Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Martina Müller-Nurasyid"'
Autor:
Aenne S. von Falkenhausen, Rebecca Freudling, Melanie Waldenberger, Christian Gieger, Annette Peters, Martina Müller-Nurasyid, Stefan Kääb, Moritz F. Sinner
Publikováno v:
Aging 14, 5620-5627 (2022)
AIMS: Aging is accompanied by telomere shortening. Increased telomere shortening is considered a marker of premature aging. Cardiac aging results in the development of cardiac pathologies. Electrocardiogram (ECG) measures reflect cardiac excitation,
Autor:
William J. Young, Najim Lahrouchi, Aaron Isaacs, ThuyVy Duong, Luisa Foco, Farah Ahmed, Jennifer A. Brody, Reem Salman, Raymond Noordam, Jan-Walter Benjamins, Jeffrey Haessler, Leo-Pekka Lyytikäinen, Linda Repetto, Maria Pina Concas, Marten E. van den Berg, Stefan Weiss, Antoine R. Baldassari, Traci M. Bartz, James P. Cook, Daniel S. Evans, Rebecca Freudling, Oliver Hines, Jonas L. Isaksen, Honghuang Lin, Hao Mei, Arden Moscati, Martina Müller-Nurasyid, Casia Nursyifa, Yong Qian, Anne Richmond, Carolina Roselli, Kathleen A. Ryan, Eduardo Tarazona-Santos, Sébastien Thériault, Stefan van Duijvenboden, Helen R. Warren, Jie Yao, Dania Raza, Stefanie Aeschbacher, Gustav Ahlberg, Alvaro Alonso, Laura Andreasen, Joshua C. Bis, Eric Boerwinkle, Archie Campbell, Eulalia Catamo, Massimiliano Cocca, Michael J. Cutler, Dawood Darbar, Alessandro De Grandi, Antonio De Luca, Jun Ding, Christina Ellervik, Patrick T. Ellinor, Stephan B. Felix, Philippe Froguel, Christian Fuchsberger, Martin Gögele, Claus Graff, Mariaelisa Graff, Xiuqing Guo, Torben Hansen, Susan R. Heckbert, Paul L. Huang, Heikki V. Huikuri, Nina Hutri-Kähönen, M. Arfan Ikram, Rebecca D. Jackson, Juhani Junttila, Maryam Kavousi, Jan A. Kors, Thiago P. Leal, Rozenn N. Lemaitre, Henry J. Lin, Lars Lind, Allan Linneberg, Simin Liu, Peter W. MacFarlane, Massimo Mangino, Thomas Meitinger, Massimo Mezzavilla, Pashupati P. Mishra, Rebecca N. Mitchell, Nina Mononen, May E. Montasser, Alanna C. Morrison, Matthias Nauck, Victor Nauffal, Pau Navarro, Kjell Nikus, Guillaume Pare, Kristen K. Patton, Giulia Pelliccione, Alan Pittman, David J. Porteous, Peter P. Pramstaller, Michael H. Preuss, Olli T. Raitakari, Alexander P. Reiner, Antonio Luiz P. Ribeiro, Kenneth M. Rice, Lorenz Risch, David Schlessinger, Ulrich Schotten, Claudia Schurmann, Xia Shen, M. Benjamin Shoemaker, Gianfranco Sinagra, Moritz F. Sinner, Elsayed Z. Soliman, Monika Stoll, Konstantin Strauch, Kirill Tarasov, Kent D. Taylor, Andrew Tinker, Stella Trompet, André Uitterlinden, Uwe Völker, Henry Völzke, Melanie Waldenberger, Lu-Chen Weng, Eric A. Whitsel, James G. Wilson, Christy L. Avery, David Conen, Adolfo Correa, Francesco Cucca, Marcus Dörr, Sina A. Gharib, Giorgia Girotto, Niels Grarup, Caroline Hayward, Yalda Jamshidi, Marjo-Riitta Järvelin, J. Wouter Jukema, Stefan Kääb, Mika Kähönen, Jørgen K. Kanters, Charles Kooperberg, Terho Lehtimäki, Maria Fernanda Lima-Costa, Yongmei Liu, Ruth J. F. Loos, Steven A. Lubitz, Dennis O. Mook-Kanamori, Andrew P. Morris, Jeffrey R. O’Connell, Morten Salling Olesen, Michele Orini, Sandosh Padmanabhan, Cristian Pattaro, Annette Peters, Bruce M. Psaty, Jerome I. Rotter, Bruno Stricker, Pim van der Harst, Cornelia M. van Duijn, Niek Verweij, James F. Wilson, Dan E. Arking, Julia Ramirez, Pier D. Lambiase, Nona Sotoodehnia, Borbala Mifsud, Christopher Newton-Cheh, Patricia B. Munroe
Publikováno v:
Nature communications, 13(1):5144. Nature Publishing Group
Nature Communications, 13(1):5144. Nature Publishing Group
