Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Owen, J"'
Autor:
Evans, RA, Leavy, OC, Richardson, M, Elneima, O, McCauley, HJC, Shikotra, A, Singapuri, A, Sereno, M, Saunders, RM, Harris, VC, Houchen-Wolloff, L, Aul, R, Beirne, P, Bolton, CE, Brown, JS, Choudhury, G, Diar-Bakerly, N, Easom, N, Echevarria, C, Fuld, J, Hart, N, Hurst, J, Jones, MG, Parekh, D, Pfeffer, P, Rahman, NM, Rowland-Jones, SL, Shah, AM, Wootton, DG, Chalder, T, Davies, MJ, De Soyza, A, Geddes, JR, Greenhalf, W, Greening, NJ, Heaney, LG, Heller, S, Howard, LS, Jacob, J, Jenkins, RG, Lord, JM, Man, WD-C, McCann, GP, Neubauer, S, Openshaw, PJM, Porter, JC, Rowland, MJ, Scott, JT, Semple, MG, Singh, SJ, Thomas, DC, Toshner, M, Lewis, KE, Thwaites, RS, Briggs, A, Docherty, AB, Kerr, S, Lone, NI, Quint, J, Sheikh, A, Thorpe, M, Zheng, B, Chalmers, JD, Ho, LP, Horsley, A, Marks, M, Poinasamy, K, Raman, B, Harrison, EM, Wain, LV, Brightling, CE, Abel, K, Adamali, H, Adeloye, D, Adeyemi, O, Adrego, R, Jimenez, LAA, Ahmad, S, Haider, NA, Ahmed, R, Ahwireng, N, Ainsworth, M, Al-Sheklly, B, Alamoudi, A, Ali, M, Aljaroof, M, All, AM, Allan, L, Allen, RJ, Allerton, L, Allsop, L, Almeida, P, Altmann, D, Corral, MA, Amoils, S, Anderson, D, Antoniades, C, Arbane, G, Arias, A, Armour, C, Armstrong, L, Armstrong, N, Arnold, D, Arnold, H, Ashish, A, Ashworth, A, Ashworth, M, Aslani, S, Assefa-Kebede, H, Atkin, C, Atkin, P, Aung, H, Austin, L, Avram, C, Ayoub, A, Babores, M, Baggott, R, Bagshaw, J, Baguley, D, Bailey, L, Baillie, JK, Bain, S, Bakali, M, Bakau, M, Baldry, E, Baldwin, D, Ballard, C, Banerjee, A, Bang, B, Barker, RE, Barman, L, Barratt, S, Barrett, F, Basire, D, Basu, N, Bates, M, Bates, A, Batterham, R, Baxendale, H, Bayes, H, Beadsworth, M, Beckett, P, Beggs, M, Begum, M, Bell, D, Bell, R, Bennett, K, Beranova, E, Bermperi, A, Berridge, A, Berry, C, Betts, S, Bevan, E, Bhui, K, Bingham, M, Birchall, K, Bishop, L, Bisnauthsing, K, Blaikely, J, Bloss, A, Bolger, A, Bonnington, J, Botkai, A, Bourne, C, Bourne, M, Bramham, K, Brear, L, Breen, G, Breeze, J, Bright, E, Brill, S, Brindle, K, Broad, L, Broadley, A, Brookes, C, Broome, M, Brown, A, Brown, J, Brown, M, Brown, V, Brown, CW, Brugha, T, Brunskill, N, Buch, M, Buckley, P, Bularga, A, Bullmore, E, Burden, L, Burdett, T, Burn, D, Burns, G, Burns, A, Busby, J, Butcher, R, Butt, A, Byrne, S, Cairns, P, Calder, PC, Calvelo, E, Carborn, H, Card, B, Carr, C, Carr, L, Carson, G, Carter, P, Casey, A, Cassar, M, Cavanagh, J, Chablani, M, Chambers, RC, Chan, F, Channon, KM, Chapman, K, Charalambou, A, Chaudhuri, N, Checkley, A, Chen, J, Cheng, Y, Chetham, L, Childs, C, Chilvers, ER, Chinoy, H, Chiribiri, A, Chong-James, K, Choudhury, N, Chowienczyk, P, Christie, C, Chrystal, M, Clark, D, Clark, C, Clarke, J, Clohisey, S, Coakley, G, Coburn, Z, Coetzee, S, Cole, J, Coleman, C, Conneh, F, Connell, D, Connolly, B, Connor, L, Cook, A, Cooper, B, Cooper, J, Cooper, S, Copeland, D, Cosier, T, Coulding, M, Coupland, C, Cox, E, Craig, T, Crisp, P, Cristiano, D, Crooks, MG, Cross, A, Cruz, I, Cullinan, P, Cuthbertson, D, Daines, L, Dalton, M, Daly, P, Daniels, A, Dark, P, Dasgin, J, David, A, David, C, Davies, E, Davies, F, Davies, G, Davies, GA, Davies, K, Dawson, J, Daynes, E, Deakin, B, Deans, A, Deas, C, Deery, J, Defres, S, Dell, A, Dempsey, K, Denneny, E, Dennis, J, Dewar, A, Dharmagunawardena, R, Dickens, C, Dipper, A, Diver, S, Diwanji, SN, Dixon, M, Djukanovic, R, Dobson, H, Dobson, SL, Donaldson, A, Dong, T, Dormand, N, Dougherty, A, Dowling, R, Drain, S, Draxlbauer, K, Drury, K, Dulawan, P, Dunleavy, A, Dunn, S, Earley, J, Edwards, S, Edwardson, C, El-Taweel, H, Elliott, A, Elliott, K, Ellis, Y, Elmer, A, Evans, D, Evans, H, Evans, J, Evans, R, Evans, RI, Evans, T, Evenden, C, Evison, L, Fabbri, L, Fairbairn, S, Fairman, A, Fallon, K, Faluyi, D, Favager, C, Fayzan, T, Featherstone, J, Felton, T, Finch, J, Finney, S, Finnigan, J, Finnigan, L, Fisher, H, Fletcher, S, Flockton, R, Flynn, M, Foot, H, Foote, D, Ford, A, Forton, D, Fraile, E, Francis, C, Francis, R, Francis, S, Frankel, A, Fraser, E, Free, R, French, N, Fu, X, Furniss, J, Garner, L, Gautam, N, George, J, George, P, Gibbons, M, Gill, M, Gilmour, L, Gleeson, F, Glossop, J, Glover, S, Goodman, N, Goodwin, C, Gooptu, B, Gordon, H, Gorsuch, T, Greatorex, M, Greenhaff, PL, Greenhalgh, A, Greenwood, J, Gregory, H, Gregory, R, Grieve, D, Griffin, D, Griffiths, L, Guerdette, A-M, Guio, BG, Gummadi, M, Gupta, A, Gurram, S, Guthrie, E, Guy, Z, Henson, HH, Hadley, K, Haggar, A, Hainey, K, Hairsine, B, Haldar, P, Hall, I, Hall, L, Halling-Brown, M, Hamil, R, Hancock, A, Hancock, K, Hanley, NA, Haq, S, Hardwick, HE, Hardy, E, Hardy, T, Hargadon, B, Harrington, K, Harris, E, Harrison, P, Harvey, A, Harvey, M, Harvie, M, Haslam, L, Havinden-Williams, M, Hawkes, J, Hawkings, N, Haworth, J, Hayday, A, Haynes, M, Hazeldine, J, Hazelton, T, Heeley, C, Heeney, JL, Heightman, M, Henderson, M, Hesselden, L, Hewitt, M, Highett, V, Hillman, T, Hiwot, T, Hoare, A, Hoare, M, Hockridge, J, Hogarth, P, Holbourn, A, Holden, S, Holdsworth, L, Holgate, D, Holland, M, Holloway, L, Holmes, K, Holmes, M, Holroyd-Hind, B, Holt, L, Hormis, A, Hosseini, A, Hotopf, M, Howard, K, Howell, A, Hufton, E, Hughes, AD, Hughes, J, Hughes, R, Humphries, A, Huneke, N, Hurditch, E, Husain, M, Hussell, T, Hutchinson, J, Ibrahim, W, Ilyas, F, Ingham, J, Ingram, L, Ionita, D, Isaacs, K, Ismail, K, Jackson, T, James, WY, Jarman, C, Jarrold, I, Jarvis, H, Jastrub, R, Jayaraman, B, Jezzard, P, Jiwa, K, Johnson, C, Johnson, S, Johnston, D, Jolley, CJ, Jones, D, Jones, G, Jones, H, Jones, I, Jones, L, Jones, S, Jose, S, Kabir, T, Kaltsakas, G, Kamwa, V, Kanellakis, N, Kaprowska, S, Kausar, Z, Keenan, N, Kelly, S, Kemp, G, Kerslake, H, Key, AL, Khan, F, Khunti, K, Kilroy, S, King, B, King, C, Kingham, L, Kirk, J, Kitterick, P, Klenerman, P, Knibbs, L, Knight, S, Knighton, A, Kon, O, Kon, S, Kon, SS, Koprowska, S, Korszun, A, Koychev, I, Kurasz, C, Kurupati, P, Laing, C, Lamlum, H, Landers, G, Langenberg, C, Lasserson, D, Lavelle-Langham, L, Lawrie, A, Lawson, C, Layton, A, Lea, A, Lee, D, Lee, J-H, Lee, E, Leitch, K, Lenagh, R, Lewis, D, Lewis, J, Lewis, V, Lewis-Burke, N, Li, X, Light, T, Lightstone, L, Lilaonitkul, W, Lim, L, Linford, S, Lingford-Hughes, A, Lipman, M, Liyanage, K, Lloyd, A, Logan, S, Lomas, D, Loosley, R, Lota, H, Lovegrove, W, Lucey, A, Lukaschuk, E, Lye, A, Lynch, C, MacDonald, S, MacGowan, G, Macharia, I, Mackie, J, Macliver, L, Madathil, S, Madzamba, G, Magee, N, Magtoto, MM, Mairs, N, Majeed, N, Major, E, Malein, F, Malim, M, Mallison, G, Mandal, S, Mangion, K, Manisty, C, Manley, R, March, K, Marciniak, S, Marino, P, Mariveles, M, Marouzet, E, Marsh, S, Marshall, B, Marshall, M, Martin, J, Martineau, A, Martinez, LM, Maskell, N, Matila, D, Matimba-Mupaya, W, Matthews, L, Mbuyisa, A, McAdoo, S, McCall, JW, McAllister-Williams, H, McArdle, A, McArdle, P, McAulay, D, McCormick, J, McCormick, W, McCourt, P, McGarvey, L, McGee, C, Mcgee, K, McGinness, J, McGlynn, K, McGovern, A, McGuinness, H, McInnes, IB, McIntosh, J, McIvor, E, McIvor, K, McLeavey, L, McMahon, A, McMahon, MJ, McMorrow, L, Mcnally, T, McNarry, M, McNeill, J, McQueen, A, McShane, H, Mears, C, Megson, C, Megson, S, Mehta, P, Meiring, J, Melling, L, Mencias, M, Menzies, D, Morillas, MM, Michael, A, Milligan, L, Miller, C, Mills, C, Mills, NL, Milner, L, Misra, S, Mitchell, J, Mohamed, A, Mohamed, N, Mohammed, S, Molyneaux, PL, Monteiro, W, Moriera, S, Morley, A, Morrison, L, Morriss, R, Morrow, A, Moss, AJ, Moss, P, Motohashi, K, Msimanga, N, Mukaetova-Ladinska, E, Munawar, U, Murira, J, Nanda, U, Nassa, H, Nasseri, M, Neal, A, Needham, R, Neill, P, Newell, H, Newman, T, Newton-Cox, A, Nicholson, T, Nicoll, D, Nolan, CM, Noonan, MJ, Norman, C, Novotny, P, Nunag, J, Nwafor, L, Nwanguma, U, Nyaboko, J, O'Donnell, K, O'Brien, C, O'Brien, L, O'Regan, D, Odell, N, Ogg, G, Olaosebikan, O, Oliver, C, Omar, Z, Orriss-Dib, L, Osborne, L, Osbourne, R, Ostermann, M, Overton, C, Owen, J, Oxton, J, Pack, J, Pacpaco, E, Paddick, S, Painter, S, Pakzad, A, Palmer, S, Papineni, P, Paques, K, Paradowski, K, Pareek, M, Parfrey, H, Pariante, C, Parker, S, Parkes, M, Parmar, J, Patale, S, Patel, B, Patel, M, Patel, S, Pattenadk, D, Pavlides, M, Payne, S, Pearce, L, Pearl, JE, Peckham, D, Pendlebury, J, Peng, Y, Pennington, C, Peralta, I, Perkins, E, Peterkin, Z, Peto, T, Petousi, N, Petrie, J, Phipps, J, Pimm, J, Hanley, KP, Pius, R, Plant, H, Plein, S, Plekhanova, T, Plowright, M, Polgar, O, Poll, L, Porter, J, Portukhay, S, Powell, N, Prabhu, A, Pratt, J, Price, A, Price, C, Price, D, Price, L, Prickett, A, Propescu, J, Pugmire, S, Quaid, S, Quigley, J, Qureshi, H, Qureshi, IN, Radhakrishnan, K, Ralser, M, Ramos, A, Ramos, H, Rangeley, J, Rangelov, B, Ratcliffe, L, Ravencroft, P, Reddington, A, Reddy, R, Redfearn, H, Redwood, D, Reed, A, Rees, M, Rees, T, Regan, K, Reynolds, W, Ribeiro, C, Richards, A, Richardson, E, Rivera-Ortega, P, Roberts, K, Robertson, E, Robinson, E, Robinson, L, Roche, L, Roddis, C, Rodger, J, Ross, A, Ross, G, Rossdale, J, Rostron, A, Rowe, A, Rowland, A, Rowland, J, Roy, K, Roy, M, Rudan, I, Russell, R, Russell, E, Saalmink, G, Sabit, R, Sage, EK, Samakomva, T, Samani, N, Sampson, C, Samuel, K, Samuel, R, Sanderson, A, Sapey, E, Saralaya, D, Sargant, J, Sarginson, C, Sass, T, Sattar, N, Saunders, K, Saunders, P, Saunders, LC, Savill, H, Saxon, W, Sayer, A, Schronce, J, Schwaeble, W, Scott, K, Selby, N, Sewell, TA, Shah, K, Shah, P, Shankar-Hari, M, Sharma, M, Sharpe, C, Sharpe, M, Shashaa, S, Shaw, A, Shaw, K, Shaw, V, Shelton, S, Shenton, L, Shevket, K, Short, J, Siddique, S, Siddiqui, S, Sidebottom, J, Sigfrid, L, Simons, G, Simpson, J, Simpson, N, Singh, C, Singh, S, Sissons, D, Skeemer, J, Slack, K, Smith, A, Smith, D, Smith, S, Smith, J, Smith, L, Soares, M, Solano, TS, Solly, R, Solstice, AR, Soulsby, T, Southern, D, Sowter, D, Spears, M, Spencer, LG, Speranza, F, Stadon, L, Stanel, S, Steele, N, Steiner, M, Stensel, D, Stephens, G, Stephenson, L, Stern, M, Stewart, I, Stimpson, R, Stockdale, S, Stockley, J, Stoker, W, Stone, R, Storrar, W, Storrie, A, Storton, K, Stringer, E, Strong-Sheldrake, S, Stroud, N, Subbe, C, Sudlow, CL, Suleiman, Z, Summers, C, Summersgill, C, Sutherland, D, Sykes, DL, Sykes, R, Talbot, N, Tan, AL, Tarusan, L, Tavoukjian, V, Taylor, A, Taylor, C, Taylor, J, Te, A, Tedd, H, Tee, CJ, Teixeira, J, Tench, H, Terry, S, Thackray-Nocera, S, Thaivalappil, F, Thamu, B, Thickett, D, Thomas, C, Thomas, S, Thomas, AK, Thomas-Woods, T, Thompson, T, Thompson, AAR, Thornton, T, Tilley, J, Tinker, N, Tiongson, GF, Tobin, M, Tomlinson, J, Tong, C, Touyz, R, Tripp, KA, Tunnicliffe, E, Turnbull, A, Turner, E, Turner, S, Turner, V, Turner, K, Turney, S, Turtle, L, Turton, H, Ugoji, J, Ugwuoke, R, Upthegrove, R, Valabhji, J, Ventura, M, Vere, J, Vickers, C, Vinson, B, Wade, E, Wade, P, Wainwright, T, Wajero, LO, Walder, S, Walker, S, Wall, E, Wallis, T, Walmsley, S, Walsh, JA, Walsh, S, Warburton, L, Ward, TJC, Warwick, K, Wassall, H, Waterson, S, Watson, E, Watson, L, Watson, J, Welch, C, Welch, H, Welsh, B, Wessely, S, West, S, Weston, H, Wheeler, H, White, S, Whitehead, V, Whitney, J, Whittaker, S, Whittam, B, Whitworth, V, Wight, A, Wild, J, Wilkins, M, Wilkinson, D, Williams, N, Williams, J, Williams-Howard, SA, Willicombe, M, Willis, G, Willoughby, J, Wilson, A, Wilson, D, Wilson, I, Window, N, Witham, M, Wolf-Roberts, R, Wood, C, Woodhead, F, Woods, J, Wormleighton, J, Worsley, J, Wraith, D, Wright, C, Wright, L, Wright, S, Wyles, J, Wynter, I, Xu, M, Yasmin, N, Yasmin, S, Yates, T, Yip, KP, Young, B, Young, S, Young, A, Yousuf, AJ, Zawia, A, Zeidan, L, Zhao, B, Zongo, O
Publikováno v:
