Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jason K. Sicklick"'
Co-Localization of Gastrointestinal Stromal Tumors (GIST) and Peritoneal Mesothelioma: A Case Series
Autor:
Asimina S, Courelli, Ashwyn K, Sharma, Lisa, Madlensky, Yoon Young, Choi, Sam, Li, Shirley, Sarno, Kaitlyn, Kelly, Winta, Mehtsun, Santiago, Horgan, Olivier, Harismendy, Joel M, Baumgartner, Jason K, Sicklick
Publikováno v:
Annals of Surgical Oncology. 29:7542-7548
Gastrointestinal stromal tumor (GIST) is associated with increased risk of additional cancers. In this study, synchronous GIST, and peritoneal mesothelioma (PM) were characterized to evaluate the relationship between these two cancers.A retrospective
Autor:
Pradip De, J. Jack Lee, Michael E. Hahn, Shumei Kato, Hitendra Patel, Jason K. Sicklick, Brian Leyland-Jones, Jessica Guido, Benjamin M. Solomon, Mina Nikanjam, Scott M. Lippman, Paul T. Fanta, Casey Williams, Sarah Boles, Rana R. McKay, Razelle Kurzrock, Jeffrey S. Ross, Ryosuke Okamura, Amy Krie
Publikováno v:
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Background Malignancies are molecularly complex and become more resistant with each line of therapy. We hypothesized that offering matched, individualized combination therapies to patients with treatment-naïve, advanced cancers would be feasible and
Autor:
Ethan Sokol, Philip R Cohen, Jason K. Sicklick, Razelle Kurzrock, Alexis Phillips, Huan-You Wang, David C. Fajgenbaum, Aaron M. Goodman, Ah-Reum Jeong
Publikováno v:
Eur J Haematol
Objectives Castleman disease (CD) is a heterogeneous group of disorders involving systemic inflammation and lymphoproliferation. Recently, clonal mutations have been identified in unitcentric CD (UCD) and idiopathic multicentric CD (iMCD), suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50b145115ae47fb0e9ebf302d447d0b
https://europepmc.org/articles/PMC9624446/
https://europepmc.org/articles/PMC9624446/
Autor:
Jessica L. Davis, Rowan Ustoy, Chih Min Tang, Sudeep Banerjee, Markku Miettinen, Jason K. Sicklick, Adam M. Burgoyne, Sangkyu Noh, Christopher L. Corless, Mayra Yebra
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-8 (2019)
Journal of translational medicine, vol 17, iss 1
Journal of Translational Medicine
Journal of translational medicine, vol 17, iss 1
Journal of Translational Medicine
Background Plexiform fibromyxoma (PF) is a rare gastric tumor often confused with gastrointestinal stromal tumor. These so-called “benign” tumors often present with upper GI bleeding and gastric outlet obstruction. It was recently demonstrated th
Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study
Autor:
Ryosuke Okamura, Razelle Kurzrock, J. Jack Lee, Philip J. Stephens, Michael E. Hahn, Shumei Kato, Amy Krie, Jennifer Webster, Jeffrey S. Ross, Brian Leyland-Jones, David Piccioni, Pradip De, Scott M. Lippman, Maria Schwaederle, Adam Benson, Paul T. Fanta, Vincent A. Miller, Jason K. Sicklick, Casey Williams
Publikováno v:
Nature medicine, vol 25, iss 5
Nature medicine
Nature medicine
Cancer treatments have evolved from indiscriminate cytotoxic agents to selective genome- and immune-targeted drugs that have transformed outcomes for some malignancies.1 Tumor complexity and heterogeneity suggest that the “precision medicine” par
Autor:
Ryosuke Okamura, Jason K. Sicklick, Joel M. Baumgartner, Lawrence Leichman, Shumei Kato, Hitendra Patel, Scott M. Lippman, Paul T. Fanta, Razelle Kurzrock, Kaitlyn J. Kelly
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 24, iss 24
Purpose: Esophageal, gastroesophageal junction, and gastric adenocarcinoma (herein gastroesophageal adenocarcinomas) are associated with poor prognosis and limited systemic treatment options. To further understand the genomic landscape of gastroesoph
Autor:
Jason K. Sicklick, Shumei Kato, Ryosuke Okamura, Sophia Gumas, Razelle Kurzrock, Suzanna Lee, Caroline M. Weipert, Jennifer Saam
Publikováno v:
JCO Precision Oncology
PURPOSE Cancer of unknown primary (CUP) is a metastatic disease with unidentifiable primary tumor. Somatic alterations can be assessed noninvasively via liquid biopsies interrogating cell-free DNA (cfDNA). METHODS We evaluated 1,931 patients with CUP
Autor:
Noor Khalid, Razelle Kurzrock, Jacob J. Adashek, Suzanna Lee, Shumei Kato, Jason K. Sicklick, Van Thomas Nguyen, Ryosuke Okamura
Publikováno v:
JCI insight, vol 6, iss 1
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
BACKGROUND Although CDK4/6 inhibitors are an established treatment for hormone receptor–positive, HER2-negative metastatic breast cancers, their benefit in other malignancies remains limited.METHODS We investigated factors associated with clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66de530f4ac6efbc82971e89d868547b
https://escholarship.org/uc/item/66p2z8d2
https://escholarship.org/uc/item/66p2z8d2
Autor:
Sudeep, Banerjee, Hyunho, Yoon, Stephanie, Ting, Chih-Min, Tang, Mayra, Yebra, Alexander T, Wenzel, Huwate, Yeerna, Jill P, Mesirov, Robert J, Wechsler-Reya, Pablo, Tamayo, Jason K, Sicklick
Publikováno v:
Mol Cancer Ther
Gastrointestinal stromal tumor (GIST) is commonly driven by oncogenic KIT mutations that are effectively targeted by imatinib, a tyrosine kinase inhibitor (TKI). However, IM does not cure GIST and adjuvant therapy only delays recurrence in high-risk
Autor:
Sandy S Bohan, Razelle Kurzrock, Vincent A. Miller, Shumei Kato, Jason K. Sicklick, Ryosuke Okamura, Scott M. Lippman, Brian Leyland-Jones
Publikováno v:
The oncologist, vol 25, iss 11
The Oncologist
The Oncologist
Background Precision oncology uses molecular profiling of tumors to identify biomarker‐tailored therapies for patients in the hope of improving outcomes. Typically, only a minority of patients receives evaluable matched treatment. This study explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7668488922f2d1bd0f8d83a5ae107f7b
https://escholarship.org/uc/item/9vw2n2j9
https://escholarship.org/uc/item/9vw2n2j9