Young, W J, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, J A, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, M P, van den Berg, M E, Weiss, S, Baldassari, A R, Bartz, T M, Cook, J P, Evans, D S, Freudling, R, Hines, O, Isaksen, J L, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, K A, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, H R, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, J C, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, M J, Darbar, D, De Grandi, A, De Luca, A, Ding, J, Ellervik, C, Ellinor, P T, Felix, S B, Froguel, P, Fuchsberger, C, Gögele, M, Graff, C, Graff, M, Guo, X, Hansen, T, Heckbert, S R, Huang, P L, Huikuri, H V, Hutri-Kähönen, N, Ikram, M A, Jackson, R D, Junttila, J, Kavousi, M, Kors, J A, Leal, T P, Lemaitre, R N, Lin, H J, Lind, L, Linneberg, A, Liu, S, MacFarlane, P W, Mangino, M, Meitinger, T, Mezzavilla, M, Mishra, P P, Mitchell, R N, Mononen, N, Montasser, M E, Morrison, A C, Nauck, M, Nauffal, V, Navarro, P, Nikus, K, Pare, G, Patton, K K, Pelliccione, G, Pittman, A, Porteous, D J, Pramstaller, P P, Preuss, M H, Raitakari, O T, Reiner, A P, Ribeiro, A L P, Rice, K M, Risch, L, Schlessinger, D, Schotten, U, Schurmann, C, Shen, X, Shoemaker, M B, Sinagra, G, Sinner, M F, Soliman, E Z, Stoll, M, Strauch, K, Tarasov, K, Taylor, K D, Tinker, A, Trompet, S, Uitterlinden, A, Völker, U, Völzke, H, Waldenberger, M, Weng, L-C, Whitsel, E A, Wilson, J G, Avery, C L, Conen, D, Correa, A, Cucca, F, Dörr, M, Gharib, S A, Girotto, G, Grarup, N, Hayward, C, Jamshidi, Y, Järvelin, M-R, Jukema, J W, Kääb, S, Kähönen, M, Kanters, J K, Kooperberg, C, Lehtimäki, T, Lima-Costa, M F, Liu, Y, Loos, R J F, Lubitz, S A, Mook-Kanamori, D O, Morris, A P, O'Connell, J R, Olesen, M S, Orini, M, Padmanabhan, S, Pattaro, C, Peters, A, Psaty, B M, Rotter, J I, Stricker, B, van der Harst, P, van Duijn, C M, Verweij, N, Wilson, J F, Arking, D E, Ramirez, J, Lambiase, P D, Sotoodehnia, N, Mifsud, B, Newton-Cheh, C & Munroe, P B 2022, ' Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways ', Nature Communications, vol. 13, no. 1, 5144, pp. 5144 . https://doi.org/10.1038/s41467-022-32821-z
Young, W J, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, J A, Salman, R, Noordam, R, Benjamins, J, Haessler, J, Lyytikäinen, L, Repetto, L, Concas, M P, Van Den Berg, M E, Weiss, S, Baldassari, A R, Bartz, T M, Cook, J P, Evans, D S, Freudling, R, Hines, O, Isaksen, J L, Lin, H, Mei, H, Moscati, A, Müller-nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, K A, Tarazona-santos, E, Thériault, S, Van Duijvenboden, S, Warren, H R, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, J C, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, M J, Darbar, D, De Grandi, A, De Luca, A, Ding, J, Ellervik, C, Ellinor, P T, Felix, S B, Froguel, P, Fuchsberger, C, Gögele, M, Graff, C, Graff, M, Guo, X, Hansen, T, Heckbert, S R, Huang, P L, Huikuri, H V, Hutri-kähönen, N, Ikram, M A, Jackson, R D, Junttila, J, Kavousi, M, Kors, J A, Leal, T P, Lemaitre, R N, Lin, H J, Lind, L, Linneberg, A, Liu, S, Macfarlane, P W, Mangino, M, Meitinger, T, Mezzavilla, M, Mishra, P P, Mitchell, R N, Mononen, N, Montasser, M E, Morrison, A C, Nauck, M, Nauffal, V, Navarro, P, Nikus, K, Pare, G, Patton, K K, Pelliccione, G, Pittman, A, Porteous, D J, Pramstaller, P P, Preuss, M H, Raitakari, O T, Reiner, A P, Ribeiro, A L P, Rice, K M, Risch, L, Schlessinger, D, Schotten, U, Schurmann, C, Shen, X, Shoemaker, M B, Sinagra, G, Sinner, M F, Soliman, E Z, Stoll, M, Strauch, K, Tarasov, K, Taylor, K D, Tinker, A, Trompet, S, Uitterlinden, A, Völker, U, Völzke, H, Waldenberger, M, Weng, L, Whitsel, E A, Wilson, J G, Avery, C L, Conen, D, Correa, A, Cucca, F, Dörr, M, Gharib, S A, Girotto, G, Grarup, N, Hayward, C, Jamshidi, Y, Järvelin, M, Jukema, J W, Kääb, S, Kähönen, M, Kanters, J K, Kooperberg, C, Lehtimäki, T, Lima-costa, M F, Liu, Y, Loos, R J F, Lubitz, S A, Mook-kanamori, D O, Morris, A P, O’connell, J R, Olesen, M S, Orini, M, Padmanabhan, S, Pattaro, C, Peters, A, Psaty, B M, Rotter, J I, Stricker, B, Van Der Harst, P, Van Duijn, C M, Verweij, N, Wilson, J G, Arking, D E, Ramirez, J, Lambiase, P D, Sotoodehnia, N, Mifsud, B, Newton-cheh, C & Munroe, P B 2022, ' Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways ', Nature Communications, vol. 13, no. 1, 5144 . https://doi.org/10.1038/s41467-022-32821-z
Young, W J, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, J A, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, M P, van den Berg, M E, Weiss, S, Baldassari, A R, Bartz, T M, Cook, J P, Evans, D S, Freudling, R, Hines, O, Isaksen, J L, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, K A, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, H R, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Andreasen, L, Ellervik, C, Hansen, T, Jackson, R D, Lind, L, Linneberg, A, Grarup, N, Kanters, J K, Loos, R J F, Olesen, M S & CHARGE Consortium 2022, ' Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways ', Nature Communications, vol. 13, no. 1, 5144 . https://doi.org/10.1038/s41467-022-32821-z
Young, William J; Lahrouchi, Najim; Isaacs, Aaron; Duong, ThuyVy; Foco, Luisa; Ahmed, Farah; Brody, Jennifer A; Salman, Reem; Noordam, Raymond; Benjamins, Jan-Walter; Haessler, Jeffrey; Lyytikäinen, Leo-Pekka; Repetto, Linda; Concas, Maria Pina; van den Berg, Marten E; Weiss, Stefan; Baldassari, Antoine R; Bartz, Traci M; Cook, James P; Evans, Daniel S; ... (2022). Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature communications, 13(1), p. 5144. Nature Publishing Group 10.1038/s41467-022-32821-z
Nature Communications, 13:5144. Nature Publishing Group
Nature Communications, 13(1), 5144
Nat. Commun. 13:5144 (2022)
Nature Communications, 13(1):5144. Nature Publishing Group
Young, W J, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, J A, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, M P, van den Berg, M E, Weiss, S, Baldassari, A R, Bartz, T M, Cook, J P, Evans, D S, Freudling, R, Hines, O, Isaksen, J L, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, K A, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, H R, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, J C, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, M J, Darbar, D, De Grandi, A, De Luca, A, Ding, J, Ellervik, C, Ellinor, P T, Felix, S B, Froguel, P, Fuchsberger, C, Gögele, M, Graff, C, Graff, M, Guo, X, Hansen, T, Heckbert, S R, Huang, P L, Huikuri, H V, Hutri-Kähönen, N, Ikram, M A, Jackson, R D, Junttila, J, Kavousi, M, Kors, J A, Leal, T P, Lemaitre, R N, Lin, H J, Lind, L, Linneberg, A, Liu, S, MacFarlane, P W, Mangino, M, Meitinger, T, Mezzavilla, M, Mishra, P P, Mitchell, R N, Mononen, N, Montasser, M E, Morrison, A C, Nauck, M, Nauffal, V, Navarro, P, Nikus, K, Pare, G, Patton, K K, Pelliccione, G, Pittman, A, Porteous, D J, Pramstaller, P P, Preuss, M H, Raitakari, O T, Reiner, A P, Ribeiro, A L P, Rice, K M, Risch, L, Schlessinger, D, Schotten, U, Schurmann, C, Shen, X, Shoemaker, M B, Sinagra, G, Sinner, M F, Soliman, E Z, Stoll, M, Strauch, K, Tarasov, K, Taylor, K D, Tinker, A, Trompet, S, Uitterlinden, A, Völker, U, Völzke, H, Waldenberger, M, Weng, L-C, Whitsel, E A, Wilson, J G, Avery, C L, Conen, D, Correa, A, Cucca, F, Dörr, M, Gharib, S A, Girotto, G, Grarup, N, Hayward, C, Jamshidi, Y, Järvelin, M-R, Jukema, J