Zobrazeno 71 - 80
of 187
pro vyhledávání: '"Colin P.N. Dinney"'
Autor:
Mark F. Munsell, H. Barton Grossman, Piyush K. Agarwal, Colin P.N. Dinney, Wassim Kassouf, Louis L. Pisters, Arlene O. Siefker-Radtke, David A. Swanson, Ashish M. Kamat, Dan Leibovici
Publikováno v:
Urology. 73:147-152
Objectives Persistent nodal disease in the surgical specimen (pN+) after preoperative chemotherapy for urothelial carcinoma is associated with a poor prognosis. To improve our understanding regarding the outcomes of such patients, we performed a retr
Autor:
Wassim Kassouf, Teruo Inamoto, Peter C. Black, Mark B. Fisher, David Gallagher, David J. McConkey, Colin P.N. Dinney, Gordon A. Brown, Liana Adam, Tony Luongo, Menashe Bar-Eli
Publikováno v:
Journal of Urology. 180:1146-1153
The epidermal growth factor receptor inhibitor gefitinib (Iressa) is currently being studied in patients with bladder cancer and it has significant anti-angiogenic activity. We investigated the relationship between the modulation of vascular endothel
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 17:2445-2450
Purpose: Loss of chromosome 9p21 is one of the most frequent genomic alterations in bladder cancer. Alterations of 9p21 and p16 are also frequently seen in the epithelial cells of chronic smokers. We hypothesize that 9p21 is a molecular target of ben
Publikováno v:
Cancer Research. 68:2530-2537
MicroRNAs (miRNA) are small noncoding RNA molecules involved in a diversity of cellular functions. Although it has been reported that global suppression of the miRNA biogenesis pathway leads to enhanced tumorigenesis, the effect of common genetic var
Autor:
Mark F. Munsell, Ameeta Arora, Marissa Shrader, David J. McConkey, Liana Adam, Teruo Inamoto, Colin P.N. Dinney, Xifeng Wu, Arlene O. Siefker-Radtke, Gordon A. Brown, Dan Theodorescu, Peter C. Black, Menashe Bar-Eli
Publikováno v:
Clinical Cancer Research. 14:1478-1486
Purpose: Epidermal growth factor receptor (EGFR) is an attractive target for the treatment of urothelial carcinoma, but a clinical response can be expected in only a small proportion of patients. The aim of this study was to define molecular markers
Autor:
Jolanta Bondaruk, Tomasz Tuziak, David J. McConkey, Menashe Bar-Eli, Bogdan Czerniak, Liana Adam, Colin P.N. Dinney, Wassim Kassouf, Sangkyou Lee, Keith A. Baggerly, Gordon A. Brown, Caimiao Wei, Peter C. Black
Publikováno v:
Journal of Urology. 179:353-358
Expression of various members of the ErbB family (epidermal growth factor receptor/ErbB-1, ErbB-2, ErbB-3 and ErbB-4) is associated with disease stage and survival in patients with urothelial carcinoma. We examined the correlation of ErbB family rece
Autor:
Scott M. Lippman, Anita L. Sabichi, Mary Wargo, Seth P. Lerner, Howard L. Parnes, H. Barton Grossman, Archie Bleyer, Dean E. Brenner, David F. Penson, John L. Clifford, Nancy P. Caraway, Ashish M. Kamat, Louis L. Pisters, Ruth L. Katz, Surena F. Matin, Daniel W. Lin, E. Neely Atkinson, William H. Sanders, George P. Hemstreet, Colin P.N. Dinney
Publikováno v:
Clinical Cancer Research. 14:224-229
Purpose: The study aims to evaluate the efficacy and toxicity of fenretinide in preventing tumor recurrence in patients with transitional cell carcinoma (TCC) of the bladder. Experimental Design: We conducted a multicenter phase III, randomized, plac
Autor:
H. Barton Grossman, Colin P.N. Dinney, Curtis A. Pettaway, Ashish M. Kamat, Mark F. Munsell, J. Erik Busby, Gordon A. Brown, Surena F. Matin
Publikováno v:
Urology. 70:252-256
OBJECTIVES To evaluate whether the clinical grade predicts the final pathologic stage in upper urinary tract transitional cell carcinoma. METHODS We retrospectively reviewed the records of 184 consecutive patients undergoing nephroureterectomy for up
Publikováno v:
Expert Review of Anticancer Therapy. 7:1015-1026
Pure urothelial carcinoma makes up 90-95% of all bladder cancer. The remaining 5-10% represent urothelial carcinoma with aberrant differentiation patterns and nonurothelial carcinoma. Reviews on this topic often focus on the pathological features of
Autor:
Lina Shao, Xin Lin, Hushan Yang, Xifeng Wu, Maosheng Huang, Christopher G. Wood, Colin P.N. Dinney
Publikováno v:
Cancer. 110:282-288
BACKGROUND DNA damage induced by mutagens has been associated with an individual's susceptibility to cancer. METHODS In the current study, which involved 193 renal cell carcinoma (RCC) patients and 193 controls, DNA damage before mutagen induction (b