Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leigh Wellhauser"'
Autor:
Leigh Wellhauser, Richard P. Bazinet, Denise D. Belsham, Wenyuan He, Kathyrn E Hopperton, Jim T. C. Chen, Andy Tran
Publikováno v:
Journal of Neurochemistry. 159:574-589
A contributing factor to the development of obesity is the consumption of a diet high in saturated fatty acids, such as palmitate. These fats induce hypothalamic neuroinflammation, which dysregulates neuronal function and induces orexigenic neuropept
Autor:
Jennifer A Chalmers, Prasad S Dalvi, Neruja Loganathan, Emma K McIlwraith, Leigh Wellhauser, Anaies Nazarians-Armavil, Judith A Eversley, Haneesha Mohan, Priska Stahel, Satya Dash, Michael B Wheeler, Denise D Belsham
Publikováno v:
Endocrinology
MicroRNAs (miRNAs) expressed in the hypothalamus are capable of regulating energy balance and peripheral metabolism by inhibiting translation of target messenger RNAs (mRNAs). Hypothalamic insulin resistance is known to precede that in the periphery,
Autor:
Jennifer A. Chalmers, M B Wheeler, Leigh Wellhauser, Denise D. Belsham, Serge Luquet, Prasad S. Dalvi, D Q Tran, D-Yd Han, Julien Castel, Ying Liu, V Luo
Publikováno v:
International Journal of Obesity
International Journal of Obesity, Nature Publishing Group, 2017, 41 (1), pp.149-158. ⟨10.1038/ijo.2016.183⟩
International Journal of Obesity, Nature Publishing Group, 2017, 41 (1), pp.149-158. ⟨10.1038/ijo.2016.183⟩
International audience; BACKGROUND: Consumption of dietary fat is one of the key factors leading to obesity. High-fat diet (HFD)-induced obesity is characterized by induction of inflammation in the hypothalamus; however, the temporal regulation of pr
Publikováno v:
Molecular Endocrinology. 30:402-416
The arcuate nucleus of the hypothalamus represents a key center for the control of appetite and feeding through the regulation of 2 key neuronal populations, notably agouti-related peptide/neuropeptide Y and proopimelanocortin (POMC)/cocaine- and amp