W, Kääb, S, Kähönen, M, Kanters, J K, Kooperberg, C, Lehtimäki, T, Lima-Costa, M F, Liu, Y, Loos, R J F, Lubitz, S A, Mook-Kanamori, D O, Morris, A P, O'Connell, J R, Olesen, M S, Orini, M, Padmanabhan, S, Pattaro, C, Peters, A, Psaty, B M, Rotter, J I, Stricker, B, van der Harst, P, van Duijn, C M, Verweij, N, Wilson, J F, Arking, D E, Ramirez, J, Lambiase, P D, Sotoodehnia, N, Mifsud, B, Newton-Cheh, C & Munroe, P B 2022, ' Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways ', Nature Communications, vol. 13, no. 1, 5144, pp. 5144 . https://doi.org/10.1038/s41467-022-32821-z
Young, W J, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, J A, Salman, R, Noordam, R, Benjamins, J, Haessler, J, Lyytikäinen, L, Repetto, L, Concas, M P, Van Den Berg, M E, Weiss, S, Baldassari, A R, Bartz, T M, Cook, J P, Evans, D S, Freudling, R, Hines, O, Isaksen, J L, Lin, H, Mei, H, Moscati, A, Müller-nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, K A, Tarazona-santos, E, Thériault, S, Van Duijvenboden, S, Warren, H R, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Alonso, A, Andreasen, L, Bis, J C, Boerwinkle, E, Campbell, A, Catamo, E, Cocca, M, Cutler, M J, Darbar, D, De Grandi, A, De Luca, A, Ding, J, Ellervik, C, Ellinor, P T, Felix, S B, Froguel, P, Fuchsberger, C, Gögele, M, Graff, C, Graff, M, Guo, X, Hansen, T, Heckbert, S R, Huang, P L, Huikuri, H V, Hutri-kähönen, N, Ikram, M A, Jackson, R D, Junttila, J, Kavousi, M, Kors, J A, Leal, T P, Lemaitre, R N, Lin, H J, Lind, L, Linneberg, A, Liu, S, Macfarlane, P W, Mangino, M, Meitinger, T, Mezzavilla, M, Mishra, P P, Mitchell, R N, Mononen, N, Montasser, M E, Morrison, A C, Nauck, M, Nauffal, V, Navarro, P, Nikus, K, Pare, G, Patton, K K, Pelliccione, G, Pittman, A, Porteous, D J, Pramstaller, P P, Preuss, M H, Raitakari, O T, Reiner, A P, Ribeiro, A L P, Rice, K M, Risch, L, Schlessinger, D, Schotten, U, Schurmann, C, Shen, X, Shoemaker, M B, Sinagra, G, Sinner, M F, Soliman, E Z, Stoll, M, Strauch, K, Tarasov, K, Taylor, K D, Tinker, A, Trompet, S, Uitterlinden, A, Völker, U, Völzke, H, Waldenberger, M, Weng, L, Whitsel, E A, Wilson, J G, Avery, C L, Conen, D, Correa, A, Cucca, F, Dörr, M, Gharib, S A, Girotto, G, Grarup, N, Hayward, C, Jamshidi, Y, Järvelin, M, Jukema, J W, Kääb, S, Kähönen, M, Kanters, J K, Kooperberg, C, Lehtimäki, T, Lima-costa, M F, Liu, Y, Loos, R J F, Lubitz, S A, Mook-kanamori, D O, Morris, A P, O’connell, J R, Olesen, M S, Orini, M, Padmanabhan, S, Pattaro, C, Peters, A, Psaty, B M, Rotter, J I, Stricker, B, Van Der Harst, P, Van Duijn, C M, Verweij, N, Wilson, J G, Arking, D E, Ramirez, J, Lambiase, P D, Sotoodehnia, N, Mifsud, B, Newton-cheh, C & Munroe, P B 2022, ' Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways ', Nature Communications, vol. 13, no. 1, 5144 . https://doi.org/10.1038/s41467-022-32821-z
Young, W J, Lahrouchi, N, Isaacs, A, Duong, T, Foco, L, Ahmed, F, Brody, J A, Salman, R, Noordam, R, Benjamins, J-W, Haessler, J, Lyytikäinen, L-P, Repetto, L, Concas, M P, van den Berg, M E, Weiss, S, Baldassari, A R, Bartz, T M, Cook, J P, Evans, D S, Freudling, R, Hines, O, Isaksen, J L, Lin, H, Mei, H, Moscati, A, Müller-Nurasyid, M, Nursyifa, C, Qian, Y, Richmond, A, Roselli, C, Ryan, K A, Tarazona-Santos, E, Thériault, S, van Duijvenboden, S, Warren, H R, Yao, J, Raza, D, Aeschbacher, S, Ahlberg, G, Andreasen, L, Ellervik, C, Hansen, T, Jackson, R D, Lind, L, Linneberg, A, Grarup, N, Kanters, J K, Loos, R J F, Olesen, M S & CHARGE Consortium 2022, ' Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways ', Nature Communications, vol. 13, no. 1, 5144 . https://doi.org/10.1038/s41467-022-32821-z