The PHOSP-COVID Collaborative Group, Evans, R A, Richardson, M, Brown, J S, Hart, N, Jones, M G, Rahman, N M, Shah, A M, Davies, M J, Geddes, J R, Heaney, L G, Jenkins, R G, McCann, G P, Porter, J C, Rowland, M J, Scott, J T, Semple, M G, Singh, S J, Kerr, S, Ahmad, S, Ali, M, Armour, C, Baillie, J K, Banerjee, A, Barker, R E, Begum, M, Bell, D, Bell, R, Bennett, K, Bingham, M, Bourne, M, Brown, A, Brown, J S, Brown, M, Brown, V, Burns, G, Burns, A, Busby, J, Butt, A, Byrne, S, Cairns, P, Carr, C, Carson, G, Casey, A, Chambers, R C, Chapman, K, Chen, J, Cheng, Y, Clarke, J, Cole, J, Connolly, B, Cooper, B, Cooper, J, Cooper, S, Craig, T, Cross, A, Daly, P, Davies, G, Davies, G, Dobson, S L, Drain, S, Edwards, S, Elliott, A, Elliott, K, Evans, D, Evans, J, Evans, R A, Evans, R A, Fletcher, S, Flynn, M, Ford, A, Francis, S, Fu, X, George, J, Glover, S, Goodwin, C, Greenwood, J, Grieve, D, Griffin, D, Gupta, A, Hall, L, Hanley, N A, Harrington, K, Harris, E, Harvey, A, Harvey, M, Hewitt, M, Holloway, L, Howard, K, Hughes, A D, Hughes, J, Hughes, R, Hutchinson, J, Johnson, C, Johnson, S, Johnston, D, Jones, D, Jones, H, Jones, L, Jones, S, Kelly, S, Khan, F, Kilroy, S, King, B, Kirk, J, Lee, J H, Lewis, J, Li, X, Lynch, C, Magee, N, Marshall, B, Marshall, M, Martin, J, Matthews, L, McArdle, A, McCormick, J, McCormick, W, McCourt, P, McGarvey, L, McInnes, I B, McIntosh, J, McIvor, K, McMahon, A, McMahon, M J, Mcnally, T, McNeill, J, Miller, C, Mills, C, Milner, L, Mitchell, J, Mohamed, A, Mohammed, S, Morrison, L, Newman, T, Nolan, C M, O'Donnell, K, O'Brien, C, O'Brien, L, Owen, J, Palmer, S, Pavlides, M, Peng, Y, Peto, T, Porter, J C, Powell, N, Pratt, J, Price, A, Price, D, Price, L, Reed, A, Robertson, E, Robinson, E, Robinson, L, Ross, A, Ross, G, Roy, M, Russell, E, Scott, K, Sewell, T A, Sharma, M, Shaw, A, Siddiqui, S, Simpson, J, Simpson, N, Singh, S J, Smith, A, Smith, D, Smith, S, Smith, J, Smith, L, Stewart, I, Taylor, A, Taylor, C, Taylor, J, Thomas, C, Thomas, S, Thompson, T, Thompson, A A R, Turner, S, Walker, S, Walsh, J A, Walsh, S, Ward, T J C, Watson, E, Watson, L, Watson, J, White, S, Wilkinson, D, Williams, J, Wilson, A, Wilson, D, Wilson, I, Woods, J, Wright, C, Wright, L, Wright, S, Xu, M, Young, S & Young, A 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study ', The Lancet Respiratory Medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Group, PHOSP-COVID C & Dark, P 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. ', The Lancet. Respiratory medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/s2213-2600(22)00127-8
Chalder, T 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK : a prospective observational study ', The lancet. Respiratory medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Docherty, A B, Kerr, S, Lone, N I, Sheikh, A, Zheng, B & Harrison, E M & Baillie, J K 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK : a prospective observational study ', The Lancet Respiratory Medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Group, PHOSP-COVID C & Dark, P 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. ', The Lancet. Respiratory medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/s2213-2600(22)00127-8
