Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ke Lan"'
Publikováno v:
Thoracic Cancer, Vol 12, Iss 22, Pp 2981-2989 (2021)
Thoracic Cancer
Thoracic Cancer
Objective Few studies have focused on factors associated with the incremental cost of video‐assisted thoracoscopic surgery (VATS) in China. We aim to systematically classify the complications after VATS major lung resection and explore their correl
Autor:
Chuanyi Ning, Zhihao Meng, Shanfang Qin, Qing Lv, Hao Liang, Di Wei, Jingzhen Lai, Ke Lan, Hong Zhang, Lihua Huang, Pan Xue
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Infectious Diseases
BMC Infectious Diseases
Background In the era of anti-retroviral therapy (ART), the plasma HIV viral load (VL) is an important primary indicator for monitoring the HIV treatment response. To optimize the clinical management of HIV/AIDS patients, we investigated VL high-risk
Autor:
Xuejing Li, Lanlan Gui, Lian Yang, Qingliang Wu, Ping-Ping Zhu, Wushuang Zeng, Changxiao Liu, Wei Jia, Xian-Wen Tan, Yiting Hu, Ke Lan
Publikováno v:
Drug Metabolism and Disposition. 49:369-378
Deoxycholic acid (DCA, 3α, 12α-dihydroxy-5β-cholan-24-oic acid) is the major circulating secondary bile acid, which is synthesized by gut flora in the lower gut and selectively oxidized by CYP3A into tertiary metabolites, including 1β,3α,12α-tr
Autor:
Ke Xu, Jiali Li, Liu Cao, Yu Chen, Deyin Guo, Ruangang Pan, Yuzhen Zhang, Ke Lan, Xianying Chen, Jiejie Liu, Yingjian Li, Zhen Zhang, Li Zhou, Ying Sun, Qianyun Liu
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Coronaviruses (CoVs) can infect a variety of hosts, including humans, livestock and companion animals, and pose a serious threat to human health and the economy. The current COVID-19 pandemic, which is caused by severe acute respiratory syndrome coro
Autor:
Zhong-Sheng Jiang, Xue-Yan Liu, Yan-Qiu Lu, Min Liu, Yaokai Chen, Ke Lan, Yu-Lin Zhang, Yao Li, Yan Sun, Tong-Tong Yang, Yan-Ming Zeng
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-8 (2020)
BMC Infectious Diseases
BMC Infectious Diseases
Background This study aims to evaluate specific risk factors influencing prognosis of HIV-infected patients with toxoplasma encephalitis (TE) in order to develop a prognostic risk scoring system for them. Methods This is a six-center retrospective st
Autor:
Jiajian Shi, Lijun Yan, Mingzhu Ding, Ke Lan, Rui Sun, Jinfeng Wu, Lei Bai, Xing Wang, Yuqi Zhang, Hua Feng
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009947 (2021)
PLoS Pathogens
PLoS Pathogens
Kaposi’s sarcoma-associated herpesvirus (KSHV) preferentially infects and causes Kaposi’s sarcoma (KS) in male patients. However, the biological mechanisms are largely unknown. This study was novel in confirming the extensive nuclear distribution
Autor:
Ke Lan, Wen-Lin Wu, Yan Ni, Yu-Jie Chen, Jia Miao, Kim L. R. Brouwer, Ling-Zhi Gao, Hong Chen, Mingming Su, Ping-Ping Zhu, Shan-Shan Yin, Changxiao Liu, Liang Xu, Wei Jia, Jian Zhang
Publikováno v:
Drug Metabolism and Disposition. 47:283-294
The gut microbiota modifies endogenous primary bile acids (BAs) to produce exogenous secondary BAs, which may be further metabolized by cytochrome P450 enzymes (P450s). Our primary aim was to examine how the host adapts to the stress of microbe-deriv
Autor:
Ke Hu, Shaolin Zeng, Yang Zhao, Mengmei Wang, Dong Zhao, Zhishui Zheng, Honglin Li, Ke Xu, Xiaochen Li, Yunting Zhang, Ke Lan, Tao Wang
Publikováno v:
Virologica Sinica
We recently reported that inhibitors against human dihydroorotate dehydrogenase (DHODH) have broad-spectrum antiviral activities including their inhibitory efficacies on SARS-CoV-2 replication in infected cells. However, there are limited data from c
Autor:
Jia Miao, Ming Ming Su, Ping Ping Zhu, Li Chen, Jin Ling Zhang, Guo Yu Wang, Jian Zhang, Yu-Jie Chen, Qiu Hong Lin, Wen Xia Wang, Chang Xiao Liu, Wei Jia, Ke Lan, Xian Wen Tan
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 48(8)
This work aims to investigate how the bile acid metabolism of newborns differs from that of adults along the axis of primary, secondary, and tertiary bile acids (BAs). The total unconjugated BA profiles were quantitatively determined by enzyme digest
Autor:
Xianwen Tan, Wei Jia, Wushuang Zeng, Wenxia Wang, Liang Xu, Mingming Su, Qiuhong Lin, Ke Lan, Changxiao Liu, Lanlan Gui
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 48(6)
It was recently disclosed that CYP3A is responsible for the tertiary stereoselective oxidations of deoxycholic acid (DCA), which becomes a continuum mechanism of the host-gut microbial cometabolism of bile acids (BAs) in humans. This work aims to inv