Young, William J; Lahrouchi, Najim; Isaacs, Aaron; Duong, ThuyVy; Foco, Luisa; Ahmed, Farah; Brody, Jennifer A; Salman, Reem; Noordam, Raymond; Benjamins, Jan-Walter; Haessler, Jeffrey; Lyytikäinen, Leo-Pekka; Repetto, Linda; Concas, Maria Pina; van den Berg, Marten E; Weiss, Stefan; Baldassari, Antoine R; Bartz, Traci M; Cook, James P; Evans, Daniel S; ... (2022). Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature communications, 13(1), p. 5144. Nature Publishing Group 10.1038/s41467-022-32821-z
Nature Communications, 13:5144. Nature Publishing Group
Nature Communications, 13(1), 5144
Nat. Commun. 13:5144 (2022)
The QT interval is a heritable electrocardiographic measure associated with arrhythmia risk when prolonged. Here, the authors used a series of genetic analyses to identify genetic loci, pathways, therapeutic targets, and relationships with cardiovasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdc59e352420e740fcab0595f6aaefa
https://pure.amc.nl/en/publications/genetic-analyses-of-the-electrocardiographic-qt-interval-and-its-components-identify-additional-loci-and-pathways(f14a1d7e-5b49-4b5f-9ce7-1f4c4e7d2c17).html
https://pure.amc.nl/en/publications/genetic-analyses-of-the-electrocardiographic-qt-interval-and-its-components-identify-additional-loci-and-pathways(f14a1d7e-5b49-4b5f-9ce7-1f4c4e7d2c17).html
Autor:
Martina Müller-Nurasyid, Markus M. Nöthen, Friederike Flachsbart, Annette Peters, Kaare Christensen, Sophie Chantalat, Stefan Schreiber, David Ellinghaus, Pilar Galan, Per Hoffmann, Almut Nebel, Lene Christiansen, Amke Caliebe, Hélène Blanché, Andre Franke, Konstantin Strauch, Marianne Nygaard, Wolfgang Lieb, Janina Dose, Guillermo G. Torres, Jean-François Deleuze
Publikováno v:
Torres, G G, Nygaard, M, Caliebe, A, Blanché, H, Chantalat, S, Galan, P, Lieb, W, Christiansen, L, Deleuze, J-F, Christensen, K, Strauch, K, Müller-Nurasyid, M, Peters, A, Nöthen, M M, Hoffmann, P, Flachsbart, F, Schreiber, S, Ellinghaus, D, Franke, A, Dose, J & Nebel, A 2021, ' Exome-wide association study identifies FN3KRP and PGP as new candidate longevity genes ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 76, no. 5, pp. 786-795 . https://doi.org/10.1093/gerona/glab023
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
J. Gerontol. A Biol. Sci. Med. Sci. 76, 786–795 (2021)
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
J. Gerontol. A Biol. Sci. Med. Sci. 76, 786–795 (2021)
Despite enormous research efforts, the genetic component of longevity has remained largely elusive. The investigation of common variants, mainly located in intronic or regulatory regions, has yielded only little new information on the heritability of
Autor:
Markus Scholz, Katrin Horn, Janne Pott, Arnd Gross, Marcus E. Kleber, Graciela E. Delgado, Pashupati Prasad Mishra, Holger Kirsten, Christian Gieger, Martina Müller-Nurasyid, Anke Tönjes, Peter Kovacs, Terho Lehtimäki, Olli Raitakari, Mika Kähönen, Helena Gylling, Ronny Baber, Berend Isermann, Michael Stumvoll, Markus Loeffler, Winfried März, Thomas Meitinger, Annette Peters, Joachim Thiery, Daniel Teupser, Uta Ceglarek
Publikováno v:
Nature Communications
Nat. Commun. 13:143 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Nat. Commun. 13:143 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Phytosterol serum concentrations are under tight genetic control. The relationship between phytosterols and coronary artery disease (CAD) is controversially discussed. We perform a genome-wide meta-analysis of 32 phytosterol traits reflecting resorpt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11eb6196e78d118c03f225f6cf8153f4
http://hdl.handle.net/10138/342779
http://hdl.handle.net/10138/342779
Autor:
Tove Fall, Anubha Mahajan, Dmitry Shungin, B. Balkau, Gerjan Navis, A. Metspalu, Anneli Pouta, Andrew A. Hicks, Ilja M. Nolte, Ian Ford, Aroon D. Hingorani, Stefan R Bornstein, Anuj Goel, Rona J. Strawbridge, Niek Verweij, Sarah H. Wild, Patricia B. Munroe, T.B. Harris, Jaana Lindström, Johnson Pcd., Nita G. Forouhi, Pierre Meneton, Patricia A. Peyser, Sarin A-P., Andrea Ganna, Timothy M. Frayling, Patrik K. E. Magnusson, Joanne M. Meyer, Yongmei Liu, Jeanette M. Stafford, Christian Herder, L Zudina, Maria G. Stathopoulou, May E. Montasser, Nicholas D. Hastie, Inês Barroso, Schwarz Peh., James B. Meigs, Perttu Salo, George Davey Smith, Gonneke Willemsen, Christopher J. Groves, Erik P A Van Iperen, M. A. Province, Veikko Salomaa, Naveed Sattar, Serena Sanna, Maria Dimitriou, Joop Jukema, Ulrika Krus, Albert V. Smith, Markku Laakso, James F. Wilson, George Nicholson, Loic Yengo, Tatijana Zemunik, Per Eriksson, Harold Snieder, Peter P. Pramstaller, Claudia Langenberg, R. Rauramaa, Alan R. Shuldiner, Pau Navarro, Veronique Vitart, Ross M. Fraser, Aaron Isaacs, C. Lecoeur, Jesper R. Gådin, Jackie F. Price, Letizia Marullo, L.F. Bielak, Sirkka Keinänen-Kiukaanniemi, Amélie Bonnefond, Michael Stumvoll, Alessia Faggian, Anke Tönjes, Tomohiro Tanaka, Wieland Kiess, Harry Campbell, Josée Dupuis, David Altshuler, João Fadista, Winfried März, G K Hovingh, Thomas Illig, Toby Johnson, H Grallert, Kari Stefansson, Reedik Mägi, Palmer Cna., de Geus Ejcn., Martina Müller-Nurasyid, Karen Kapur, Philippe Froguel, Dorret I. Boomsma, Anders Franco-Cereceda, Marcus E. Kleber, Boehnke M, Olga D. Carlson, Ozren Polasek, Andrew P. Morris, Alex S. F. Doney, Najaf Amin, Sara M. Willems, Vilmundur Gudnason, Jose C. Florez, Jeffery R. O'Connell, Nancy L. Pedersen, T. Saaristo, Wolffenbuttel Bhr., M. I. J. Uusitupa, Longda Jiang, Iva Miljkovic, James S. Pankow, Caroline Hayward, Hugh Watkins, Vasiliki Lagou, Johanna Kuusisto, Jaakko Tuomilehto, Alan F. Wright, Josephine M. Egan, Perry Jrb., C M van Duijn, Valeriya Lyssenko, Leif Groop, Stefania Bandinelli, Nigel W. Rayner, Tõnu Esko, Stela McLachlan, Momoko Horikoshi, Eric Boerwinkle, Rick Jansen, Richard N. Bergman, Gudmar Thorleifsson, Lyle J. Palmer, Vilmantas Giedraitis, Peter Kovacs, Nicholas J. Wareham, Luigi Ferrucci, N J Timpson, D Rybin, Anne U. Jackson, Tiinamaija Tuomi, Gonçalo R. Abecasis, Harst Pvd., Meena Kumari, Albert Hofman, Chiara Scapoli, Evelin Mihailov, Josine L. Min, Anders Hamsten, Hottenga J-J., Loos Rjf., Lars Lind, Ulf de Faire, Jaakko Kaprio, Guo Li, Beate St Pourcain, C Gieger, Amanda J. Bennett, Anna Ulrich, Nabila Bouatia-Naji, Satu Männistö, Antigone S. Dimas, Jarvelin M-R., Günther Silbernagel, F Karpe, A. Körner, David S. Siscovick, M Blüher, Rebecca J. Webster, Erik Ingelsson, Susan Campbell, Mika Kivimäki, Laura J. Rasmussen-Torvik, Heikki A. Koistinen, Sophie Visvikis-Siest, Bernhard O. Boehm, Inga Prokopenko, Ping An, Emmanouil T. Dermitzakis, Cecilia M. Lindgren, Kardia Slr., Richa Saxena, Igor Rudan, Richard M. Watanabe, Jian'an Luan, Marika Kaakinen, Shin S-Y., George Dedoussis, Panagiotis Deloukas, Mark I. McCarthy, Barbara Thorand, B.W.J.H. Penninx, Peter Vollenweider, Paul W. Franks, Leena Kinnunen, Markus Perola, Yvonne Boettcher, Timo A. Lakka, Nicole Soranzo, Stavroula Kanoni, Bakker Sjl., Winkelmann Br
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature Communications, 12(1):24, 1-18. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 12(1):24. Nature Publishing Group UK