Chalder, T 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK : a prospective observational study ', The lancet. Respiratory medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Docherty, A B, Kerr, S, Lone, N I, Sheikh, A, Zheng, B & Harrison, E M & Baillie, J K 2022, ' Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK : a prospective observational study ', The Lancet Respiratory Medicine, vol. 10, no. 8, pp. 761-775 . https://doi.org/10.1016/S2213-2600(22)00127-8
Background No effective pharmacological or non-pharmacological interventions exist for patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for COVID-19, identify factors associated with patient-perceived recovery,
Autor:
Riwa Meshaka, Fern C. Whittam, Myriam Guessoum, Saigeet Eleti, Susan C. Shelmerdine, Owen J. Arthurs, Kieran McHugh, Melanie P. Hiorns, Paul D. Humphries, Alistair D. Calder, Marina J. Easty, Edward P. Gaynor, Tom Watson
Publikováno v:
Radiology. 303:173-181
Background Children with pediatric inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as multisystem inflammatory syndrome in children, present with abdominal pain among other nonspecific symptoms. Although initial imag
Autor:
Stéphanie E. Reitsma, Hari Hara Sudhan Lakshmanan, Jennifer Johnson, Jiaqing Pang, Iván Parra-Izquierdo, Alex R. Melrose, Jaewoo Choi, Deirdre E. J. Anderson, Monica T. Hinds, Jan Frederik Stevens, Joseph E. Aslan, Owen J. T. McCarty, Jamie O. Lo
Publikováno v:
Am J Physiol Cell Physiol
Cannabis usage has steadily increased as acceptance is growing for both medical and recreational reasons. Medical cannabis is administered for treatment of chronic pain based on the premise that the endocannabinoid system signals desensitize pain sen
Autor:
Carrie E. Lyons, Owen J. Stokes-Cawley, Anna Simkin, Anna L. Bowring, Iliassou Mfochive Njindam, Oudou Njoya, Anne Zoung-Kanyi Bissek, Ubald Tamoufe, Sandra Georges, Florence Zeh Kakanou, Gnilane Turpin, Daniel Levitt, Serge Clotaire Billong, Sharmistha Mishra, Stefan Baral
Publikováno v:
BMC Infectious Diseases. 22
Background Men who have sex with men (MSM) are consistently burdened by HIV at higher levels than other adults. While HIV prevention programs for MSM are growing in coverage and quality, HIV incidence remains high. In response, pre-exposure prophylax
Autor:
Peter Melville, Farheena Mohammed, Chris RuiWen Kuo, Jack Bradley, Gavin Preston, Owen J Dempsey
Publikováno v:
The journal of the Royal College of Physicians of Edinburgh. 52(1)
We describe the case of a 70-year-old never smoker with chronic lymphocytic leukaemia, treated with single agent ibrutinib therapy. Chest imaging noted nodular change and mediastinal lymphadenopathy, which showed avid uptake on positron emission tomo
Autor:
John RP Knight, Nikola Vlahov, David M Gay, Rachel A Ridgway, William James Faller, Christopher Proud, Giovanna R Mallucci, Tobias von der Haar, Christopher Mark Smales, Anne E Willis, Owen J Sansom
Publikováno v:
