneja, Stephen Lade, Constantine S. Tam, Surender Juneja, Thomas E Lew, Mary Ann Anderson, Alexandra Gorelik, David C.S. Huang, David Westerman, Meaghan Wall
The BCL2 inhibitor venetoclax achieves responses in ∼79% of patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (RR-CLL/SLL), irrespective of risk factors associated with poor response to chemoimmunotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9905da20445c9da79a62d299a124f0d
https://acuresearchbank.acu.edu.au/item/87744/clinicopathological-features-and-outcomes-of-progression-of-cll-on-the-bcl2-inhibitor-venetoclax
https://acuresearchbank.acu.edu.au/item/87744/clinicopathological-features-and-outcomes-of-progression-of-cll-on-the-bcl2-inhibitor-venetoclax
Autor:
Alex Boussioutas, Kylie Ioculano, Catherine Mitchell, Patrick Tan, Rita A. Busuttil, Izhak Haviv, Richard W. Tothill, Joshy George, Stephen Lade, A. Kowalczyk
Publikováno v:
Clinical Cancer Research. 20:2761-2772
Purpose: Gene-expression profiling has revolutionized the way we think about cancer and confers the ability to observe the synchronous expression of thousands of genes. The use of putative genome-level expression profiles has allowed biologists to ob
Autor:
William D. Figg, Elaine S. Jaffe, Stephen Lade, Craig B. Reeder, John P. Leonard, John Wright, Maria L. Turner, Erin R. Gardner, A. Tito Fojo, Larisa J. Geskin, Robin Frye, H. Miles Prince, Maryalice Stetler-Stevenson, Mark Kirschbaum, Richard Piekarz, Steven L. Allen, Jasmine Zain, Susan E. Bates, David Joske, Seth M. Steinberg
Publikováno v:
Journal of Clinical Oncology. 27:5410-5417
Purpose Romidepsin (depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the histone deacetylase inhibitors. On the basis of observed responses in a phase I trial, a phase II trial of romidepsin in pat