Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Julia F. Kuder"'
Autor:
Brian A. Bergmark, Nicholas A. Marston, Candace R. Bramson, Madelyn Curto, Vesper Ramos, Alexandra Jevne, Julia F. Kuder, Jeong-Gun Park, Sabina A. Murphy, Subodh Verma, Wojtek Wojakowski, Steven G. Terra, Marc S. Sabatine, Stephen D. Wiviott, Diane Carbonneau, Raphael Poulin-Robitaille, Jeffrey Wayne, Keung Lee, Samuel Mujica Trenche, Petros Dzongowski, Daniel Gaudet, Joanna Van, Dilawar Ajani, Harold Bays, John O’Mahony, Adam Janas, John Scott, Moustafa Ashraf Moustafa, Thomas Ransom, Sabrina Benjamin, Naresh Aggarwal, Pawel Bogdanski, Douglas Friars, Robert Schlosser, Boguslaw Okopien, Madhusudan Budhraja, Lawrence Feld, Leslie Klaff, Guy Tellier, Giuseppe Mazza, Iwona Wierzbicka, Ewa Jazwinska-Tarnawska, Fernando Boccalandro, Julio Rosenstock, Elizabeth Marquez, Kim Barbel-Johnson, Katarzyna Madziarska, Kenneth Heaton, Jean-Claude Tardif, John Rubino, Miguel Trevino, Katie Moriarty, Anil Gupta, Wojciech Wojakowski, James Fidelholtz, Dinesh Gupta, Hani Alasaad, Shane Christensen, Parag Shah, Stephanie Li, Mark Sherman, Andre Frechette, Cecilia Arango, Alan Egan, Sunny Srivastava, Archna Bajaj, Carlos Ince Jr, Aleksander Zurakowski
Publikováno v:
Circulation. 145(18)
Background: Genetic loss-of-function variants in ANGPTL3 are associated with lower levels of plasma lipids. Vupanorsen is a hepatically targeted antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Methods: Adults
Autor:
Judith Hsia, Xiao Tu, James Conway, Lan-Feng Tsai, Anton I. Rosenbaum, Julia F Kuder, Richard T George, Joseph Grimsby, Ye Guan, Boaz Hirshberg, Christian T. Ruff, Sabina A. Murphy, Sotirios K. Karathanasis, Marc S. Sabatine, Michael J. Koren, B. Timothy Hummer, Judith Falloon
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(12)
Objective: Functional HDL (high-density lipoprotein) particles that facilitate cholesterol efflux may be cardioprotective. EL (endothelial lipase) hydrolyzes phospholipids promoting catabolism of HDL and subsequent renal excretion. MEDI5884 is a sele
Autor:
Giuseppe Boriani, Minggao Shi, Elliott M. Antman, Eugene Braunwald, Julia F Kuder, Christian T. Ruff, Robert P. Giugliano, Hans Lanz
Background The effects of anticoagulants at extremes of body weight (BW) are not well described. The aim of this study was to analyze the pharmacokinetics/pharmacodynamics and clinical outcomes in patients randomized to warfarin, higher dose edoxaban
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058591ee3f771b93c0121f8baae0e732
https://hdl.handle.net/11380/1227041
https://hdl.handle.net/11380/1227041
Autor:
Andrew Hamer, Anthony C Keech, Remo H.M. Furtado, Julia F Kuder, Huei Wang, Antonio Fagundes, Thomas A Zelniker, Brian A. Bergmark, Kazuma Oyama, Sabina A. Murphy, Robert P. Giugliano, Minao Tang, Marc S. Sabatine
Publikováno v:
Journal of the American College of Cardiology. 77(3)
This study sought to evaluate the ability of the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab to reduce the risk of complex coronary atherosclerosis requiring revascularization.PCSK9 inhibitors induce plaque regression a
Autor:
Remo H.M. Furtado, Róbert Gábor Kiss, Marc P. Bonaca, Stephen D. Wiviott, Itamar Raz, Francisco Padilla, Lawrence A. Leiter, Marc S. Sabatine, Julia F Kuder, Sabina A. Murphy, Darren K. McGuire, Deepak L. Bhatt, Anna Maria Langkilde, Ofri Mosenzon, Thomas A Zelniker, Ingrid Gause-Nilsson, Andrzej Budaj, John P.H. Wilding
Publikováno v:
Circulation. 141(15)
Background: Atrial fibrillation (AF) and atrial flutter (AFL) are associated with both diabetes mellitus and its related comorbidities, including hypertension, obesity, and heart failure (HF). SGLT2 (sodium-glucose cotransporter 2) inhibitors have be
Autor:
Rangasamy Muthusamy, Marc S. Sabatine, Francesco Franchi, Marc Cohen, Marc P. Bonaca, Ramzi A. Ajjan, Julia F Kuder, Robert F. Storey, Philippe Gabriel Steg, Mark R Thomas, Heather M Judge, Dominick J. Angiolillo, Fabiana Rollini, Deepak L. Bhatt, Arif J. Ahsan
Publikováno v:
Thrombosis and Haemostasis. 117:940-947
SummaryDiabetes increases cardiovascular risk and reduces pharmacodynamic response to some oral antiplatelet drugs. This study aimed to determine whether ticagrelor 60 mg twice daily (bid) provided potent and consistent platelet inhibition in patient
Autor:
Petr Jarolim, Marc A. Pfeffer, Julia F Kuder, Brian A. Bergmark, David A. Morrow, Marc S. Sabatine, Scott D. Solomon, Eugene Braunwald, Jacob A. Udell
AIMS Klotho, an essential co-receptor for fibroblast growth factor (FGF)-23, has potentially beneficial inhibitory effects on the renin-angiotensin system. Limited data exist on the prognostic value of Klotho and FGF-23 levels in combination or their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d872158b157a55c46b22e93dc70514
https://europepmc.org/articles/PMC6458082/
https://europepmc.org/articles/PMC6458082/
Autor:
Peter W.F. Wilson, Kim A. Eagle, Shinya Goto, Sidney C. Smith, E. Magnus Ohman, KyungAh Im, Julia F Kuder, Deepak L. Bhatt, Matthew A. Cavender, Ph. Gabriel Steg
Publikováno v:
Circulation. 132:923-931
Background— Despite the known association of diabetes mellitus with cardiovascular events, there are few contemporary data on the long-term outcomes from international cohorts of patients with diabetes mellitus. We sought to describe cardiovascular
Autor:
David A. Morrow, Sabina A. Murphy, Terje R. Pedersen, Anthony C Keech, Gaetano M. De Ferrari, Danielle M Forni, Marc S. Sabatine, Robert P. Giugliano, Kurt Huber, Narimon Honarpour, Julia F Kuder, Basil S. Lewis, Peter S. Sever, Stephen D. Wiviott, Christopher E. Kurtz
Publikováno v:
JAMA Cardiol
IMPORTANCE: The PCSK9 inhibitor evolocumab reduced major vascular events in the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) trial, yet the types and sizes of myocardial outcomes in FOURIER h
Autor:
Michele Mercuri, Elliott M. Antman, Eugene Braunwald, Howard Rutman, Minggao Shi, Hans Lanz, Julia F Kuder, Christian T. Ruff, Robert P. Giugliano, Giuseppe Boriani
Publikováno v:
European heart journal. 40(19)
Aims To investigate the relationship between body mass index (BMI) and outcomes in patients with atrial fibrillation (AF). Methods and results In the ENGAGE AF-TIMI 48 trial, patients with AF were randomized to warfarin (international normalized rati