Lagou, V, Mägi, R, Hottenga, J J, Jansen, R, Min, J L, Willemsen, G, De Geus, E J C N, Penninx, B W, Boomsma, D I, Barroso, I, Morris, A P, Prokopenko, I & MAGIC Collaboration 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24, pp. 1-18 . https://doi.org/10.1038/s41467-020-19366-9
Min, J L, St Pourcain, M U B, Timpson, N J, Davey Smith, G, Prokopenko, I & et al. 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, 24 . https://doi.org/10.1038/s41467-020-19366-9
2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-021-21276-3
Nature communications, vol. 12, no. 1, pp. 24
Nature Communications, 12(1). NATURE RESEARCH
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature Communications, 12(1):24, 1-18. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 12(1):24. Nature Publishing Group UK
Lagou, V, Mägi, R, Hottenga, J J, Jansen, R, Min, J L, Willemsen, G, De Geus, E J C N, Penninx, B W, Boomsma, D I, Barroso, I, Morris, A P, Prokopenko, I & MAGIC Collaboration 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24, pp. 1-18 . https://doi.org/10.1038/s41467-020-19366-9
Min, J L, St Pourcain, M U B, Timpson, N J, Davey Smith, G, Prokopenko, I & et al. 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, 24 . https://doi.org/10.1038/s41467-020-19366-9
2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-021-21276-3
Nature communications, vol. 12, no. 1, pp. 24
Nature Communications, 12(1). NATURE RESEARCH
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5783e9d2579548e3deb52d1bbdf19db
https://hal.univ-lorraine.fr/hal-03105716
https://hal.univ-lorraine.fr/hal-03105716
Autor:
Rui Xia, Jordana T. Bell, Roby Joehanes, Abbas Dehghan, Sharon L.R. Kardia, Erin B. Ware, Deugi Zhi, Devin Absher, Annette Peters, Martina Müller-Nurasyid, Daniel Levy, Nona Sotoodehnia, Wei Chen, Coleen M. Damcott, Lifang Hou, Donna K. Arnett, Weihua Guan, Jincheng Shen, Steve Horvath, Rory P. Wilson, Kim Valeska Emilie Braun, Lars Lind, Wei Zhao, Myriam Fornage, Shengxu Li, Mina A. Jhun, Paula Singmann, Elena Carnero-Montoro, Michael M. Mendelson, Jennifer A. Smith, Xiaoping Zhao, Marguerite R. Irvin, Bruce M. Psaty, Andrea A. Baccarelli, Jeffrey R. O'Connell, Mohammad Arfan Ikram, Traci M. Bartz, Erik Ingelsson, Klodian Dhana, Melanie Waldenberger, Stefan Gustafsson, Yii-Der Ida Chen, Thomas Meitinger, Themistocles L. Assimes, Elias Salfati, Tao Zhang, Pfeiffer Liliane, Dianjianyi Sun, Rahul Gondalia, Eric Boerwinkle, Philip S. Tsao, Christian Gieger, Eric A. Whitsel, Chen Yao, Tim D. Spector, Alan R. Shuldiner, Åsa K. Hedman, Joyce B. J. van Meurs, May E. Montasser, Anh N. Do, Mohsen Ghanbari, André G. Uitterlinden, Megan L. Grove, Jennifer A. Brody
Publikováno v:
Nature Communications, 12(1):3987. Nature Publishing Group
Nat. Commun. 12:3987 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nat. Commun. 12:3987 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Here we examine the association between DNA methylation in circulating leukocytes and blood lipids in a multi-ethnic sample of 16,265 subjects. We identify 148, 35, and 4 novel associations among Europeans, African Americans, and Hispanics, respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefd70cbd2d08c4ab44181523119b823
https://pure.eur.nl/en/publications/92253277-344e-4e65-912b-6d2b55ab4450
https://pure.eur.nl/en/publications/92253277-344e-4e65-912b-6d2b55ab4450
Autor:
Andreas Deckert, Martina Müller-Nurasyid, Christa Meisinger, Wolfgang Rathmann, Rolf Holle, Daniela Börnigen, Heiko Becher, Annette Peters, Marianne Huebner
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 18, Iss 6215, p 6215 (2021)
International Journal of Environmental Research and Public Health
