Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Edward Hammond"'
Autor:
Edward Hammond, Darryn Bampton, Keith Dredge, Liwen Lin, Carleen Cullinane, Paul Handley, Todd V. Brennan, Tomislav Karoli, Yiping Yang, Nicole M. Haynes, Fleur Lanksheer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Pixatimod (PG545) is a novel clinical-stage immunomodulatory agent capable of inhibiting the infiltration of tumor-associated macrophages (TAMs) yet also stimulate dendritic cells (DCs), leading to activation of natural killer (NK) cells.
Autor:
Gan-Lin Zhang, Cynthia A. Loomis, Haining Yang, Uri Barash, Chandra Goparaju, Edward Hammond, Neta Ilan, Arnon Nagler, Moshe Lapidot, Israel Vlodavsky, Sari Feld, Harvey I. Pass, Andre L. Moreira, Yaniv Zohar, Jin-Ping Li
BACKGROUND: Mammalian cells express a single functional heparanase, an endoglycosidase that cleaves heparan sulfate and thereby promotes tumor metastasis, angiogenesis, and inflammation. Malignant mesothelioma is highly aggressive and has a poor prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b975a61bd90b7ad6147c7432bddefda1
https://europepmc.org/articles/PMC6186523/
https://europepmc.org/articles/PMC6186523/
Autor:
Jason D. Lickliter, Glynn Morrish, Keith Dredge, Liwen Lin, Edward Hammond, Michael P. Brown, Fleur Lankesheer, Todd V. Brennan, Yiping Yang, Michael Millward, Darryn Bampton, Paul Handley
Publikováno v:
British Journal of Cancer
Background: PG545 (pixatimod) is a novel immunomodulatory agent, which has been demonstrated to stimulate innate immune responses against tumours in preclinical ca ncer models. Methods: This Phase I study investigated the safety, tolerability, pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc89d836cf533c7946d9d73812d95b2
https://hdl.handle.net/11541.2/131335
https://hdl.handle.net/11541.2/131335
Autor:
Iyad Khamaysi, Ahmad Hassan, Omri Nativ, Edward Hammond, Zaid Abassi, Gloria Bellin, Antonio Lupo, Maurizio Onisto, Preeti Singh, Samuel N. Heyman, Rabia Shekh Muhammad, Neta Ilan, Giovani Gambaro, Israel Vlodavsky, Valentina Masola, Shadi Hamoud, Gianluigi Zaza
Publikováno v:
Oncotarget
// Zaid Abassi 1,2 , Shadi Hamoud 3 , Ahmad Hassan 4 , Iyad Khamaysi 5 , Omri Nativ 1 , Samuel N. Heyman 6 , Rabia Shekh Muhammad 3 , Neta Ilan 7 , Preeti Singh 7 , Edward Hammond 8 , Gianluigi Zaza 9 , Antonio Lupo 9 , Maurizio Onisto 10 , Gloria Be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f22525d0306c89d13f512fb406f04a9
http://hdl.handle.net/11562/962711
http://hdl.handle.net/11562/962711
Autor:
Tomislav Karoli, Ligong Liu, Jon K. Fairweather, R. S. Addison, Cai Ping Li, Edward Hammond, Kicki Bergefall, Edward Trybala, Vito Ferro, Siska Cochran
Publikováno v:
Journal of Medicinal Chemistry. 48:8229-8236
The phosphosulfomannan 1 (PI-88) is a mixture of highly sulfated oligosaccharides that is currently undergoing clinical evaluation in cancer patients. As well as its anticancer properties, 1 displays a number of other interesting biological activitie
Autor:
Ken D. Johnstone, Francis C. K. Chiu, Ligong Liu, David M. Shackleford, Tomislav Karoli, Keith Dredge, Elizabeth Copeman, Susan A. Charman, Cai Ping Li, William N. Charman, Job Harenberg, Ian Bytheway, Vito Ferro, Kat Davis, Thomas J. Gonda, Edward Hammond, Edmund Kostewicz
Publikováno v:
Journal of medicinal chemistry. 53(4)
A series of polysulfated penta- and tetrasaccharide glycosides containing α(13)/α(12)-linked mannose residues were synthesized as heparan sulfate (HS) mimetics and evaluated for their ability to inhibit angiogenesis. The compounds bound tightly to
Publikováno v:
Journal of clinical epidemiology. 50(12)
The Duke Case-Mix System (DUMIX), which combines age, gender, patient-reported perceived and physical health status, and provider-reported or auditor-reported severity of illness to classify patients by their risk of high future utilization, explaine