Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Helen E. Ritchie"'
Autor:
Matthew S. Edwards, David S. Winlaw, Dimuthu Alankarage, Kavitha R Iyer, Bernadette C Hanna, Steven Monger, Gavin Chapman, Victoria C. O'Reilly, Justin O. Szot, Michelle Yam, Annabelle Enriquez, Julie L. M. Moreau, Ella M M A Martin, Sally L. Dunwoodie, Duncan B. Sparrow, Helen E. Ritchie, Joelene A Greasby, Eleni Giannoulatou, Hongjun Shi, Gillian M. Blue, Eddie I P, Stuart M. Grieve
Publikováno v:
Hum Mol Genet
Congenital heart disease (CHD) is the most common birth defect and brings with it significant mortality and morbidity. The application of exome and genome sequencing has greatly improved the rate of genetic diagnosis for CHD but the cause in the majo
Publikováno v:
Australian and New Zealand Journal of Obstetrics and Gynaecology. 57:162-167
Background MotherSafe is a free telephone-based counselling service for the general public and healthcare providers concerned about exposures during pregnancy and breastfeeding. Calls relating to paternal exposures are less common, but can cause dist
Publikováno v:
Physiological Reports
A slow embryonic heart rate in early‐mid gestation is associated with increased risk of embryonic death and malformation, however, the long‐term consequences remain unknown. We administered Dofetilide (Dof, 2.5 mg/kg), a drug that produces embryo
Publikováno v:
Anatomical sciences education. 12(3)
This study evaluates a cooperative learning approach for teaching anatomy to health science students incorporating small group and peer instruction based on the jigsaw method first described in the 1970's. Fifty-three volunteers participated in abdom
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0195101 (2018)
PLoS ONE
PLoS ONE
Background Safe use of medications during pregnancy requires a comprehensive understanding of risk-benefit profiles for individual treatments. Pharmacists are supported in this aspect by clinical information agencies (e.g. MotherSafe, a telephone-bas
Publikováno v:
Reproductive Toxicology. 26:267-272
Solvent abuse during pregnancy results in a clinical pattern of adverse outcomes including deafness. The aim of this project was to determine whether high doses of toluene for a short duration during pregnancy produced adverse outcomes in the fetal r
Publikováno v:
Journal of Ethnopharmacology. 118:127-132
Aim of study Hawthorn (Crataegus) has a long history as a medicine. The current clinical use of hawthorn as a heart medicine dates back to the late 19th century. It is well tolerated clinically yet contraindicated in pregnancy. Materials and methods
Publikováno v:
Toxicological Sciences. 68:200-206
Male Vietnam veterans have repeatedly expressed concern that exposure to herbicides in Vietnam may have caused birth defects in their offspring. The second most used herbicide was a mixture of 2,4-D and picloram called Agent White. This study is an i
Publikováno v:
Reproductive Toxicology. 16:281-289
The second most used herbicide in the Vietnam war was Agent White, which contained the active components 2,4-dichlorophenoxyacetic acid (2,4-D) and 4-amino-3,5,6-trichloropicolinic acid (picloram). The herbicide formulation Tordon 75D® is similar in
Autor:
Caroline Gavin, Muhammad Khalid Khan, Mats Nilsson, William S. Webster, Deena Ababneh, Kristin Carlsson, Dominique Abela, Helen E. Ritchie
Publikováno v:
Birth defects research. Part B, Developmental and reproductive toxicology. 89(5)
This study investigated the effects of a range of pharmaceutical drugs with ion channel-blocking activity on the heart of gestation day 13 rat embryos in vitro. The general hypothesis was that the blockade of the I(Kr)/hERG channel, that is highly im