Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emanuela Felley-Bosco"'
Autor:
Kathrin, Oehl, Bart, Vrugt, Ulrich, Wagner, Michaela B, Kirschner, Mayura, Meerang, Walter, Weder, Emanuela, Felley-Bosco, Bernd, Wollscheid, Katrin, Bankov, Melanie C, Demes, Isabelle, Opitz, Peter J, Wild
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(8)
The clinical standard treatment for patients with malignant pleural mesothelioma (MPM) includes a cisplatin-based chemotherapy, leading to reduction of tumor size in only a minority of patients. Predicting response to chemotherapy in patients with MP
Autor:
Sara L. Sinicropi-Yao, Katie Lomeo, Meena Choi, Joseph M. Amann, David P. Carbone, Rolf A. Stahel, Ferdinando Cerciello, Olga Vitek, Emanuela Felley-Bosco, Bruce W. S. Robinson, Jenette Creaney, Harvey I. Pass
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background:We have verified a mass spectrometry (MS)–based targeted proteomics signature for the detection of malignant pleural mesothelioma (MPM) from the blood.Methods:A seven-peptide biomarker MPM signature by targeted proteomics in serum was id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e75c82b78d7f4ab8472641d0b5b1e14
Publikováno v:
Chemical research in toxicology. 31(10)
Asbestos fibers are naturally occurring silicates that have been extensively used in the past, including house construction, but because of their toxicity, their use has been banned in 63 countries. Despite this, more than one million metric tons of
Autor:
Walter Weder, Serre-Beinier, Frédéric Triponez, C Otterstrom, Isabelle Opitz, Alex Soltermann, Emanuela Felley-Bosco, Rolf A. Stahel, John Robert
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Vol. 110, No 8 (2014) pp. 2040-6
British Journal of Cancer, Vol. 110, No 8 (2014) pp. 2040-6
Background: The pro-inflammatory cytokine migration inhibitory factor (MIF) and its receptor CD74 have been proposed as possible therapeutic targets in several cancers. We studied the expression of MIF and CD74 together with calretinin in specimens o
Autor:
Walter Weder, Rolf A. Stahel, Alex Soltermann, Svenja Thies, Mayura Meerang, Byron K.Y. Bitanihirwe, Holger Moch, Ghassan Allo, Emanuela Felley-Bosco, Marc de Perrot, Martina Friess, Isabelle Opitz, Lukas Frischknecht, Ming-Sound Tsao, Burkhardt Seifert
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study o
Introduction: The prognostic significance of activity biomarkers within the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling pathway was assessed in two independent cohorts of malignant pleural mesothelioma (MPM) pa
Autor:
Kristiaan Nackaerts, Andreas Rusch, Rolf A. Stahel, Walter Weder, Emanuela Felley-Bosco, Gabriela Ziltener
Publikováno v:
Lung cancer (Amsterdam Netherlands)
Objective 23% of mesothelioma tumor specimens have a mutation in the BRCA1-associated protein 1 (BAP1) gene and germline BAP1 mutations predispose to malignant pleural mesothelioma (MPM). Our aim was to investigate germline BAP1 mutations in sporadic
Autor:
Isabelle Opitz, Walter Weder, Ubiratan Moura, Svenja Thies, Yandong Shi, Hubert Rehrauer, Rolf A. Stahel, Emanuela Felley-Bosco, Alex Soltermann
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose: The aim of this study was to assess the activity of hedgehog signaling pathway in malignant pleural mesothelioma (MPM). Experimental Design: The expression of hedgehog signaling components was assessed by quantitative PCR and in situ hybridi
Autor:
Ferdinando Cerciello, Annemarie Ziegler, Rolf A. Stahel, Colette Bigosch, Emanuela Felley-Bosco, Reto Ossola, Bernd Wollscheid, Alex Soltermann, Damaris Bausch-Fluck
Publikováno v:
Lung Cancer. 75:189-196
Identification of new markers for malignant pleural mesothelioma (MPM) is a challenging clinical need. Here, we propose a quantitative proteomics primary screen of the cell surface exposed MPM N-glycoproteins, which provides the basis for the develop
Autor:
Larry K. Keefer, Andrea M. A. Pfeifer, Stefan Ambs, Katherine Macé, Emanuela Felley-Bosco, Jovan Mirkovitch, Curtis C. Harris
Publikováno v:
Carcinogenesis. 16:2069-2074
Nitric oxide (NO) is a cellular messenger which is mutagenic in bacteria and human TK6 cells and induces deamination of 5-methylcytosine (5meC) residues in vitro. The aims of this study were : (i) to investigate whether NO induces 5meC deamination in
Autor:
Isabelle Opitz, Emanuela Felley-Bosco, Hubert Rehrauer, Alex Soltermann, Giulia Pasello, Rolf A. Stahel, Roy Sidi, Walter Weder, Michaela Tutic
The aim of this study was to assess the induction of senescence markers versus apoptosis pathways in malignant pleural mesothelioma (MPM) tumour samples before and after neo-adjuvant platinum-based chemotherapy and to investigate their relationship w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba1124f1ed25aaa67032208c6c45e82