eLife, Vol 10 (2021)
Knight, J R P, Vlahov, N, Gay, D M, Ridgway, R A, Faller, W J, Proud, C, Mallucci, G R, von der Haar, T, Smales, C M, Willis, A E & Sansom, O J 2021, ' Rpl24 Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K ', eLife, vol. 10, e69729 . https://doi.org/10.7554/eLife.69729
eLife
Knight, J R P, Vlahov, N, Gay, D M, Ridgway, R A, Faller, W J, Proud, C, Mallucci, G R, von der Haar, T, Smales, C M, Willis, A E & Sansom, O J 2021, ' Rpl24 Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K ', eLife, vol. 10, e69729 . https://doi.org/10.7554/eLife.69729
eLife
Increased protein synthesis supports the rapid cell proliferation associated with cancer. The Rpl24Bst mutant mouse reduces the expression of the ribosomal protein RPL24 and has been used to suppress translation and limit tumorigenesis in multiple mo
Autor:
Rachana Patel, Catriona A. Ford, Lisa Rodgers, Linda K. Rushworth, Janis Fleming, Ernest Mui, Tong Zhang, David Watson, Victoria Lynch, Gillian Mackay, David Sumpton, Owen J. Sansom, Johan Vande Voorde, Hing Y. Leung
Prostate cancer is the second most common cause of cancer mortality in men worldwide. Applying a novel genetically engineered mouse model (GEMM) of aggressive prostate cancer driven by deficiency of the tumor suppressors PTEN and Sprouty2 (SPRY2), we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7e042122ac25952e9878edb2dd1c94
https://eprints.gla.ac.uk/273869/1/273869.pdf
https://eprints.gla.ac.uk/273869/1/273869.pdf
Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function
Autor:
Tony J. Zheng, Elizabeth R Lofurno, Joseph J. Shatzel, Joseph E. Aslan, Alexander R. Melrose, Monica T. Hinds, Tia C L Kohs, Hari Hara Sudhan Lakshmanan, Kevin G. Phillips, Owen J. T. McCarty, Jiaqing Pang, Meghan E. Fallon, Anh T. P. Ngo
Publikováno v:
Am J Physiol Cell Physiol
Spleen tyrosine kinase (Syk) and Bruton’s tyrosine kinase (BTK) play critical roles in platelet physiology, facilitating intracellular immunoreceptor tyrosine-based activation motif (ITAM)-mediated signaling downstream of platelet glycoprotein VI (
Autor:
Joseph J. Shatzel, Andras Gruber, Cristina Puy, Christina U. Lorentz, Vikram Raghunathan, Jiaqing Pang, David Gailani, Owen J. T. McCarty, Stéphanie E. Reitsma, Erik I. Tucker
Publikováno v:
Am J Physiol Cell Physiol
Factor XI (FXI) has been shown to bind platelets, but the functional significance of this observation remains unknown. Platelets are essential for hemostasis and play a critical role in thrombosis, whereas FXI is not essential for hemostasis but prom
Autor:
Imran Ahmad, Laura C. A. Galbraith, Gillian M. Mackay, Ernest Mui, Colin Nixon, Owen J. Sansom, Hing Y. Leung, David Sumpton, Ann Hedley, David P. Strachan
Publikováno v:
Oncogene
Peroxisome Proliferator-Activated Receptor Gamma (PPARG) is one of the three members of the PPAR family of transcription factors. Besides its roles in adipocyte differentiation and lipid metabolism, we recently demonstrated an association between PPA