Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Medha Priyadarshini"'
Autor:
Kristen R. Lednovich, Chioma Nnyamah, Sophie Gough, Medha Priyadarshini, Kai Xu, Barton Wicksteed, Sidharth Mishra, Shalini Jain, Joseph L. Zapater, Hariom Yadav, Brian T. Layden
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 323(3)
Free fatty acid receptor 3 (FFA3) is a recently-deorphanized G-protein-coupled receptor. Its ligands are short-chain fatty acids (SCFAs), which are key nutrients derived from the gut microbiome fermentation process that play diverse roles in the regu
Autor:
Brian T. Layden, Congcong He, Anton E. Ludvik, Gautham Oroskar, Medha Priyadarshini, Connor Cole, Barton Wicksteed
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
The free fatty acid receptor 3 (FFA3) is a nutrient sensor of gut microbiota-generated nutrients, the short-chain fatty acids. Previously, we have shown that FFA3 is expressed in β-cells and inhibits islet insulin secretion ex vivo. Here, we determi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:678-687
Hexokinase domain containing 1, a recently discovered putative fifth hexokinase, is hypothesized to play key roles in glucose metabolism. Specifically, during pregnancy in a recent genome wide association study (GWAS), a strong correlation between HK
Autor:
Sirimon Reutrakul, Ben S. Gerber, Jade J. Yeh, Jason C Park, Kirstie K. Danielson, J. Jason McAnany, Stephanie J. Crowley, Medha Priyadarshini, Felix Y. Chau, Tracy Baynard, Erin C. Hanlon
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Background: Intrinsically photosensitive retinal ganglion cells (ipRGCs) control non-visual light responses (e.g. pupillary light reflex and circadian entrainment). Patients with diabetic retinopathy (DR) show reduced ipRGC function, as inferred by a
Autor:
William L. Lowe, Brian T. Layden, Anthony R. Angueira, Medha Priyadarshini, Timothy E. Reddy, Xianzhong Ding, Guang Yu Yang, Amy C. Y. Lo, Cong Guo, Korri S. Hershenhouse, Anton E. Ludvik, Carolina M. Pusec
Publikováno v:
Endocrinology. 157:3452-3461
In a recent genome-wide association study, hexokinase domain-containing protein 1, or HKDC1, was found to be associated with gestational glucose levels during 2-hour glucose tolerance tests at 28 weeks of pregnancy. Because our understanding of the m
Autor:
Brian T. Layden, Medha Priyadarshini
Publikováno v:
Islets. 7(2)
The short chain fatty acid (SCFA) receptor (free fatty acid receptor-3; FFAR3) is expressed in pancreatic β cells; however, its role in insulin secretion is not clearly defined. Here, we examined the role of FFAR3 in insulin secretion. Using islets
Autor:
Shubha Priyamvada, Medha Priyadarshini, N.A. Arivarasu, Neelam Farooq, Sheeba Khan, Sara A. Khan, Md. Wasim Khan, A.N.K. Yusufi
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 78(6)
Gentamicin (GM)-induced nephrotoxicity limits its long-term clinical use. Several agents/strategies were attempted to prevent GM nephrotoxicity but were not found suitable for clinical practice. Dietary fish oil (FO) retard the progression of certain