Volume 18
Issue 12
Int. J. Environ. Res. Public Health 18:6215 (2021)
International Journal of Environmental Research and Public Health
Volume 18
Issue 12
Int. J. Environ. Res. Public Health 18:6215 (2021)
Resettlers are a large migrant group of more than 2 million people in Germany who migrated mainly from the former Soviet Union to Germany after 1989. We sought to compare the distribution of the major risk factors for cardiovascular disease (CVD) and
Autor:
Martina Müller-Nurasyid, Klaus Distelmaier, Julian Müller, Robert Winker, Andreas Mangold, Irene M. Lang, Stefan P. Kastl, Adelheid Panzenböck, Thomas M. Hofbauer, Evelyne Wohlschläger-Krenn, Konstantin Strauch, Anna S. Ondracek, T Scherz, Veronika Seidl, Annette Peters, Sonja Nistler
Publikováno v:
Basic Research in Cardiology
Basic Res. Cardiol. 116:29 (2021)
Basic Res. Cardiol. 116:29 (2021)
Upon activation, neutrophils release neutrophil extracellular traps (NETs), which contribute to circulating DNA burden and thrombosis, including ST-segment elevation myocardial infarction (STEMI). Deoxyribonuclease (DNase) 1 degrades circulating DNA
Autor:
Ilkka Seppälä, John C. Chambers, Marjo-Riitta Järvelin, Thomas Meitinger, Simone Wahl, Mika Ala-Korpela, Annette Peters, Michael Roden, Martina Müller-Nurasyid, Weihua Zhang, Wolfgang Rathmann, Pamela R. Matias-Garcia, Jaspal S. Kooner, Anja Kretschmer, Holger Prokisch, Johannes Kettunen, Christian Herder, Monica del C. Gomez-Alonso, Melanie Waldenberger, Mikko Hurme, Marie Loh, Sylvain Sebert, Rory P. Wilson, Olli T. Raitakari, Liliane Pfeiffer, Ville Karhunen, Kirstin Mittelstraß, Luis R. Serrano-Garcia, Terho Lehtimäki, Sacha Horn, Christian Gieger
Publikováno v:
Clinical Epigenetics
Clin. Epigenet. 13:7 (2021)
Clin. Epigenet. 13:7 (2021)
Background The discovery of robust and trans-ethnically replicated DNA methylation markers of metabolic phenotypes, has hinted at a potential role of epigenetic mechanisms in lipid metabolism. However, DNA methylation and the lipid compositions and l
Autor:
Moritz F. Sinner, Lauren Lee Rinke, Steffen Blum, M. Benjamin Shoemaker, Victoria Jacobs, Carolina Roselli, Omeed Zardkoohi, Mina K. Chung, Joylene E. Siland, Han Sun, Diane M. Crawford, Jay A. Montgomery, Michiel Rienstra, Gerhard Hindricks, Sanghamitra Mohanty, Benjamin Neumann, Tariq Z Issa, John Barnard, Isabelle C. Van Gelder, Dan M. Roden, Hugh Calkins, Petra Büttner, Rebecca Freudling, David Conen, Peter Weeke, Sébastien Thériault, Christian M. Shaffer, Andreas Bollmann, Steven A. Lubitz, Michael Kühne, Greg Michaud, Bastiaan Geelhoed, Stefan Kääb, Andrea Natale, Michael J. Cutler, Laura Ueberham, Quinn S. Wells, Stefanie Aeschbacher, Stacey Knight, Patrick T. Ellinor, Dawood Darbar, Martina Müller-Nurasyid, Jonathan D. Smith, Saman Nazarian, Jonathan Chrispin, Zachary T. Yoneda, Meelad Al Jazairi, Daniela Husser, David R. Van Wagoner
Publikováno v:
Circulation. Arrhythmia and Electrophysiology, 13(3):e007676. LIPPINCOTT WILLIAMS & WILKINS
Circ Arrhythm Electrophysiol
Circ.-Arrhythmia Electrophysiol. 13:e007676 (2020)
Circ Arrhythm Electrophysiol
Circ.-Arrhythmia Electrophysiol. 13:e007676 (2020)
Background: Ablation is a widely used therapy for atrial fibrillation (AF); however, arrhythmia recurrence and repeat procedures are common. Studies examining surrogate markers of genetic susceptibility to AF, such as family history and individual AF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daef1109764fc7f27b38fa4cc36ee446
https://research.rug.nl/en/publications/c6fc94e4-27e2-4be0-a59b-5ff323670796
https://research.rug.nl/en/publications/c6fc94e4-27e2-4be0-a59b-5ff323670796